Protein Alignment Arr1 and Arrb2

DIOPT Version :10

• Sequence 1: NP_476681.1
• Gene: Arr1 / 35078
• FlyBaseID: FBgn0000120
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_001258287.1
• Gene: Arrb2 / 216869
• MGIID: 99474
• Length: 421
• Species: Mus musculus
• Alignment Length: 347
• Identity: 151/347 - (43%)
• Similarity: 233/347 - (67%)
• Gaps: 6/347 - (1%)

  Fly     6 KVFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDDEM 70
            :||||.|||..:|:|:.:|||||.:.:|:|:||::::|.:|:: :||:||.|.|.|||||||.::
Mouse     8 RVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLK-DRKVFVTLTCAFRYGREDLDV 71

  Fly    71 IGLRFQKELTLVSQQVCPPQKQDIQ-LTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKASD 134
            :||.|:|:|.:.:.|..||.....: .|::|:|||||||.:|:||...:|.:.|.||.||....|
Mouse    72 LGLSFRKDLFIATYQAFPPMPNPPRPPTRLQDRLLKKLGQHAHPFFFTIPQNLPCSVTLQPGPED 136

  Fly   135 ESQPCGVQYFVKIFTGDSDCDRSHRRSTINLGIRKVQYAPTKQGIQPCTVVRKDFLLSP-GELEL 198
            ..:.|||.:.::.|...|..::||:|:::.|.|||||:||...|.||.....:.||:|. ..|.|
Mouse   137 TGKACGVDFEIRAFCAKSIEEKSHKRNSVRLIIRKVQFAPETPGPQPSAETTRHFLMSDRRSLHL 201

  Fly   199 EVTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCPL 263
            |.:|||:||:|||.::||:.|.|||.|.||||:..|:|..|:.||...|::..:|.:|..:  .:
Mouse   202 EASLDKELYYHGEPLNVNVHVTNNSAKTVKKIRVSVRQYADICLFSTAQYKCPVAQLEQDD--QV 264

  Fly   264 NPGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIASQDARDAFGIIVSYAVKVKL 328
            :|.|:..||..:.|.|..|.::.|:|::|.:|.:||.|||:|::.....::..||:|||.|||||
Mouse   265 SPSSTFCKVYTITPLLSDNREKRGLALDGQLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKL 329

  Fly   329 FLGALGGELCAELPFILMHPKP 350
            .: :.||::..||||:||||||
Mouse   330 VV-SRGGDVSVELPFVLMHPKP 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arr1	NP_476681.1	Arrestin_N	17..173	CDD:451447	67/156 (43%)
		Arrestin_C	192..350	CDD:214976	68/158 (43%)
Arrb2	NP_001258287.1	Arrestin_N	19..175	CDD:451447	67/156 (43%)
		Arrestin_C	199..350	CDD:214976	67/153 (44%)