DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btv and Dnhd1

DIOPT Version :9

Sequence 1:	NP_001036369.3	Gene:	btv / 35073	FlyBaseID:	FBgn0023096	Length:	4236	Species:	Drosophila melanogaster
Sequence 2:	XP_008758037.1	Gene:	Dnhd1 / 690115	RGDID:	1584052	Length:	4758	Species:	Rattus norvegicus

Alignment Length:	4779	Identity:	962/4779 - (20%)
Similarity:	1689/4779 - (35%)	Gaps:	1392/4779 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 VDAWIQ--LCDSLTRLFWP-NYVKH--------PWLGDSHVPKRGQQ------FKERLSEIRSIK 317
            |.||:|  |.|::.:.|.| :.:.|        ||:...|   ||..      .|.|..:
  Rat   169 VQAWLQLDLLDAIDKAFPPDSSLLHSSSHVDCSPWMKRFH---RGPPCSACPFVKARWDQ----- 225

  Fly   318 QLYKQIATLLED---TELQ--------EMFQEQAPF------------TEFNI-FDTSSLG---- 354
            |..|::||.|..   .|||        |:..|:.|:            |:..: :::|.:|
  Rat   226 QQKKELATWLRPLTLPELQHCLGIVGAEVALEETPWLDSLSLLPLALATDIPVQYESSDIGHAEP 290

  Fly   355 ----------QNKWHKALQHFEQVLQPIDERIAAALK-----RQLH---------NHLSNPRQVI 395
                      .....|||:........:..::.:.||     :::|         .|. ||.:::
  Rat   291 APAGRKPQLASEAPEKALKRKSPRTSILRSQVKSLLKGDWSQKKIHFLYLNVASDRHF-NPYKLV 354

  Fly   396 -----------FIFSKYETL----IQRPAVLELLTIEREQFLQSLHILLQD-------LRKAMVD 438
                       :|||.:..|    ::....:.|.|..|:..|  .|.|.:.       ||||:.
  Rat   355 VVPPNKVNPEHYIFSPFGILHIHPVEGSETMSLATWHRDTAL--WHELQRIPFFKNCLLRKALT- 416

  Fly   439 SNMEPDTGHLSVICNECRWLKVVQ----HQIQEIEKVSHLISG----REGFDKINKAVQEI---- 491
                            | |.|.|:    |:||...| :||:..    ..|...||:.:||.
  Rat   417 ----------------C-WKKNVRFRGLHRIQTFLK-THLLLAIPHFGAGMLHINRLLQEFRSVS 463

  Fly   492 ---KEETESLLRTNFEIWSGQCSTAVKSGELRLRDDQAVVKFEKEGRQLMRVTFNPKLVTFCQDV 553
               ||..:|.:                     |||.:..:  .||..:.:||..:  .:..|..:
  Rat   464 WLPKEPDKSYV---------------------LRDLKKAI--AKENHRALRVLCH--FLNLCASI 503

  Fly   554 REF---------ENLGYNVPLELRAAATHAAKY----MC--YARRLQQIATFHNTIG------DR 597
            .:.         :.|...|....|...:..:.|    :|  ..::|:|..|:.:.:|      |.
  Rat   504 LQLIHEDTYQMQQGLQERVQNWNRIRKSQGSIYLQRTLCRHLEKKLKQAETWLSKLGMFARLIDY 568

  Fly   598 MIPCQRPI---------MLKNALELQR----LVQSETVAWQDE---SSVQRYVDILQAAVSKLSS 646
            || ||..:         .:.|.|:..|    ||..  :.:.|.   |.:.|...|:|:.:..|.|
  Rat   569 MI-CQNLVSILEDEITSFIANNLQAPRQNPFLVSQ--LVFDDNGQLSPMPRVESIIQSLIKSLQS 630

  Fly   647 DNTLLVGYHEQAKRSVLKLM-STDLFTQNQ-IWKDELRHLRELVATLERQGYTHLDAFKLH---- 705
                       .|.|.||:| ||||.|..: ::.::.:         ::...|.....|.|
  Rat   631 -----------IKTSALKVMQSTDLRTSREPLYSEDNK---------DQDSNTEFPMPKFHGKSS 675

  Fly   706 ----------------W-DHQLYKVLE--------------YQYILGLLDMNNKLPDIHVKLVLR 739
                            | .|.:..|||              |.::...||.|..:
  Rat   676 DAVRLFCGPNVGYVWPWKSHAITNVLEVRGHRLRGQYLHPNYDHVQEDLDKNAGI---------- 730

  Fly   740 QRELVFSPPEEEIRELYFSQLRRFIERPCNFHGLSEHSQELFKSMVTVNRHHFGPLYQRAAELFD 804
            |:.|.       :::.....:|:.::..||.....|...|..|:..:                 .
  Rat   731 QQALA-------VQQALLEDMRQEVQEFCNKQQWVEDIYEFLKAWNS-----------------Q 771

