DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rdo and LRX1

DIOPT Version :9

Sequence 1:NP_001286024.1 Gene:rdo / 35077 FlyBaseID:FBgn0243486 Length:757 Species:Drosophila melanogaster
Sequence 2:NP_172668.1 Gene:LRX1 / 837756 AraportID:AT1G12040 Length:744 Species:Arabidopsis thaliana


Alignment Length:626 Identity:115/626 - (18%)
Similarity:194/626 - (30%) Gaps:222/626 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   172 RNFF----MLSRLKYLDLSGNPLQDLQPDVFRDVPELKVLKCRNCQLKKI--------------- 217
            |:.|    :||.:.:|.:..:  .|.:.|:..|:...|.||..|.:|::.               
plant     7 RSLFLFTLLLSSVCFLQIKAD--HDDESDLGSDIKVDKRLKFENPKLRQAYIALQSWKKAIFSDP 69

  Fly   218 ----------------------NPQMYNLLPLLSELDLGRNEFKFLDKDEFRDVKRLTKVLLDGN 260
                                  :|. |....:::.:||...:.......|...:..|....::.|
plant    70 FNFTANWNGSDVCSYNGIYCAPSPS-YPKTRVVAGIDLNHADMAGYLASELGLLSDLALFHINSN 133

  Fly   261 QLSVVVDQLFRMQKSLNHLDLSYNR-LAKVPNDSFLQLTNLTFLDLSYNKLVRLEPQSIRSLSNL 324
            :....|...|...|.|..||||.|| :.|.|. ..|.|.:|.||||.||:.....|..:      
plant   134 RFCGEVPLTFNRMKLLYELDLSNNRFVGKFPK-VVLSLPSLKFLDLRYNEFEGKIPSKL------ 191

  Fly   325 LTLNISGNVLMDLREMRETFEPLIYYFFLTCSKLFFQLIPQ------LTHLAIADM---GTMPVG 380
                               |:..:...||..::..|. ||:      ::.|.:||.   |.:|..
plant   192 -------------------FDRELDAIFLNHNRFRFG-IPKNMGNSPVSALVLADNNLGGCIPGS 236

  Fly   381 LLHPFKQLRYLNISGNSLNNTALEVIDPCRELEFLDLSRNQLHGISEDTVLRIQGIRNVRLDNN- 444
            :....|.|..|.:|.::|.......|...:::...|::.|:|.|....:|..::.:..:.:.|| 
plant   237 IGQMGKTLNELILSNDNLTGCLPPQIGNLKKVTVFDITSNRLQGPLPSSVGNMKSLEELHVANNA 301

  Fly   445 ------PLICDECHMGKLINVVRQLQWKWDTYPICFLPKSLRGAEINNLDINGLHTCLTFITDEE 503
                  |.|   |.:..|.|......:.....|||      ..:.:.::.:||...|:|.:..:.
plant   302 FTGVIPPSI---CQLSNLENFTYSSNYFSGRPPIC------AASLLADIVVNGTMNCITGLARQR 357

  Fly   504 QNAASTSYNFLEHGGLNTLAILGGIIFVLIAVIILSLVACFSKNRARYYTREDHLNGSESKCLEK 568
            .:...:|                    :|...:..|...|::                       
plant   358 SDKQCSS--------------------LLARPVDCSKFGCYN----------------------- 379

  Fly   569 NLEATTITTLGNGSSPTTTTTLTLATSPAAPNGPKTNGQGLSLSPANGSTPVHGISDDKGKEINF 633
                                    ..||..|                                  
plant   380 ------------------------IFSPPPP---------------------------------- 386

  Fly   634 TFPVDDRVCTIDE---LMPSPPPPPQQHPHPNMGSLMYSVSHSPNSATTLAAVAAAATVIPPGAP 695
            ||.:...|.|:..   :..||||||.....|.:.:  ||....|:|     .::.:.....|..|
plant   387 TFKMSPEVRTLPPPIYVYSSPPPPPSSKMSPTVRA--YSPPPPPSS-----KMSPSVRAYSPPPP 444

  Fly   696 SHSSM----------PTPTPTPAEAVVVVLPPPPL----PP 722
            .:|.|          |.|:|:|....|...||||.    ||
plant   445 PYSKMSPSVRAYPPPPPPSPSPPPPYVYSSPPPPYVYSSPP 485

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rdoNP_001286024.1 leucine-rich repeat 84..107 CDD:275380
leucine-rich repeat 108..131 CDD:275380
LRR_8 131..190 CDD:290566 5/21 (24%)
leucine-rich repeat 132..155 CDD:275380
LRR_RI 151..422 CDD:238064 61/300 (20%)
leucine-rich repeat 156..179 CDD:275380 3/10 (30%)
LRR_8 178..262 CDD:290566 17/120 (14%)
leucine-rich repeat 180..203 CDD:275380 4/22 (18%)
leucine-rich repeat 204..251 CDD:275380 10/83 (12%)
leucine-rich repeat 252..275 CDD:275380 4/22 (18%)
LRR_8 274..334 CDD:290566 20/60 (33%)
leucine-rich repeat 276..299 CDD:275380 11/23 (48%)
LRR_4 298..342 CDD:289563 8/43 (19%)
leucine-rich repeat 300..323 CDD:275380 8/22 (36%)
leucine-rich repeat 388..411 CDD:275380 5/22 (23%)
LRX1NP_172668.1 PLN00113 58..>337 CDD:215061 61/315 (19%)
leucine-rich repeat 98..120 CDD:275380 3/21 (14%)
leucine-rich repeat 149..172 CDD:275380 11/23 (48%)
leucine-rich repeat 173..193 CDD:275380 8/44 (18%)
leucine-rich repeat 194..220 CDD:275380 5/26 (19%)
leucine-rich repeat 221..242 CDD:275380 5/20 (25%)
leucine-rich repeat 244..267 CDD:275380 5/22 (23%)
leucine-rich repeat 268..291 CDD:275380 5/22 (23%)
leucine-rich repeat 292..315 CDD:275380 5/25 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 98 1.000 Inparanoid score I2198
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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