DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rdo and RLP19

DIOPT Version :9

Sequence 1:	NP_001286024.1	Gene:	rdo / 35077	FlyBaseID:	FBgn0243486	Length:	757	Species:	Drosophila melanogaster
Sequence 2:	NP_179112.1	Gene:	RLP19 / 815997	AraportID:	AT2G15080	Length:	983	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	121/499 - (24%)
Similarity:	191/499 - (38%)	Gaps:	89/499 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 LDVDVKVIIIRGPRNSITIGPALRQFMKLEILRITD-SNLPAIG--AESFWGLKYLRILDLSKNN 117
            :::|:....:||..||   ..:|.:..:|..|...| ||...||  ..|...|..|..||||:|:
plant    86 IELDLSFSCLRGQLNS---NSSLFRLPQLRFLTTLDLSNNDFIGQIPSSLETLSNLTTLDLSRNH 147

  Fly   118 ITNITENNFRGQDNLLELDLSKNKVLRMASSTFRHLTDLRRLNLADNSIVELVQRNFFMLSRLKY 182
            .:....::.....:|:.:|.|.|.......|:..:|:.|...||:.|:....|..:...||.|..
plant   148 FSGRIPSSIGNLSHLIFVDFSHNNFSGQIPSSLGYLSHLTSFNLSYNNFSGRVPSSIGNLSYLTT 212

  Fly   183 LDLSGNPLQDLQPDVFRDVPE--------LKVLKCRNCQLKKINPQMYNLLPLLSELDLGRNEFK 239
            |.||.|       ..|.::|.        ..::...|..:.||...:.||..|.| :||.:|.|.
plant   213 LRLSRN-------SFFGELPSSLGSLFHLTDLILDTNHFVGKIPSSLGNLSHLTS-IDLHKNNFV 269

  Fly   240 FLDKDEFRDVKRLTKVLLDGNQLSVVVDQLFRMQKSLNHLDLSYNRLAKVPNDSFLQLTNLTFLD 304
            ........::..||..:|..|.:...:...|.....|:.|::..|:|:.....:.|.|..|:.|.
plant   270 GEIPFSLGNLSCLTSFILSDNNIVGEIPSSFGNLNQLDILNVKSNKLSGSFPIALLNLRKLSTLS 334

  Fly   305 LSYNKLVRLEPQSIRSLSNLLTLNISGNVLMDLREMRETFEPLIYYFFLTCSKLFFQLIPQLTHL 369
            |..|:|....|.::.|||||        .|.|..|...| .||       .|.||  .||.|..:
plant   335 LFNNRLTGTLPSNMSSLSNL--------KLFDATENHFT-GPL-------PSSLF--NIPSLKTI 381

  Fly   370 AIAD---MGTMPVGLLHPFKQLRYLNISGNSLNNTALEVIDPCRELEFLDLSRNQLHGISEDTVL 431
            .:.:   .|::..|.:..:..|..|.:..|:........|.....|:.||||.....|:.:.|:.
plant   382 TLENNQLNGSLGFGNISSYSNLTVLRLGNNNFRGPIHRSISKLVNLKELDLSNYNTQGLVDFTIF 446

  Fly   432 -RIQGIRNVRLDNNPLICDECHMGKLINVVRQLQWKWDTYPICFLPKSLRGAEINNLDINGLHTC 495
             .::.|..:.|.         |:.....:        |.|.|....|.|     :.||::|.|..
plant   447 SHLKSIEYLNLS---------HLNTTTTI--------DMYEILSSFKLL-----DTLDLSGSHVS 489

  Fly   496 LTFITDEEQNAASTSYNFLEHGGLNTLAILGGIIFVLIAVIILS 539
            .|       |.:|.|.:.|                |||:.:.||
plant   490 TT-------NKSSLSNSSL----------------VLISQLYLS 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdo	NP_001286024.1	leucine-rich repeat	84..107	CDD:275380	9/25 (36%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		LRR_8	131..190	CDD:290566	18/58 (31%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		LRR_RI	151..422	CDD:238064	71/281 (25%)
		leucine-rich repeat	156..179	CDD:275380	6/22 (27%)
		LRR_8	178..262	CDD:290566	23/91 (25%)
		leucine-rich repeat	180..203	CDD:275380	6/22 (27%)
		leucine-rich repeat	204..251	CDD:275380	11/46 (24%)
		leucine-rich repeat	252..275	CDD:275380	5/22 (23%)
		LRR_8	274..334	CDD:290566	17/59 (29%)
		leucine-rich repeat	276..299	CDD:275380	6/22 (27%)
		LRR_4	298..342	CDD:289563	14/43 (33%)
		leucine-rich repeat	300..323	CDD:275380	8/22 (36%)
		leucine-rich repeat	388..411	CDD:275380	4/22 (18%)
RLP19	NP_179112.1	PLN00113	3..>646	CDD:331614	121/499 (24%)
		leucine-rich repeat	114..137	CDD:275380	8/22 (36%)
		leucine-rich repeat	138..161	CDD:275380	6/22 (27%)
		leucine-rich repeat	162..185	CDD:275380	6/22 (27%)
		leucine-rich repeat	186..209	CDD:275380	6/22 (27%)
		leucine-rich repeat	210..233	CDD:275380	7/29 (24%)
		leucine-rich repeat	234..257	CDD:275380	5/22 (23%)
		leucine-rich repeat	258..281	CDD:275380	6/23 (26%)
		leucine-rich repeat	282..305	CDD:275380	5/22 (23%)
		leucine-rich repeat	306..329	CDD:275380	6/22 (27%)
		leucine-rich repeat	330..351	CDD:275380	6/20 (30%)
		leucine-rich repeat	354..377	CDD:275380	11/40 (28%)
		leucine-rich repeat	378..402	CDD:275380	3/23 (13%)
		leucine-rich repeat	403..424	CDD:275380	4/20 (20%)
		leucine-rich repeat	427..451	CDD:275380	7/23 (30%)
		leucine-rich repeat	452..477	CDD:275380	6/41 (15%)
		leucine-rich repeat	507..526	CDD:275380	2/4 (50%)
		leucine-rich repeat	527..550	CDD:275380
		leucine-rich repeat	551..574	CDD:275380
		leucine-rich repeat	575..604	CDD:275380
		PLN00113	<604..692	CDD:331614
		leucine-rich repeat	605..630	CDD:275380
		leucine-rich repeat	631..655	CDD:275380
		PLN00113	<656..739	CDD:331614
		leucine-rich repeat	656..676	CDD:275380
		leucine-rich repeat	677..700	CDD:275380
		leucine-rich repeat	701..722	CDD:275380
		leucine-rich repeat	723..795	CDD:275380
		leucine-rich repeat	796..819	CDD:275380
		PLN00113	<808..962	CDD:331614
		leucine-rich repeat	820..843	CDD:275380
		leucine-rich repeat	844..867	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000