Protein Alignment rdo and lron-2

DIOPT Version :10

• Sequence 1: NP_001286024.1
• Gene: rdo / 35077
• FlyBaseID: FBgn0243486
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: NP_505402.1
• Gene: lron-2 / 179309
• WormBaseID: WBGene00022789
• Length: 575
• Species: Caenorhabditis elegans
• Alignment Length: 680
• Identity: 142/680 - (20%)
• Similarity: 242/680 - (35%)
• Gaps: 203/680 - (29%)

  Fly    23 KCPT---ECQCSMDDLDRYQAICTKGGLNSLLSPNELDVDVKVIIIRGPRNSITIGPALRQFMKL 84
            :||.   .|:|:....:....||...|  ||                  :|:|....|.|. :.:
 Worm    18 QCPALSGACRCAPSVYEPVAIICQNAG--SL------------------QNAIQAIQAARD-IPI 61

  Fly    85 EILRITDSNLPAIGAESFWGLKYLRILDLSKNNITNITENNFRGQ--DNLLELDLSKNKVLRMAS 147
            :.|.|.|:.:|.|.|.:|.....||:: |::|.:.||.:..|.|.  |:|:||||:.|.:.::..
 Worm    62 DSLTILDTAIPTIPANAFQSFTILRLV-LNRNTLQNIDDQAFNGPLLDSLIELDLNDNNLGQIPQ 125

  Fly   148 STFRHLTDLRRLNLADNSIVELVQRNFFML-SR--LKYLDLSGNPLQD----------------- 192
            :....|.:||:|.|..|.|.:|....|... ||  |..|:|:||.|.|
 Worm   126 TGIPRLRNLRKLYLNRNRINQLSSTAFNAFESRDLLLKLELAGNRLTDATLGDATVFRPLTLLQE 190

  Fly   193 --LQPDVFRDVPELKVLKCR------NCQLKKINPQMYNLL--PLLSELDLGRNEFKFLDKDEFR 247
              |:.:....:|...::..|      |..|..||......|  |:||.|.|..|....:....|:
 Worm   191 LSLETNSLTSIPSSALVNQRNTLTNLNLGLNSINEVPVGALDFPVLSSLSLEFNGITVIPPQAFQ 255

  Fly   248 DVKRLTKVLLDGNQLSVVVDQLFRMQKSLNHLDLSYNRLAKVPNDSFLQLTNLTFLDLS------ 306
            .|..|..:.:.||:......::||....|..|.:....::.:||::|:.:.||..|::|
 Worm   256 GVPNLQFLYMTGNKFPSWAPEMFRYITQLKTLGIGETPISVIPNNAFMHIPNLIRLEMSEAAVDT 320

  Fly   307 ------------------YNKLVRLEPQSIRSLSNLLTLNISGNVLMDLREMRETFEPLIYYFFL 353
                              .|:|.::.......|::|.::::.||.:       :..:|
 Worm   321 IERGAFQRTPQIQAIVLNKNRLSQVRADFFEGLNDLYSIDLQGNRI-------DNVQP------- 371

  Fly   354 TCSKLFFQLIPQLTHLAIAD--MGTMPVGLLHPFKQLRYLNISGNSLNNTALEVIDPCRELEFLD 416
                |.|..:|.::||.|:.  :.|||            .|:..||                ||.
 Worm   372 ----LGFANLPAISHLDISYNLLQTMP------------SNVFQNS----------------FLP 404

  Fly   417 LSRNQLHGISEDTVLRIQGIRNVRLDNNPLICDECHMGKLINVVRQLQWKWDTYPICFLPKSLRG 481
            ...::               |.:....||..|:.           :|:|             .|.
 Worm   405 QPNDR---------------RVIYACGNPWYCNS-----------ELEW-------------FRT 430

  Fly   482 AEINNLDINGLHTCLTFITDEEQNAAST------SYNFLEHG-------GLNTLAILGGIIFVLI 533
            ...:||||:......|.:.....|....      |.:|.::.       | ..|:::|.||..:|
 Worm   431 LLRDNLDIDVEKPGCTAVCTSSPNGCPVEGTPLRSVDFCQNNEEAQPLVG-RALSMVGWIILAVI 494

  Fly   534 AVIILSLVACFSKNRARYYTREDHLNGSESK-CLEKNLEATTITTLGNGSSPTTTTTLTLATSPA 597
            ..|:|..:...:  ..||..........::: ..|:....||.|::.|  :|.:......:|.|
 Worm   495 MTILLISICLLA--MVRYGMSHQRKKQKDAEVAAEEYHHQTTATSIYN--APISVVDRPYSTVP- 554

  Fly   598 APNGPKTNGQGLSLSPANGSTPVHGISDDK 627
                           |.|...|.....||:
 Worm   555 ---------------PVNLDLPAAYTLDDR 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdo	NP_001286024.1	LRR	69..>446	CDD:443914	97/434 (22%)
		leucine-rich repeat	84..107	CDD:275380	7/22 (32%)
		leucine-rich repeat	108..131	CDD:275380	8/24 (33%)
		leucine-rich repeat	132..155	CDD:275380	7/22 (32%)
		leucine-rich repeat	156..179	CDD:275380	8/23 (35%)
		leucine-rich repeat	180..203	CDD:275380	8/41 (20%)
		leucine-rich repeat	204..251	CDD:275380	14/54 (26%)
		leucine-rich repeat	252..275	CDD:275380	5/22 (23%)
		leucine-rich repeat	276..299	CDD:275380	5/22 (23%)
		leucine-rich repeat	300..323	CDD:275380	6/46 (13%)
		leucine-rich repeat	388..411	CDD:275380	3/22 (14%)
lron-2	NP_505402.1	LRR	59..441	CDD:443914	102/467 (22%)
		leucine-rich repeat	64..84	CDD:275380	7/19 (37%)
		leucine-rich repeat	85..109	CDD:275380	8/24 (33%)
		leucine-rich repeat	110..133	CDD:275380	7/22 (32%)
		leucine-rich repeat	134..157	CDD:275380	8/22 (36%)
		leucine-rich repeat	161..187	CDD:275380	7/25 (28%)
		leucine-rich repeat	188..211	CDD:275380	2/22 (9%)
		leucine-rich repeat	213..235	CDD:275380	5/21 (24%)
		leucine-rich repeat	236..259	CDD:275380	7/22 (32%)
		leucine-rich repeat	260..283	CDD:275380	5/22 (23%)
		leucine-rich repeat	284..307	CDD:275380	5/22 (23%)
		leucine-rich repeat	308..355	CDD:275380	6/46 (13%)
		leucine-rich repeat	356..377	CDD:275380	6/38 (16%)
		leucine-rich repeat	380..400	CDD:275380	7/31 (23%)