DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elfless and si:ch1073-440b2.1

DIOPT Version :9

Sequence 1:	NP_001163003.1	Gene:	elfless / 35076	FlyBaseID:	FBgn0032660	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	XP_001340443.6	Gene:	si:ch1073-440b2.1 / 100000190	ZFINID:	ZDB-GENE-030131-8303	Length:	749	Species:	Danio rerio

Alignment Length:	194	Identity:	51/194 - (26%)
Similarity:	82/194 - (42%)	Gaps:	42/194 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 SQRIHNTGPTPVLAPSGLRSRLLSGSSERNPNEYYGDSDSSSSSRSIDRTPFLLEYSSDSESSSS 119
            :|:|.:...:.|....||.:.|.:.:|...|.     |..||.:..|.|        ..:::..|
Zfish   325 AQKILSHMFSSVFVNDGLATSLPACTSRIKPT-----SLLSSLNTIIPR--------DGTKAGCS 376

  Fly   120 SDSESSSTSISFDSSMSSTESSTPMG-------------HTESSDSNEDSPPNKRIKSDDEESK- 170
            .|...|.:.|. |.:...:|:...:|             .||:|..:|  ||:|::|.|...|.
Zfish   377 KDLTLSCSKIK-DGNSQLSENVNCVGLSSLFIPPVLKRKWTENSKQSE--PPSKQLKEDHVFSSA 438

  Fly   171 --KSVLP--------YNCPVCLEDVREKLPVSTNCGHVFCKACIKRAVDTGRVCPLCGVDEPEF 224
              |..:|        :.|.:|:....|  ||:|.|||.||..|::|.:|....||||..:..|:
Zfish   439 VVKRQVPLQLLDNADFECSLCMRLFYE--PVTTPCGHTFCLKCLERCLDHNPNCPLCKENLSEY 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elfless	NP_001163003.1	RING	178..217	CDD:214546	16/38 (42%)
si:ch1073-440b2.1	XP_001340443.6	RING_Ubox	146..181	CDD:327409
		TPR repeat	220..245	CDD:276809
		TPR_11	230..>329	CDD:330823	1/3 (33%)
		TPR repeat	250..280	CDD:276809
		TPR repeat	285..308	CDD:276809
		RAD18	446..>546	CDD:333230	19/57 (33%)
		RING2-HC_LONFs	453..494	CDD:319428	17/42 (40%)
		RING-HC finger (C3HC4-type)	456..493	CDD:319428	16/38 (42%)
		LON_substr_bdg	544..745	CDD:308028
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910