DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arr1 and CG32683

DIOPT Version :9

Sequence 1:	NP_001246073.1	Gene:	Arr1 / 35078	FlyBaseID:	FBgn0000120	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001285084.1	Gene:	CG32683 / 31970	FlyBaseID:	FBgn0052683	Length:	804	Species:	Drosophila melanogaster

Alignment Length:	533	Identity:	127/533 - (23%)
Similarity:	197/533 - (36%)	Gaps:	196/533 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KVFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDDEM 70
            :|:||.|||.::|||:..|:...:......:.||:.:|.:.: |..:::.||...|||||||:|:
  Fly   103 RVYKKTSPNCVLTLYLPTREITLTGNNPSVLRGIVYVDPKAI-QGYRVYAQLTLTFRYGREDEEV 166

  Fly    71 IGLRFQKELTLVSQQVCPPQKQDI--QLTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKAS 133
            :||||..|..:...|:.|..::..  .|:.:||.|:|:||..|:||.:.:...:|.||.|.....
  Fly   167 MGLRFCNEAIMSLHQIWPRLEEPTPESLSPLQEALMKRLGDGAHPFTLSLSSYAPPSVQLVPAKR 231

  Fly   134 DESQPCGVQYFVKIFTGDSDCDRSHRRSTINLGIRKV-------------QYAP----------- 174
            ....|.|..|.|:.|..|...::.|||:::.:|:|.:             |||.
  Fly   232 YYGAPIGTSYDVRCFIADKTDEKFHRRASVKMGVRVIYRTDVFHQHLAPEQYAAFAGRQNIAQSP 296

  Fly   175 --------------------------------------------------------------TKQ 177
                                                                          :|.
  Fly   297 PASATPPSCGEGGEQHTTHTQQQSQSQPSSGSKHKSKSERGDSFPKLRLSPKSFRFSGRFGRSKS 361

  Fly   178 GIQPCT--------------------------------------------VVRKDFLLSPGELEL 198
            .|:.|.                                            .|.|.|||..|.:.|
  Fly   362 EIEKCPNDPFHSYSKSFQEHCDSMLPPHTGAGVTGGIGGVSVGPCGGPQGSVDKPFLLHDGRVGL 426

  Fly   199 EVTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCP- 262
            ..:|||..|.|||.:.|.:.:||:|.|.|:|::....|.|||.:|.||:|:|.:|  ::....|
  Fly   427 RASLDKGWYTHGEDVQVTVNIRNDSRKTVRKVRVCAIQHVDVCMFNNGKFKNVVA--DSDNVTPP 489

  Fly   263 ----LNPGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIAS-------------- 309
                :..|:||...:.|.|.  ....:..||:|..::|.......|..||:
  Fly   490 VDRTVAAGASLNTTVTLRPQ--RGPTKNWIALEDTLQRSTEPEEITGAIAASAIRSPHFVMQNAQ 552

  Fly   310 ----------------------------------------QDARDAFGIIVSYAVKVKLFLGALG 334
                                                    .:.|:.|.|.|||.|||||.|..:|
  Fly   553 LLGGCGHPLGSPALVTPHPHLWQPGSQGQGQPGNPNSGGGNEERNVFAIYVSYYVKVKLTLSGMG 617

  Fly   335 GELCAELPFILMH 347
            |||..:|||:|:|
  Fly   618 GELSLKLPFVLVH 630

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arr1	NP_001246073.1	Arrestin_N	17..173	CDD:304627	51/170 (30%)
Arr1	NP_001246073.1	Arrestin_C	192..350	CDD:214976	60/215 (28%)
CG32683	NP_001285084.1	Arrestin_N	135..268	CDD:304627	46/133 (35%)
CG32683	NP_001285084.1	Arrestin_C	421..632	CDD:214976	60/214 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470068
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3865
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.802101	Normalized mean entropy	S2648
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D34511at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800