DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdo and AT4G18670

DIOPT Version :9

Sequence 1:	NP_001286024.1	Gene:	rdo / 35077	FlyBaseID:	FBgn0243486	Length:	757	Species:	Drosophila melanogaster
Sequence 2:	NP_193602.4	Gene:	AT4G18670 / 827601	AraportID:	AT4G18670	Length:	857	Species:	Arabidopsis thaliana

Alignment Length:	649	Identity:	129/649 - (19%)
Similarity:	204/649 - (31%)	Gaps:	192/649 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 NLADNSIVELVQRNFFMLSRLKYLDLSGNPLQDLQPDVFRDVPELK------------VLKCRN- 211
            :|:||.:..:.||. .:..|.::.|...|  .|:.|.:..:.|.|:            :|...|
plant    37 DLSDNEVRLITQRQ-LLYFRDEFGDRGEN--VDVDPSLVFENPRLRNAYIALQAWKQAILSDPNN 98

  Fly   212 ----------CQLKKI--NPQMYN-LLPLLSELDLGRNEFKFLDKDEFRDVKRLTKVLLDGNQLS 263
                      |....:  .|.:.| .:..::.:||...:.......|...:..|....::.|:..
plant    99 FTTNWIGSDVCSYTGVYCAPALDNRRIRTVAGIDLNHADIAGYLPQELGLLTDLALFHINSNRFC 163

  Fly   264 VVVDQLFRMQKSLNHLDLSYNRLAKVPNDSFLQLTNLTFLDLSYNKLVRLEPQSIRSLSNLLTLN 328
            ..|...|...|.|..||||.||.|.:.....|||.:|.||||.:|:.....|
plant   164 GTVPHRFNRLKLLFELDLSNNRFAGIFPTVVLQLPSLKFLDLRFNEFEGPVP------------- 215

  Fly   329 ISGNVLMDLREMRETFEPLIYYFFLTCSKLFFQLIPQLTHLAIADMGTMPVGL------------ 381
                        ||.|...:...|:..::..|:| |.       ::|..||.:
plant   216 ------------RELFSKDLDAIFINHNRFRFEL-PD-------NLGDSPVSVIVVANNHFHGCI 260

  Fly   382 ---LHPFKQLRYLNISGNSLNNTALEVIDPCRELEFLDLSRNQLHGISEDTVLRIQGIRNVRLDN 443
               |...:.|..:....|..|:.....|...:.:...|.|.|:|.|....::..:..:..:.:.:
plant   261 PTSLGDMRNLEEIIFMENGFNSCLPSQIGRLKNVTVFDFSFNELVGSLPASIGGMVSMEQLNVAH 325

  Fly   444 N----PLICDECHMGKLINVVRQLQWKWDTYPICF-LPKSLRGAEINNLDINGLHTCLTFITDEE 503
            |    .:....|.:.:|.|......:.....|:|. ||           ..:....||.....:.
plant   326 NRFSGKIPATICQLPRLENFTFSYNFFTGEPPVCLGLP-----------GFDDRRNCLPARPAQR 379

  Fly   504 ---QNAASTSYNFLEHGGLNTLAILGGIIFVLIAVIILSLVACFSKNRARYY-----TREDHLNG 560
               |.||.:|...::.|..                      .|....|....     |.......
plant   380 SPGQCAAFSSLPPVDCGSF----------------------GCGRSTRPPVVVPSPPTTPSPGGS 422

  Fly   561 SESKCLEKNLEATT-----------------------ITTLGNGSSPTTTTTLTLATSPAAPNGP 602
            ..|..:..:...|.                       .||...||.||:.||.|...||  |:.|
plant   423 PPSPSISPSPPITVPSPPTTPSPGGSPPSPSIVPSPPSTTPSPGSPPTSPTTPTPGGSP--PSSP 485

  Fly   603 KTNGQGLSLSPANGSTPVHGISDDKGKEINFTFPVDDRVCTIDELMPSPPPPPQQHPHPNMGSLM 667
            .|...|.| .|::.:||..|.|....                    |:.|.|....|.|
plant   486 TTPTPGGS-PPSSPTTPTPGGSPPSS--------------------PTTPSPGGSPPSP------ 523

  Fly   668 YSVSHSPNSATTLAAVAAAATVIPPGAPSHSSMPTPT------PTPAEAVVVVLPPPPLPPQQH 725
             |:|.||    .:...:..:|...||:|...|.|||:      |||:      .||.|:.|.|:
plant   524 -SISPSP----PITVPSPPSTPTSPGSPPSPSSPTPSSPIPSPPTPS------TPPTPISPGQN 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdo	NP_001286024.1	leucine-rich repeat	84..107	CDD:275380
		leucine-rich repeat	108..131	CDD:275380
		LRR_8	131..190	CDD:290566	8/29 (28%)
		leucine-rich repeat	132..155	CDD:275380
		LRR_RI	151..422	CDD:238064	61/302 (20%)
		leucine-rich repeat	156..179	CDD:275380	5/18 (28%)
		LRR_8	178..262	CDD:290566	17/109 (16%)
		leucine-rich repeat	180..203	CDD:275380	4/22 (18%)
		leucine-rich repeat	204..251	CDD:275380	9/72 (13%)
		leucine-rich repeat	252..275	CDD:275380	4/22 (18%)
		LRR_8	274..334	CDD:290566	19/59 (32%)
		leucine-rich repeat	276..299	CDD:275380	11/22 (50%)
		LRR_4	298..342	CDD:289563	7/43 (16%)
		leucine-rich repeat	300..323	CDD:275380	7/22 (32%)
		leucine-rich repeat	388..411	CDD:275380	4/22 (18%)
AT4G18670	NP_193602.4	LRRNT_2	84..116	CDD:285463	3/31 (10%)
		LRR_8	152..208	CDD:290566	21/55 (38%)
		leucine-rich repeat	152..175	CDD:275380	4/22 (18%)
		leucine-rich repeat	176..199	CDD:275380	11/22 (50%)
		leucine-rich repeat	200..222	CDD:275380	10/46 (22%)
		leucine-rich repeat	223..243	CDD:275380	4/27 (15%)
		leucine-rich repeat	246..269	CDD:275380	2/22 (9%)
		LRR_8	268..328	CDD:290566	10/59 (17%)
		leucine-rich repeat	270..293	CDD:275380	4/22 (18%)
		leucine-rich repeat	294..317	CDD:275380	5/22 (23%)
		leucine-rich repeat	318..341	CDD:275380	2/22 (9%)
		Extensin_2	815..>856	CDD:252669
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I2198
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050