Protein Alignment rdo and Nepn

DIOPT Version :9

• Sequence 1: NP_001286024.1
• Gene: rdo / 35077
• FlyBaseID: FBgn0243486
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: XP_006256553.1
• Gene: Nepn / 309775
• RGDID: 1307755
• Length: 512
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 126/489 - (25%)
• Similarity: 202/489 - (41%)
• Gaps: 103/489 - (21%)

  Fly     1 MLFKWLLFSLCIMPAMFSNTKRKCPTECQC-SMDDLDRYQAICTKGGLNSLLSPNELDVDVKVII 64
            :|:.:||: |.:...:.:|    ||..|.| |:..:..|:.:....|:.|
  Rat     3 LLWAFLLW-LSLSNVLGAN----CPGRCSCDSLQSVQCYRLLEVPSGIPS--------------- 47

  Fly    65 IRGPRNSITIGPALRQFMKL----EILRITDSNLPAIGAESFWGLKYLRILDLSKNNITNITENN 125
               ....:.|..:..|.::|    ::|.:.|..|.|.|.||                   |..:.
  Rat    48 ---TTRRLYISHSRIQHLQLSNLTQLLALEDFILLASGTES-------------------IENDT 90

  Fly   126 FRGQDNLLELDLSKNKVLRMASSTFRHLTDLRRLNLADNSIVELVQRNFFMLSRLKYLDLSGNPL 190
            |:....|..|:|.|||:.|:.|:.   ..:|..|.|.||||..|...:|..||.||.|:|..|.:
  Rat    91 FKTLTTLKTLELWKNKLRRVPSAL---PANLEVLKLNDNSICALHGSDFEGLSNLKVLELKNNLI 152

  Fly   191 QDLQPDVFR----------------------DVPELKVLKCRNCQLKKINPQMYNLLPLLSELDL 233
            ..|.|.:..                      .:|.||.:.....:|..|:..::..|..|..|..
  Rat   153 SSLSPSMLSSLVSLQSLLVDGNNIESVTGPLSLPNLKYMSMEKNKLHLISGNVFTSLQNLQFLSF 217

  Fly   234 GRNEFKFLDKDEFRDVKRLTKVLLDGNQLSVVVDQLFRMQKSLNHLDLSYNRLAKVPNDSFLQLT 298
            ..|   ||.|......|.|..:.::.|||.||..:..|..::|:||.||.|.|:.:  |....||
  Rat   218 SGN---FLTKIPINLPKSLLSLKMERNQLKVVRFRDMRHLENLSHLYLSENLLSSI--DGAQLLT 277

  Fly   299 NLTFLDLSYNKLVRLEPQSIRSLSNLLTLNISGNVL--------MDLREMRETFEPLIYYFFL-- 353
            |||.|:.|.|:|..|.|   |..|.|..|:.|.|.:        .|||:::        :.||
  Rat   278 NLTTLEASQNRLQMLPP---RLPSRLQKLDCSSNFIQRVTAPEFQDLRDLK--------HLFLDN 331

  Fly   354 TCSKLF----FQLIPQLTHLAIADMGTMPVGLLHPFKQLRYLNISGNSLNNTALEVIDPCRELEF 414
            ....||    .|...||::||:.....:.:.|..| |.|..|::.||::.:.|...:...::|:.
  Rat   332 NVVSLFEAGALQKCSQLSNLALEQNLLLSIPLRLP-KTLARLDLKGNAIQDMAERELRDLKQLQV 395

  Fly   415 LDLSRNQLHGISEDTVLRIQGIRNVRLDNNPLIC 448
            |:|..|::..:....:..:..:|::.||.||..|
  Rat   396 LNLRNNKISALDLKALEGLPRLRHLYLDGNPWNC 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdo	NP_001286024.1	leucine-rich repeat	84..107	CDD:275380	8/26 (31%)
		leucine-rich repeat	108..131	CDD:275380	2/22 (9%)
		LRR_8	131..190	CDD:290566	24/58 (41%)
		leucine-rich repeat	132..155	CDD:275380	8/22 (36%)
		LRR_RI	151..422	CDD:238064	87/306 (28%)
		leucine-rich repeat	156..179	CDD:275380	10/22 (45%)
		LRR_8	178..262	CDD:290566	23/105 (22%)
		leucine-rich repeat	180..203	CDD:275380	7/44 (16%)
		leucine-rich repeat	204..251	CDD:275380	11/46 (24%)
		leucine-rich repeat	252..275	CDD:275380	7/22 (32%)
		LRR_8	274..334	CDD:290566	25/59 (42%)
		leucine-rich repeat	276..299	CDD:275380	9/22 (41%)
		LRR_4	298..342	CDD:289563	19/51 (37%)
		leucine-rich repeat	300..323	CDD:275380	9/22 (41%)
		leucine-rich repeat	388..411	CDD:275380	5/22 (23%)
Nepn	XP_006256553.1	leucine-rich repeat	50..72	CDD:275380	3/21 (14%)
		leucine-rich repeat	73..96	CDD:275380	8/41 (20%)
		leucine-rich repeat	118..141	CDD:275380	10/22 (45%)
		leucine-rich repeat	142..165	CDD:275380	7/22 (32%)
		leucine-rich repeat	166..187	CDD:275380	0/20 (0%)
		leucine-rich repeat	188..211	CDD:275380	5/22 (23%)
		leucine-rich repeat	212..235	CDD:275380	8/25 (32%)
		leucine-rich repeat	236..256	CDD:275380	6/19 (32%)
		LRR_RI	<251..425	CDD:238064	53/187 (28%)
		leucine-rich repeat	257..278	CDD:275380	9/22 (41%)
		leucine-rich repeat	279..299	CDD:275380	9/22 (41%)
		LRR_8	298..358	CDD:290566	17/67 (25%)
		leucine-rich repeat	300..323	CDD:275380	6/22 (27%)
		leucine-rich repeat	324..347	CDD:275380	5/30 (17%)
		leucine-rich repeat	348..371	CDD:275380	7/23 (30%)
		LRR_8	367..426	CDD:290566	13/58 (22%)
		leucine-rich repeat	372..392	CDD:275380	4/19 (21%)
		leucine-rich repeat	393..416	CDD:275380	4/22 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243556at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010