DRSC/TRiP Functional Genomics Resources

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Protein Alignment rdo and MstProx

DIOPT Version :9

Sequence 1:NP_001286024.1 Gene:rdo / 35077 FlyBaseID:FBgn0243486 Length:757 Species:Drosophila melanogaster
Sequence 2:NP_649719.2 Gene:MstProx / 40890 FlyBaseID:FBgn0015770 Length:965 Species:Drosophila melanogaster


Alignment Length:539 Identity:109/539 - (20%)
Similarity:197/539 - (36%) Gaps:179/539 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 KCPTECQC--SMDDLDRYQAICTKGGLNSLLSPNELDVDVKVIIIRGPRNSITIGPALRQFMKLE 85
            :||..|||  .:|||                   ||::|...:             .|.|...|.
  Fly   284 ECPKLCQCLYIIDDL-------------------ELNIDCSNL-------------GLLQIPPLP 316

  Fly    86 I-------LRITDSNLPAIGAESFWGLKYLRILDLSKNNITNITENNFRGQDNLLELDLSKNKVL 143
            |       |..::::|..:...:..|.|.::.||:|:|.:||::.|:...:  |..||:|.|:::
  Fly   317 IPSYGGVKLNFSNNSLSQLPTMTLPGYKLVKRLDVSRNRLTNLSINHLPAK--LDYLDVSFNEII 379

  Fly   144 RMASST-----------------------------FRHLTDLRRLNLAD------NSIVELV--- 170
            .|.:..                             ||||..:.|:..|:      :|:.||.   
  Fly   380 NMGNDVIKYLRTVPIFKQTGNQWTIHCDDKPLLNFFRHLKLIIRMKSAEMKPMFLHSLTELPKGF 444

  Fly   171 --------------QRNFFMLSRLKYLDLSGNPLQDL----------------------QPDVF- 198
                          ::.:::::..:.|......|.:|                      :.|:| 
  Fly   445 LKFLGKHFIWLGVRKQEYYLINEEQLLQSMHRKLNNLNTIMSIYKYMEWLHRKLIFVNREYDLFY 509

  Fly   199 -RDVPELKVLKCRNCQLKKINPQMYNLLPLLSELDLGRNEFKFLDKDEFRDVKRLTKVLLDGNQL 262
             |.:......||..|         |:...|:.::|. ||:|.:    .|.|:......|:....:
  Fly   510 IRQMAAPCPHKCECC---------YSRDSLILKIDC-RNKFVY----NFPDIVARNSRLMGKQNM 560

  Fly   263 SVVVDQLFRMQKSLNHLDLSYNRLAKVPNDSFLQLTNLTFLDLSYNKLVRLEPQSIRSL-SNLLT 326
            |      ..|:..|:..::|...:|.:|.:       |.||||.:|.||.|:.:.:..| .|.:.
  Fly   561 S------SPMELHLSKNNISNITIAMLPKE-------LRFLDLRFNNLVTLDDKVLSYLKKNSIK 612

  Fly   327 LNISGN----------VLMDLREMRETFEPLIYYFFLTCSKLFFQLIPQLTHLAIADMGTMPVGL 381
            ..:|||          ||..||:    .|||.|...|....:.....|.:. :...|..|.|..:
  Fly   613 TKLSGNPWNCDCKSRSVLSILRD----HEPLEYDVTLKRCNISPTDCPDVC-VCCLDNLTWPSFI 672

  Fly   382 LHPFKQLRYLNISGNSLNNTALEVIDPCRELEFLDLSRNQLHGISEDTVLRIQGIRNVRLD--NN 444
                     ::..|..|    |::......:.::||..|.|..:|:.....|:. |:::|.  :|
  Fly   673 ---------VDCRGEGL----LQMPSLSSRVTYVDLRNNNLTALSQKNRSSIEN-RSLKLHLLDN 723

  Fly   445 PLICDECHMGKLINVVRQL 463
            |..| .|:..:.||.::.:
  Fly   724 PWSC-SCNDIEKINFMKSV 741

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rdoNP_001286024.1 leucine-rich repeat 84..107 CDD:275380 5/29 (17%)
leucine-rich repeat 108..131 CDD:275380 7/22 (32%)
LRR_8 131..190 CDD:290566 16/110 (15%)
leucine-rich repeat 132..155 CDD:275380 10/51 (20%)
LRR_RI 151..422 CDD:238064 65/328 (20%)
leucine-rich repeat 156..179 CDD:275380 5/45 (11%)
LRR_8 178..262 CDD:290566 18/107 (17%)
leucine-rich repeat 180..203 CDD:275380 6/46 (13%)
leucine-rich repeat 204..251 CDD:275380 11/46 (24%)
leucine-rich repeat 252..275 CDD:275380 3/22 (14%)
LRR_8 274..334 CDD:290566 18/70 (26%)
leucine-rich repeat 276..299 CDD:275380 4/22 (18%)
LRR_4 298..342 CDD:289563 18/54 (33%)
leucine-rich repeat 300..323 CDD:275380 10/23 (43%)
leucine-rich repeat 388..411 CDD:275380 3/22 (14%)
MstProxNP_649719.2 leucine-rich repeat 325..345 CDD:275378 3/19 (16%)
leucine-rich repeat 346..367 CDD:275378 7/20 (35%)
leucine-rich repeat 563..583 CDD:275378 4/19 (21%)
leucine-rich repeat 585..610 CDD:275378 10/24 (42%)
leucine-rich repeat 611..622 CDD:275378 3/10 (30%)
TIR 823..960 CDD:214587
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4641
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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