  Fly   805 KLQDFKTIWLPWIALGCVDVDQLCGIHLNEAGDWDRNFRSCKHFSQQLAKLQQAEESIDCIVINV 869
            ||:|.:.                     :...|:.:..|..|::.::::.:     .::.:....
  Rat   772 KLEDLRG---------------------SPISDYVKLVRKLKNWQERVSNM-----PVELLTKTK 810

  Fly   870 LPLRS--DIEYISRRYWESLANSLRTAILTDV-----SLIQEFLQSALQFL---QNVPMDEGSIS 924
            |.|.|  |::    ...||..|:||..||..|     |..|:.::...:||   |.:.:|..:|:
  Rat   811 LLLLSGRDVQ----EELESKLNNLRKNILEQVKNECWSRNQQLMKKLTEFLRVFQTINLDIHAIA 871

  Fly   925 QSGMKYEKIMSKLPQIEKTLEAVRAKDSCLGGWC----KERVTALSGILLQWEQLQ--------- 976
            |...|..:...:...:|:.:|.||:....:...|    .|..|....:|..||..|
  Rat   872 QCSQKLNEANEQYCHLEEQVEYVRSLHDLIRNHCVLFISENETLDIALLDLWEAFQFERSQVSEF 936

  Fly   977 PLLENHAVILQRQVDMIKNQAETQLQNLKNEAEKFLLRWESTISELE-----ANEHSTLDVFKER 1036
            .|.:.||::             .:||.|...|          ::|||     |.....:|..:|:
  Rat   937 LLSKRHAIV-------------PKLQQLMAAA----------LAELEGLLVKALSGPFMDPSQEQ 978

  Fly  1037 RLHWQQLQEKKTQLLEECSKFNMEFPAEMLTPFTEIEEQMEKQSKQWQVYDSFL---TELQP--- 1095
            |...|||...:.|.|...|.||....|                      |.||.   |.:.|
  Rat   979 RSTEQQLGALENQFLNTLSNFNALCYA----------------------YRSFTGHKTTMSPPAS 1021

  Fly  1096 -----VLHEE-WAIYRRRPYVLNEFIGKWEGSVHASIDLPSKRIR-----QQVEQLQSAL----P 1145
                 ||.:. |.:||    :::|...:|:....:..:|...|.:     .:..:|.:||    |
  Rat  1022 GNRPIVLQQRIWRLYR----IIHENFSEWKCVAFSKFNLSMAREKTNAWLTEAARLGTALGQQSP 1082

  Fly  1146 ILQQLQSESLSERHWARIFQLLNHKETKPLHSILLQDI-------------LQDFDVLQ------ 1191
            :||:..  .:.|...|.:..|:.      |.|:.|||:             ||..|:|.
  Rat  1083 VLQRCM--RMLEEFRAYLPLLIK------LGSLELQDVNTQSLLRALGLGGLQSLDLLTLGRLLN 1139

  Fly  1192 ----SAAQEISSIVRQASSEQIVRQALI-ELDQWSVTAQLKLIT---------RTDASGQSVSLI 1242
                ..|..|:. |.|...|:|..|.:: ::.|:....||:|:.         .|....:..:|.
  Rat  1140 CPLLEFADRINQ-VWQRDKERIHAQEILQQMQQYWEGRQLRLLNFILQVPYRPPTSERSKRPALR 1203

  Fly  1243 KDYQEVLNK------IGDNQSLLQSANNS--AAFESFSDQ--------AELWESRLNTLDALLSS 1291
            ....|::.|      :.|..||..:..||  |.|:..:.|        |..|.:.:..|.|||..
  Rat  1204 SPQWELVGKDSGTFLLSDYSSLQDAIQNSLQALFKILAIQKSGQLHKIALEWVTIMYDLGALLEV 1268

  Fly  1292 LNHSQRRWVYLEPVFGSGTLQHE----------QALFKRIDKDFRFVMREIEMDPRVTSLTKIN- 1345
            ....|::|::|..|.      ||          .|.||.:|..:|.:||....||.|.||...|
  Rat  1269 WVSFQQKWIFLNKVL------HEMEIEFPAAELNARFKVMDDQYRTLMRISVADPMVLSLIVPNT 1327

  Fly  1346 ---------NITTIVNALETQLARCQQNLMSYITDKRNSFPRFYFLGDDDLLELLGQASKDAEVI 1401
                     ::..::.....:|......|...:...|.:|||.:||.|.:|:.||. :..|....
  Rat  1328 KRSPYFQGQHLQHLLKVGSVELEAIIMGLEDVLYGVRANFPRLFFLSDSELVALLA-SPLDTSEA 1391

