DRSC/TRiP Functional Genomics Resources

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Protein Alignment rdo and Tlr6

DIOPT Version :9

Sequence 1:NP_001286024.1 Gene:rdo / 35077 FlyBaseID:FBgn0243486 Length:757 Species:Drosophila melanogaster
Sequence 2:NP_997487.1 Gene:Tlr6 / 305353 RGDID:1303030 Length:806 Species:Rattus norvegicus


Alignment Length:664 Identity:138/664 - (20%)
Similarity:233/664 - (35%) Gaps:259/664 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   110 ILDLSKNNITNITENNFRGQDNLLELDLSKNKVLRMASSTFRHLTDLRRLNLADNSIVELVQRNF 174
            ::|.|..|:|::.::.   ..:...|.||:|.:..:..|....|::||.|.|:.|.|..| ....
  Rat    46 VVDYSNKNLTHVPKDL---SPSTKSLSLSQNSISDLQMSDISFLSELRVLRLSHNRIRRL-DFGV 106

  Fly   175 FMLSR-LKYLDLSGNPLQDLQPDVFRDVPELKVLKCRNCQLKKINPQM--YNLLPLLSEL-DLGR 235
            |:|:| |:|||:|.|.||::.             .|....||.::...  :.:||:..|. :|.:
  Rat   107 FLLNRDLEYLDVSHNQLQNIS-------------CCPMVNLKHLDLSFNDFEVLPVYKEFGNLRK 158

  Fly   236 NEFKFLDKDEFRDVK-------RLTKVLLD------------------GNQLSVVV--DQLFRMQ 273
            ..|..|...:||.:.       .|:.||||                  .|.|.:|.  :.||.:|
  Rat   159 LSFLGLSAAKFRQLDLLPISHLHLSCVLLDLVNYQIKDGETESLQVPNTNVLHLVFHPNSLFSVQ 223

  Fly   274 -----KSLNHLDLSYNRLAKVPNDSFLQ--------------LTNLTF--LDLSYNKLVRL---- 313
                 .:|..|.||..:|    ||...|              |.|||.  ::.::...|||    
  Rat   224 VNISVNALGCLQLSNIKL----NDENCQSLIIFLSELTRGPTLLNLTLQHIETNWKCFVRLLQFL 284

  Fly   314 --EPQSIRSLSNL-LTLNISGNVL---------------------------------MDLREMRE 342
              .|....::.|| :|.:||....                                 |::|.:..
  Rat   285 WPRPVEYLNIYNLTITESISRETFIYVETVLKSLKIEHVTNQVFLFVKDALYSVFAEMNIRMLTL 349

  Fly   343 TFEPLIY---------YFFLT-------------CS--KLFFQLIPQLTHL-----------AIA 372
            :..|.|:         :.||.             ||  |....||.|...|           .::
  Rat   350 SDTPFIHMVCPEFPSTFAFLNFTQNVFTDSIFQGCSTLKRLETLILQRNGLKNLFKVALMTKTMS 414

  Fly   373 DMGTMPVGL----LHPF-------KQLRYLNISGNSLNNTALEVIDPCRELEFLDLSRNQLHGIS 426
            .:.|:.|.|    .|.:       :.:|.||:|.|.|:::....:.|  :::.|||..|::..|.
  Rat   415 SLETLDVSLNSLNSHVYDRTCAWAESIRVLNLSSNVLSDSVFRCLPP--KVKVLDLHNNRIVSIP 477

  Fly   427 ED-----------------------------TVLRI----------------QGIRNVRLDNNPL 446
            :|                             :||.|                |.||::...|||.
  Rat   478 KDVTHLQALQELNVASNFLTDLPGCGAFSSLSVLVIDHNSVSHPSSDFFQSCQNIRSITAGNNPF 542

  Fly   447 ICDECHMGKLINVV----RQLQWKW-DTYPICFLPKSLRGAEINNLDINGLHTCLTFITDEEQNA 506
            .| .|.:.:.:..:    |::...| |:|. |..|.|::|..:.:..::.| :|.|.:       
  Rat   543 RC-TCELREFVKNIGQASREVVEGWPDSYR-CDYPDSIKGTPLQDFHMSPL-SCDTIL------- 597

  Fly   507 ASTSYNFLEHGGLNTLAILGGIIFVLIAVIILSLVACF--------------SKNRARYYTREDH 557
                           |.:..|...:|:|.|..||...|              :::|||....|: 
  Rat   598 ---------------LTVTIGATLLLLAAIGASLCLYFDLPWYLRMLWQWTQTRHRARNIPLEE- 646

  Fly   558 LNGSESKCLEKNLE 571
                    |::||:
  Rat   647 --------LQRNLQ 652

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rdoNP_001286024.1 leucine-rich repeat 84..107 CDD:275380
leucine-rich repeat 108..131 CDD:275380 4/20 (20%)
LRR_8 131..190 CDD:290566 22/59 (37%)
leucine-rich repeat 132..155 CDD:275380 6/22 (27%)
LRR_RI 151..422 CDD:238064 90/408 (22%)
leucine-rich repeat 156..179 CDD:275380 9/22 (41%)
LRR_8 178..262 CDD:290566 26/112 (23%)
leucine-rich repeat 180..203 CDD:275380 8/22 (36%)
leucine-rich repeat 204..251 CDD:275380 11/56 (20%)
leucine-rich repeat 252..275 CDD:275380 11/47 (23%)
LRR_8 274..334 CDD:290566 21/82 (26%)
leucine-rich repeat 276..299 CDD:275380 9/36 (25%)
LRR_4 298..342 CDD:289563 14/85 (16%)
leucine-rich repeat 300..323 CDD:275380 6/30 (20%)
leucine-rich repeat 388..411 CDD:275380 7/22 (32%)
Tlr6NP_997487.1 leucine-rich repeat 46..64 CDD:275380 4/20 (20%)
leucine-rich repeat 65..88 CDD:275378 6/22 (27%)
LRR_8 87..144 CDD:290566 21/70 (30%)
leucine-rich repeat 89..112 CDD:275378 9/23 (39%)
leucine-rich repeat 113..133 CDD:275378 9/32 (28%)
leucine-rich repeat 134..158 CDD:275378 6/23 (26%)
leucine-rich repeat 369..385 CDD:275380 1/15 (7%)
LRR_RI <380..>500 CDD:238064 24/121 (20%)
LRR_8 388..451 CDD:290566 14/62 (23%)
leucine-rich repeat 390..415 CDD:275380 4/24 (17%)
leucine-rich repeat 416..440 CDD:275380 4/23 (17%)
leucine-rich repeat 441..462 CDD:275380 7/22 (32%)
LRR_8 461..516 CDD:290566 10/56 (18%)
leucine-rich repeat 463..485 CDD:275380 6/21 (29%)
leucine-rich repeat 486..508 CDD:275380 0/21 (0%)
leucine-rich repeat 510..531 CDD:275380 3/20 (15%)
LRRCT 540..594 CDD:214507 13/56 (23%)
TIR 652..791 CDD:214587 0/1 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4641
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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