Protein Alignment rdo and igfals

DIOPT Version :9

• Sequence 1: NP_001286024.1
• Gene: rdo / 35077
• FlyBaseID: FBgn0243486
• Length: 757
• Species: Drosophila melanogaster
• Sequence 2: XP_002940278.2
• Gene: igfals / 100489984
• XenbaseID: XB-GENE-1008441
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 589
• Identity: 159/589 - (26%)
• Similarity: 230/589 - (39%)
• Gaps: 149/589 - (25%)

  Fly    24 CPTECQCSMDDLDRYQAICTKGGLNSLLSPNELDVDVKVIIIRGPRNSITIGPALRQFMKLEILR 88
            ||..|.||.|..:.|...|:...|..:..|..                    ||.|.      |.
 Frog    35 CPPPCVCSYDYSEEYSVFCSSRNLTRVPEPPP--------------------PAARS------LW 73

  Fly    89 ITDSNLPAIGAESFWGLKYLRILDLSKNNITNITENNFRGQDNLLELDLSKNKVLRMASSTFRHL 153
            :..:||..:.|.:|..|.:|..|:|..:.:.::.:....|...|..|.|.:|.:..:|.|||.|.
 Frog    74 LDGNNLTTVQAGAFRNLSHLDFLNLQSSQVASLEQQALHGLKALAHLHLERNMIKSLAPSTFTHT 138

  Fly   154 TDLRRLNLADNSIVELVQRNFFMLSRLKYLDLSGNPLQDLQPDVFRDVPELKVLKCRNCQLKKIN 218
            .:|..|.|.:|.:.::....|..||.|.||:|..|.|..|...||.|:..|:.|.....:|..:.
 Frog   139 QNLVSLTLNNNFLTKIEDGLFSGLSNLWYLNLGWNLLVVLPDMVFHDLLNLRELVLAGNRLVYLQ 203

  Fly   219 PQMYNLLPLLSELDLGRNEFKFLDKDEFRDVKRLTKVLLDGNQLSVVVDQLFRMQKSLNHLDLSY 283
            |.::..|..|.||||..|..|.:..:.|...::..|:.|:.|.:|.|..:.|...|:|..||||:
 Frog   204 PSLFLSLGELKELDLSGNSLKGIKANVFTRQQKTHKLYLNHNHISTVAPRAFSGMKNLRWLDLSH 268

  Fly   284 NRLAKVPNDSFLQLTNLTFLDLSYNKLVRLEP--------------------------------- 315
            |||..:..|:|..|.:|..|.||.|.|..|.|
 Frog   269 NRLTALYEDTFFGLPSLNVLRLSNNSLTSLRPRIFKDLQFLVELNLGQNKIKILLERTFEGLAQL 333

  Fly   316 ----------QSIR-----SLSNLLTLNISGNVLMDLRE-------------MRET----FEPLI 348
                      |.||     .|.|:..:|:|||.|..|.|             |..:    .:|.:
 Frog   334 ELLSLNHNNVQEIRPGSFLGLLNVAVINLSGNCLKSLAEHCFKGLGKLHSLHMESSCLSHIKPQM 398

  Fly   349 YYFFLTCSKLFFQ-----------------LIP------QLTHLAIADMGTMPVGLLHPFKQLRY 390
            :....:..:||.|                 |:.      :||||.....    .||    |.|.|
 Frog   399 FAGLSSIRRLFLQNNEIVAIEDHSFTDLHGLLELDLRSNKLTHLTTRSF----TGL----KNLSY 455

  Fly   391 LNISGNSLNNTALEVIDPCRELEFLDLSRNQLHGISEDTVLRIQGIRNVRLDNNPLICDECHMGK 455
            |.:|.|.:...:.||..|.::|::||||.|||..::||..|.:..:|.:.|.||.|        |
 Frog   456 LLLSSNQILTISPEVFSPVQQLQWLDLSDNQLKALTEDIFLPLSSLRYLSLKNNCL--------K 512

  Fly   456 LINV--------VRQLQW----KWDTYPICFLPKSLRGAEINNLDINGLHTCLTFITDEEQNAAS 508
            .|:|        ::|| |    :||..  |.| |.||...:.|..|.. |  |.....|..:.||
 Frog   513 TISVNFLIPPPTMQQL-WLNGNQWDCG--CAL-KGLRDLALRNSTIVP-H--LVQSISEGDDTAS 570

  Fly   509 TSYN 512
            ..||
 Frog   571 PVYN 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdo	NP_001286024.1	leucine-rich repeat	84..107	CDD:275380	6/22 (27%)
		leucine-rich repeat	108..131	CDD:275380	4/22 (18%)
		LRR_8	131..190	CDD:290566	21/58 (36%)
		leucine-rich repeat	132..155	CDD:275380	9/22 (41%)
		LRR_RI	151..422	CDD:238064	96/358 (27%)
		leucine-rich repeat	156..179	CDD:275380	6/22 (27%)
		LRR_8	178..262	CDD:290566	27/83 (33%)
		leucine-rich repeat	180..203	CDD:275380	10/22 (45%)
		leucine-rich repeat	204..251	CDD:275380	13/46 (28%)
		leucine-rich repeat	252..275	CDD:275380	6/22 (27%)
		LRR_8	274..334	CDD:290566	29/107 (27%)
		leucine-rich repeat	276..299	CDD:275380	11/22 (50%)
		LRR_4	298..342	CDD:289563	21/104 (20%)
		leucine-rich repeat	300..323	CDD:275380	12/70 (17%)
		leucine-rich repeat	388..411	CDD:275380	8/22 (36%)
igfals	XP_002940278.2	leucine-rich repeat	69..92	CDD:275380	7/28 (25%)
		PLN00113	71..>534	CDD:215061	130/485 (27%)
		leucine-rich repeat	93..116	CDD:275380	4/22 (18%)
		leucine-rich repeat	117..140	CDD:275380	9/22 (41%)
		leucine-rich repeat	141..164	CDD:275380	6/22 (27%)
		leucine-rich repeat	165..188	CDD:275380	10/22 (45%)
		leucine-rich repeat	189..212	CDD:275380	5/22 (23%)
		leucine-rich repeat	213..236	CDD:275380	8/22 (36%)
		leucine-rich repeat	237..260	CDD:275380	6/22 (27%)
		leucine-rich repeat	261..284	CDD:275380	11/22 (50%)
		leucine-rich repeat	285..308	CDD:275380	8/22 (36%)
		leucine-rich repeat	309..332	CDD:275380	0/22 (0%)
		leucine-rich repeat	333..354	CDD:275380	3/20 (15%)
		leucine-rich repeat	357..380	CDD:275380	7/22 (32%)
		leucine-rich repeat	381..404	CDD:275380	2/22 (9%)
		leucine-rich repeat	405..428	CDD:275380	3/22 (14%)
		leucine-rich repeat	429..450	CDD:275380	5/24 (21%)
		leucine-rich repeat	453..472	CDD:275380	7/18 (39%)
		leucine-rich repeat	477..500	CDD:275380	11/22 (50%)
		leucine-rich repeat	525..537	CDD:275378	4/12 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910