Protein Alignment rdo and lrrc15

DIOPT Version :10

• Sequence 1: NP_001286024.1
• Gene: rdo / 35077
• FlyBaseID: FBgn0243486
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: NP_001074151.1
• Gene: lrrc15 / 791200
• ZFINID: ZDB-GENE-031113-8
• Length: 564
• Species: Danio rerio
• Alignment Length: 628
• Identity: 144/628 - (22%)
• Similarity: 254/628 - (40%)
• Gaps: 127/628 - (20%)

  Fly     5 WLLFSLCIMPAMFSNTKRKCPTECQCSMDDLDRYQAICTKGGLNSLLSPNELDVDVKVIIIRGPR 69
            :::..:|.|.|:.|:    ||..|||.:..:     :|.             ...||.|.:..|.
Zfish     6 FVIIGMCAMKAVASS----CPESCQCQVTKI-----VCQ-------------GFSVKEIPLPMPP 48

  Fly    70 NSITIGPALRQFMKLEILRITDSNLPAIGAESFWGLKYLRILDLSKN-NITNITENNFRGQDNLL 133
            .             :..|.|:::::.::....|........|.::|| |||.:..:.|....||.
Zfish    49 T-------------INALVISNTSIQSLKPSDFQTFAETLTLFVAKNSNITEVEPHTFDQAFNLN 100

  Fly   134 ELDLSKNKVLRMASSTFRHLTDLRRLNLADNSIVELVQRNFFMLSRLKYLDLSGNPLQDLQPDVF 198
            .|..|...:..:..:.|::||.|..|.|:.|.:..|.......|:.:..||||.|.|..|..|.|
Zfish   101 ALGFSGTMLTSLPDNLFQNLTALTTLTLSGNKLEVLPSSLLTPLANVNKLDLSKNLLSSLSEDAF 165

  Fly   199 RDVPELKVLKCRNCQLKKINPQMYNLLPLLSELDLGRNEFKFLDKDEFRDVKRLTKVLLDGNQLS 263
            |.:.:|::|..:...:|:::...:..|..|..|.|.:|:...:....|.|:..|..:.|..|::.
Zfish   166 RGLDQLEMLMLQRNSIKQLHSSTFQGLSHLRSLFLQQNQLTDIPAGLFDDLVNLEVLHLQDNKIE 230

  Fly   264 VVVDQLFRMQKSLNHLDLSYNRLAKVPNDSFLQLTNLTFLDLSYNKLVRLEPQSIRSLS------ 322
            .:...||...::|..|.||.|||:.:|:..||.|.|||.:.|..|:|.||.|::..:::
Zfish   231 QLPANLFAKVQNLKKLYLSSNRLSLLPSGIFLSLPNLTHISLYDNRLSRLMPETFGTMALQELWL 295

  Fly   323 --NLLTLNISGNVLMDLREMRETFEPLIYYFFLTCSKLFFQLIPQ-----LTHLAIADMGT---- 376
              |||| ::..||..:|..:|          .|..|:...|.|..     |..|....:.|
Zfish   296 YDNLLT-HLEENVFSNLTNIR----------LLVISRNRIQYISPGAFNGLKELKEVSLHTNRLT 349

  Fly   377 -MPVGLLHPFKQLRYLNISGNSLNNTALEVIDPCRELEFLDLSRNQLHGISEDTVLRIQGIRNVR 440
             :..|:......|..::|..|.:....::::|....|..|::..|.|..:.:|.:..:..:.||.
Zfish   350 NIEPGIFRGLPNLANISIENNQIKQIPIQLLDGVSRLSLLEMQNNSLQNLPKDFLNTLSIVENVI 414

  Fly   441 LDNNPLICDE----------CHMGKLINVVRQLQWKWDTYPICFLPKSLRGAEINNL---DI--N 490
            |..||..||:          .|..|:.|:         :..:|..|..|.|..:..|   ||  .
Zfish   415 LHENPWRCDQDIIPFWGWLSQHSEKVKNL---------SLVMCSSPPPLNGRNVRELIEDDIMVQ 470

  Fly   491 GLHTCLTFITDEEQNAASTS-----YNFL--------EHGG--------LNTLAILGGIIFVLIA 534
            .:.|..|..|......||.:     .||.        :.||        .:.|.|   |:.::..
Zfish   471 EMTTMTTVDTSSHNTPASETKRPPDSNFTTISDEKEDQSGGDAAGQGLSKDKLII---IVAIICT 532

  Fly   535 VIILSLVAC--FSKNRARYYTREDHLNGSESKCLEKNLEATTI 575
            .:::|:::|  :.||:          .|||:  |:::.:...:
Zfish   533 AVVVSIISCVLWRKNK----------RGSEN--LDRHRKTNAV 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdo	NP_001286024.1	LRR	69..>446	CDD:443914	97/395 (25%)
		leucine-rich repeat	84..107	CDD:275380	3/22 (14%)
		leucine-rich repeat	108..131	CDD:275380	7/23 (30%)
		leucine-rich repeat	132..155	CDD:275380	5/22 (23%)
		leucine-rich repeat	156..179	CDD:275380	6/22 (27%)
		leucine-rich repeat	180..203	CDD:275380	10/22 (45%)
		leucine-rich repeat	204..251	CDD:275380	10/46 (22%)
		leucine-rich repeat	252..275	CDD:275380	5/22 (23%)
		leucine-rich repeat	276..299	CDD:275380	11/22 (50%)
		leucine-rich repeat	300..323	CDD:275380	8/30 (27%)
		leucine-rich repeat	388..411	CDD:275380	4/22 (18%)
lrrc15	NP_001074151.1	LRRNT	21..48	CDD:214470	9/44 (20%)
		leucine-rich repeat	53..73	CDD:275380	3/19 (16%)
		LRR	74..418	CDD:443914	93/354 (26%)
		leucine-rich repeat	171..194	CDD:275380	4/22 (18%)
		leucine-rich repeat	195..218	CDD:275380	6/22 (27%)
		leucine-rich repeat	219..242	CDD:275380	5/22 (23%)
		leucine-rich repeat	243..266	CDD:275380	11/22 (50%)
		leucine-rich repeat	267..289	CDD:275380	8/21 (38%)
		leucine-rich repeat	290..313	CDD:275380	7/23 (30%)
		leucine-rich repeat	314..337	CDD:275380	6/32 (19%)
		leucine-rich repeat	338..361	CDD:275380	3/22 (14%)
		leucine-rich repeat	362..385	CDD:275380	4/22 (18%)
		LRRCT	418..467	CDD:214507	12/57 (21%)