DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rdo and Podnl1

DIOPT Version :9

Sequence 1:NP_001286024.1 Gene:rdo / 35077 FlyBaseID:FBgn0243486 Length:757 Species:Drosophila melanogaster
Sequence 2:XP_213845.6 Gene:Podnl1 / 288907 RGDID:1307753 Length:582 Species:Rattus norvegicus


Alignment Length:514 Identity:117/514 - (22%)
Similarity:192/514 - (37%) Gaps:115/514 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 RKCPTECQCSMDD-LDRYQAICTKGGLNSLLSPNELDVDVKVIIIRGPRNSITIGPALRQFMKLE 85
            |.||..|.|..|| :|     |  .||:                                     
  Rat    51 RPCPWRCSCPRDDTVD-----C--AGLD------------------------------------- 71

  Fly    86 ILRITDSNLPAIGAESFWGLKYLRILDLSKNNITNITENNFRGQDNLLELDLSKNKVLR--MASS 148
             ||:...|:          .:..|.|.|.||.:..:..|.......|..|||..|.:..  :...
  Rat    72 -LRVFPDNI----------TRAARHLSLQKNQLQELPYNELSRLSGLRTLDLHSNLISSEGLPDE 125

  Fly   149 TFRHLTDLRRLNLADNSIVELVQRNFFMLSRLKYLDLSGNPLQDLQPDVFRDVPELKVLKCRNCQ 213
            .|..||.|....:|.|.:....|   |:...|:..||:.|.:.::.|..|.:.|.|:.:...|.:
  Rat   126 AFESLTQLENFYVAHNKLSVAPQ---FLPRSLRVADLAANEVVEIFPLTFGEKPALRSVYLHNNR 187

  Fly   214 LKK--INPQMYNLLPLLSELDLGRNEFKFLDKDEFRDVKRLTKVLLDGNQLSVVVDQLFRMQKSL 276
            |:.  :.|..::....::.|.|..|:.::|.......::||.   |..|.:|.|......:|..|
  Rat   188 LRNTGLPPNTFHGSEAITTLSLSSNQLRYLPPSLPASLERLH---LQNNLISKVPRGALSLQTQL 249

  Fly   277 NHLDLSYNRLAKVPND--SFLQLTNLTFLDLSYNKLVRLEPQSIRSLSNLLTLNISGNVLMDLRE 339
            ..|.|.:|:|.....|  :|.:|::|.:||||:|:|..: |:.:.  .||..|::..|.:..:..
  Rat   250 RELYLQHNQLTDSGLDATTFSKLSSLEYLDLSHNQLATV-PEGLP--GNLTILHLGRNCIRHVEA 311

  Fly   340 MRETFEPLIYYFFLTCSKLFFQLIPQLTHLAIADMGTMPVGLLHPFKQLRYLNISGNSLNNTALE 404
            :|......:.|..|..:||              :...:|.|.|.|.:.|..|::.||     .||
  Rat   312 IRLHKAKGLRYLLLQHNKL--------------EASALPAGTLRPLRALHTLHLYGN-----RLE 357

  Fly   405 VIDPC--RELEFLDLSRNQLHGISEDTVLRIQGIRNVRLDNNPLICDECHMG--KLINVVRQLQW 465
            .:.|.  |.|:.|.:..|::..:....::..:.:..:.|..|.|.....|.|  :.:..:|.|..
  Rat   358 RVPPALPRHLQALVMPHNRVAALGARDLVSARALTELNLAYNRLASAHVHPGAFRRLRALRSLDL 422

  Fly   466 KWDTYPIC--FLPKSLRGAEINNLDINGLHTCLTFITDEEQNAASTSYNFLEHGGLNTL 522
            ..:.....  .||.|||...:..   |.|.|     .:.||.|           |||.|
  Rat   423 AGNQLSRLPEGLPASLRSLRLQR---NQLRT-----LEPEQLA-----------GLNKL 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rdoNP_001286024.1 leucine-rich repeat 84..107 CDD:275380 3/22 (14%)
leucine-rich repeat 108..131 CDD:275380 6/22 (27%)
LRR_8 131..190 CDD:290566 17/60 (28%)
leucine-rich repeat 132..155 CDD:275380 7/24 (29%)
LRR_RI 151..422 CDD:238064 69/276 (25%)
leucine-rich repeat 156..179 CDD:275380 5/22 (23%)
LRR_8 178..262 CDD:290566 19/85 (22%)
leucine-rich repeat 180..203 CDD:275380 6/22 (27%)
leucine-rich repeat 204..251 CDD:275380 8/48 (17%)
leucine-rich repeat 252..275 CDD:275380 6/22 (27%)
LRR_8 274..334 CDD:290566 20/61 (33%)
leucine-rich repeat 276..299 CDD:275380 8/24 (33%)
LRR_4 298..342 CDD:289563 12/43 (28%)
leucine-rich repeat 300..323 CDD:275380 8/22 (36%)
leucine-rich repeat 388..411 CDD:275380 7/24 (29%)
Podnl1XP_213845.6 leucine-rich repeat 64..82 CDD:275380 7/72 (10%)
leucine-rich repeat 83..106 CDD:275380 6/22 (27%)
LRR_8 84..143 CDD:290566 17/58 (29%)
leucine-rich repeat 107..132 CDD:275380 7/24 (29%)
leucine-rich repeat 133..177 CDD:275380 11/46 (24%)
LRR_8 152..214 CDD:290566 14/61 (23%)
LRR_RI 175..451 CDD:238064 71/308 (23%)
leucine-rich repeat 178..203 CDD:275380 4/24 (17%)
leucine-rich repeat 204..224 CDD:275380 4/19 (21%)
LRR_8 224..285 CDD:290566 21/63 (33%)
leucine-rich repeat 225..248 CDD:275380 7/25 (28%)
leucine-rich repeat 249..274 CDD:275380 8/24 (33%)
leucine-rich repeat 275..319 CDD:275380 13/46 (28%)
LRR_8 295..356 CDD:290566 17/79 (22%)
leucine-rich repeat 298..317 CDD:275380 3/18 (17%)
leucine-rich repeat 320..345 CDD:275380 8/38 (21%)
leucine-rich repeat 346..390 CDD:275380 11/48 (23%)
LRR_8 365..427 CDD:290566 11/61 (18%)
leucine-rich repeat 391..416 CDD:275380 5/24 (21%)
leucine-rich repeat 417..440 CDD:275380 6/22 (27%)
LRR_8 437..498 CDD:290566 13/45 (29%)
leucine-rich repeat 441..461 CDD:275380 8/38 (21%)
leucine-rich repeat 462..487 CDD:275380 1/1 (100%)
LRR_8 488..543 CDD:290566
leucine-rich repeat 509..532 CDD:275380
leucine-rich repeat 533..556 CDD:275380
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D243556at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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