| Sequence 1: | NP_001286024.1 | Gene: | rdo / 35077 | FlyBaseID: | FBgn0243486 | Length: | 757 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_067272.1 | Gene: | Tlr4 / 21898 | MGIID: | 96824 | Length: | 835 | Species: | Mus musculus |
| Alignment Length: | 680 | Identity: | 159/680 - (23%) |
|---|---|---|---|
| Similarity: | 238/680 - (35%) | Gaps: | 261/680 - (38%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 46 GLNSLLSPNELDVDVKVIIIRGPRNSITIGPALRQFMKLEILRITDS-----NLPAIGAESFWGL 105
Fly 106 KYLRILDLSKNNITNITENNFR-----GQDNLLELDLSKNKV----------LRMASSTFR---- 151
Fly 152 -----------------------HLTDLRRLNLADNSIVE-----------LVQRN--------F 174
Fly 175 FMLSRLKYLDLSGNPLQDLQPDVFRDVPE------LKVLKCRNCQLKKIN-PQMYNL-------- 224
Fly 225 -------LPLLSELDLGRNEFKFLDKDEFRDVKRLTKVLLDGNQLSVVVDQLFRMQKSLNHLDLS 282
Fly 283 YNRLAKVPNDSFLQLTNLTFLDLSYNKLVRL-EPQSIRSLSNLLTLNISGNVLMDLREMRETFEP 346
Fly 347 LIYYFFLTCSKLFFQLIPQLTHLAIADMGTMPVGLLHPFKQLRYLNISGNSL-NNTALEVIDPCR 410
Fly 411 ELEFLDLSRNQLHGIS---EDTVLRIQGIRNVRLDNNPLICDECHMGKLINVVRQLQWKWDTYPI 472
Fly 473 CF------------LPKSLRGAEINNLDINGLHTCL--------------TFITDEEQNAASTSY 511
Fly 512 NFLEHGGLNTLAILG----------GIIFV-LIAVIILSLVA---------------C--FSKNR 548
Fly 549 ARY-----YT--REDHLNGSESKCLEKNLE 571 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| rdo | NP_001286024.1 | leucine-rich repeat | 84..107 | CDD:275380 | 7/27 (26%) |
| leucine-rich repeat | 108..131 | CDD:275380 | 10/27 (37%) | ||
| LRR_8 | 131..190 | CDD:290566 | 20/114 (18%) | ||
| leucine-rich repeat | 132..155 | CDD:275380 | 7/59 (12%) | ||
| LRR_RI | 151..422 | CDD:238064 | 75/340 (22%) | ||
| leucine-rich repeat | 156..179 | CDD:275380 | 9/41 (22%) | ||
| LRR_8 | 178..262 | CDD:290566 | 22/105 (21%) | ||
| leucine-rich repeat | 180..203 | CDD:275380 | 5/22 (23%) | ||
| leucine-rich repeat | 204..251 | CDD:275380 | 16/62 (26%) | ||
| leucine-rich repeat | 252..275 | CDD:275380 | 0/22 (0%) | ||
| LRR_8 | 274..334 | CDD:290566 | 24/60 (40%) | ||
| leucine-rich repeat | 276..299 | CDD:275380 | 10/22 (45%) | ||
| LRR_4 | 298..342 | CDD:289563 | 13/44 (30%) | ||
| leucine-rich repeat | 300..323 | CDD:275380 | 8/23 (35%) | ||
| leucine-rich repeat | 388..411 | CDD:275380 | 8/23 (35%) | ||
| Tlr4 | NP_067272.1 | LRR_8 | 53..113 | CDD:290566 | |
| LRR 1 | 54..75 | ||||
| leucine-rich repeat | 58..78 | CDD:275380 | |||
| LRR 2 | 78..99 | ||||
| leucine-rich repeat | 79..102 | CDD:275380 | |||
| LRR 3 | 102..123 | 159/680 (23%) | |||
| leucine-rich repeat | 103..126 | CDD:275380 | 2/2 (100%) | ||
| LRR 4 | 126..147 | 8/30 (27%) | |||
| leucine-rich repeat | 127..150 | CDD:275380 | 8/32 (25%) | ||
| LRR_8 | 150..214 | CDD:290566 | 23/68 (34%) | ||
| LRR 5 | 150..171 | 5/24 (21%) | |||
| leucine-rich repeat | 151..175 | CDD:275380 | 7/27 (26%) | ||
| LRR 6 | 175..198 | 9/22 (41%) | |||
| leucine-rich repeat | 176..204 | CDD:275380 | 10/27 (37%) | ||
| LRR 7 | 204..224 | 6/20 (30%) | |||
| leucine-rich repeat | 205..226 | CDD:275380 | 5/20 (25%) | ||
| LRR 8 | 226..247 | 2/20 (10%) | |||
| LRR 9 | 248..269 | 2/20 (10%) | |||
| LRR 10 | 329..349 | 3/19 (16%) | |||
| leucine-rich repeat | 331..350 | CDD:275380 | 3/18 (17%) | ||
| LRR 11 | 350..370 | 1/19 (5%) | |||
| leucine-rich repeat | 351..372 | CDD:275380 | 2/20 (10%) | ||
| LRR_RI | <369..555 | CDD:238064 | 70/258 (27%) | ||
| LRR 12 | 372..392 | 8/19 (42%) | |||
| leucine-rich repeat | 373..398 | CDD:275380 | 9/46 (20%) | ||
| LRR 13 | 398..420 | 10/22 (45%) | |||
| leucine-rich repeat | 399..421 | CDD:275380 | 10/22 (45%) | ||
| LRR 14 | 421..442 | 6/20 (30%) | |||
| leucine-rich repeat | 422..446 | CDD:275380 | 8/23 (35%) | ||
| LRR 15 | 446..467 | 9/60 (15%) | |||
| leucine-rich repeat | 447..470 | CDD:275380 | 9/62 (15%) | ||
| LRR 16 | 470..490 | 7/19 (37%) | |||
| leucine-rich repeat | 471..495 | CDD:275380 | 8/23 (35%) | ||
| LRR_8 | 494..554 | CDD:290566 | 23/69 (33%) | ||
| LRR 17 | 495..516 | 10/20 (50%) | |||
| leucine-rich repeat | 496..519 | CDD:275380 | 12/22 (55%) | ||
| LRR 18 | 519..540 | 8/22 (36%) | |||
| leucine-rich repeat | 520..543 | CDD:275380 | 8/24 (33%) | ||
| LRR 19 | 543..564 | 2/28 (7%) | |||
| Interaction with SCIMP. /evidence=ECO:0000269|PubMed:28098138 | 670..835 | 9/30 (30%) | |||
| TIR | 672..813 | CDD:214587 | 9/28 (32%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG4641 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||