DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arr1 and arrb2a

DIOPT Version :9

Sequence 1:	NP_001246073.1	Gene:	Arr1 / 35078	FlyBaseID:	FBgn0000120	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_009303544.1	Gene:	arrb2a / 321378	ZFINID:	ZDB-GENE-030131-29	Length:	414	Species:	Danio rerio

Alignment Length:	358	Identity:	158/358 - (44%)
Similarity:	236/358 - (65%)	Gaps:	13/358 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KVFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDDEM 70
            :||||.|||..:|:|:.:|||||.:..|:|:||:|::|.||:: :||:||.|.|.|||||||.::
Zfish     8 RVFKKSSPNCKVTVYLGKRDFVDHLDHVDPVDGVILVDPEYLK-DRKVFVTLTCAFRYGREDLDV 71

  Fly    71 IGLRFQKELTLVSQQVCPPQKQDIQ-LTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKASD 134
            :||.|:|:|.:.:.|..||..::.: .:::|||||||||.|||||...:|.:.|.||.||....|
Zfish    72 LGLSFRKDLYIFTFQAYPPIPEESKPHSRLQERLLKKLGQNAYPFHFSIPQNLPCSVTLQPGPED 136

  Fly   135 ESQPCGVQYFVKIFTGDSDCDRSHRRSTINLGIRKVQYAPTKQGIQPCTVVRKDFLLSPGELELE 199
            ..:.|||.:.::.|...|..:::|:|:::.|.||||||||.|.|.||.....:.||:|...|.||
Zfish   137 TGKACGVDFEIRAFCAKSMEEKNHKRNSVRLVIRKVQYAPEKPGPQPMVETTRSFLMSDRSLHLE 201

  Fly   200 VTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCPLN 264
            .:|||:||:|||.||||:.|.|||.|.||::|..|:|..|:.||...|::..:|.:|..:  .:.
Zfish   202 ASLDKELYYHGEPISVNVHVTNNSTKTVKRVKISVRQYADICLFSTAQYKCPVAQIEADD--QVA 264

  Fly   265 PGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIASQDARDAFGIIVSYAVKVKLF 329
            ..|:..||..|.|||..|.::.|:|::|.:|.:||.|||:|::.....::..|::|||.|||||.
Zfish   265 SSSTFCKVYTLTPTLNNNREKRGLALDGKLKHEDTNLASSTIVKDVSNKEVLGVLVSYRVKVKLV 329

  Fly   330 LGALGG--------ELCAELPFILMHPKPSRKA 354
            : :.||        ::..||||:|||||||..:
Zfish   330 V-SRGGLLSSLLERDVSVELPFVLMHPKPSESS 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arr1	NP_001246073.1	Arrestin_N	17..173	CDD:304627	70/156 (45%)
Arr1	NP_001246073.1	Arrestin_C	192..350	CDD:214976	69/165 (42%)
arrb2a	XP_009303544.1	Arrestin_N	19..175	CDD:278754	70/156 (45%)
arrb2a	XP_009303544.1	Arrestin_C	194..357	CDD:214976	69/165 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52566
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030