DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arr1 and Arr3

DIOPT Version :9

Sequence 1:	NP_001246073.1	Gene:	Arr1 / 35078	FlyBaseID:	FBgn0000120	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001177922.1	Gene:	Arr3 / 171107	RGDID:	621385	Length:	381	Species:	Rattus norvegicus

Alignment Length:	364	Identity:	151/364 - (41%)
Similarity:	227/364 - (62%)	Gaps:	12/364 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VFKKCSPNNMITLYMNRRDFVDSVTQVEPIDGIIVLDDEYVRQNRKIFVQLVCNFRYGREDDEMI 71
            ||||.|.|...::|:.:|||||.|..||||||:|::|.||:: .||:||:|.|.|||||:|.::|
  Rat     4 VFKKTSSNGKFSIYLGKRDFVDDVDTVEPIDGVILVDPEYLK-GRKMFVRLTCAFRYGRDDLDVI 67

  Fly    72 GLRFQKELTLVSQQVCPPQKQDIQ--LTKMQERLLKKLGSNAYPFVMQMPPSSPASVVLQQKASD 134
            ||.|:|:|.:.::||.|.:...||  ||.:|||||.|||.|||||.:||..:.|.||.||....|
  Rat    68 GLTFRKDLYVQTKQVAPAEPTSIQGPLTALQERLLHKLGVNAYPFTLQMVANLPCSVTLQPGPED 132

  Fly   135 ESQPCGVQYFVKIFTGDSDCDRSHRRSTINLGIRKVQYAPTKQGIQPCTVVRKDFLLSPGELELE 199
            ..:||||.:.||.|..::..::..:..::.|.:||||::..:.|..|.....:.|.||...|:|:
  Rat   133 SGKPCGVDFEVKSFCAENLEEKISKSDSVQLVVRKVQFSALEPGPGPWAQTIRSFFLSSQPLQLQ 197

  Fly   200 VTLDKQLYHHGEKISVNICVRNNSNKVVKKIKAMVQQGVDVVLFQNGQFRNTIAFMETSEGCPLN 264
            ..:|:::::|||.|||::.:.|.:|||:::||..|.|..||||:...::..|:...|.:|....|
  Rat   198 AWMDREVHYHGEAISVHVSINNYTNKVIRRIKIAVIQITDVVLYSLDKYTKTVFIREFTETVAAN 262

  Fly   265 PGSSLQKVMYLVPTLVANCDRAGIAVEGDIKRKDTALASTTLIASQDARDAFGIIVSYAVKVKLF 329
              ||..:...:.|.|.||..:.|:|::|.:|.:||.|||:|::.....::..||:|||.|||.|.
  Rat   263 --SSFSQTFAVTPLLAANRQKQGLALDGKLKHEDTNLASSTILRPGMNKELLGILVSYKVKVNLM 325

  Fly   330 L---GALGG----ELCAELPFILMHPKPSRKAQLEAEGS 361
            :   |.|||    ::..|||.||:||||....:..|..|
  Rat   326 VSYGGILGGLPASDVGVELPLILIHPKPPHGERAVATSS 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arr1	NP_001246073.1	Arrestin_N	17..173	CDD:304627	75/157 (48%)
Arr1	NP_001246073.1	Arrestin_C	192..350	CDD:214976	62/164 (38%)
Arr3	NP_001177922.1	Arrestin_N	14..171	CDD:278754	75/157 (48%)
Arr3	NP_001177922.1	Arrestin_C	190..353	CDD:214976	62/164 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D340461at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920