  Fly  1402 QRHIRKLFPGCHSLSIRQVGPNPATSSDVNQYSITSVHS-----AEGDELKLSQPVEMKGDIERW 1461
            :...::.||...:::.|....|...:...::.||.:|.:     |.|:|:||.:|:.:..|:.:|
  Rat  1392 KPWAQRCFPYIKAVNFRSKSTNKENNDKDSKSSIETVETISVLGACGEEVKLQEPLPLYPDLPKW 1456

  Fly  1462 LNQLVTVVQDTLRDQIYECYTGTTGGSDNLDEKI---------------------LKKYASQVLA 1505
            |..|.|.::..:.:.:..|.........:|.:.:                     ::.:..|.:.
  Rat  1457 LASLETCLRLVVVNLLQSCVATRLAQGPSLIKALKAMPQQRQMSTQLYVQHWLDAVQVFPWQCIL 1521

  Fly  1506 TARALHFTRQAEQAI---GSMSLGKLK-QQLKDEITHLAALKNKSENGTLISLK----LRALLLD 1562
            .|..:.:..:.|:|:   .:|.|..:. :.|:..:..:.:.::......|.|::    ..:||:.
  Rat  1522 VAEEIVWRAEMEEALLESKTMRLSSVHVRNLEVLVQFIRSQRSSQGEQPLPSVRQTSLFSSLLVK 1586

  Fly  1563 LVHYSGVTEQLQKHNVVHTSDWHWLCQLRYYLGKK-------------GGTSGEVNANRQVC-VR 1613
            .|.:..:.:.|:|:.|...:|:||:.|::|:||..             ..::.|.:.:...| :.
  Rat  1587 AVTHRDIAQLLEKNQVSDLTDFHWVRQIKYHLGSSHLNLKSPLQCLTTTASTEEPSVSPAACWID 1651

  Fly  1614 MVYAEFEYAYEF----LGQASKLVHTRLTHRCYLILTQAMHMGLGGNPFGPAGTGKTECVKALGA 1674
            ::...|.|.||:    ||....|:|.|......|.|.:..:    |...|..|.||.|.|.:|..
  Rat  1652 VLGRSFLYNYEYMGPKLGPLPSLMHERQVFILLLALNEVAY----GAVLGRDGLGKAETVNSLAW 1712

  Fly  1675 MLGRLVLVFNCDENVDTESMSLILTGLARCGAWGCFDEFNRLQEATLSSISM-------LIQPIQ 1732
            .|||.:::..|...::...:|..|.|..:||||...:..::|....||::..       |..|:.
  Rat  1713 ALGRQLVIMPCLPQIEFRCLSNYLNGALQCGAWLLLENVHQLPSGLLSALGQRLDELHHLYAPLY 1777

  Fly  1733 SALKERANSVQ------IG-----ERQIQLNQHCGIFVTLNPAGAEYGGRQKLPGNIQALFRPIV 1786
            ....:..:::.      :|     :.|:.:....|.|:|.:....:      :|.|:..|.||:.
  Rat  1778 QKASKNISTINPTKHLLLGAGFFEKHQVSVRLGFGCFLTFHSLSPD------VPANLHLLLRPVA 1836

  Fly  1787 MQQPEPGEIARVMLFVEGFTEASAIASRIVELFELSGKMLSA---QRHYDWGLRELKTVLMVCGE 1848
            :..|:...:|.:.|...|..:||.:|:|:.:||.|..:::|.   .|     |..||.||    |
  Rat  1837 LAFPDLQRVAELQLLGAGVRDASRMATRLSKLFSLERELVSGTLPSR-----LPLLKQVL----E 1892

  Fly  1849 GLRDQLTSEDNNQS------SANFEMSVVVRCLRSSTMSKLAPHDVNRFEMLLRNVFPEIGSSPA 1907
            ...:.|.:.:.|:|      :|..|.:::...|.|...:.|....:.:.:.||..:||. .|...
  Rat  1893 NTIETLNASEENKSQQPHNLAAAEEAALLRALLHSPLFTILDGLRLQKLQELLCGIFPN-ASHVL 1956

  Fly  1908 PETQLHQSLSAA----FAQLGLCRSERQIEKALQLHEQLQKRMGVVLVGPPGCGKSTI-ISLLK- 1966
            .|...|:.:.:.    ..||||..:...:....||.|.|.|..|::|:|..|.||||. .||.|
  Rat  1957 AEPVCHRLMKSVVVEELQQLGLFPTLNTLTSLEQLSEALSKASGILLLGTAGSGKSTCWKSLFKI 2021

  Fly  1967 ----QALCGTQLK-------VHTISPKSMSRIQLLGRLDADTRQWQDGVLT---HTA----VAVN 2013
                .|:..|..|       || :.|..::..:.||..:..:  |:.|:.|   |.|    ...:
  Rat  2022 QNRLAAMEHTSTKGFQSVETVH-LYPSVLTSQEYLGWSEGSS--WRYGIFTKLLHAAPYCKTVGS 2083

  Fly  2014 QESSQ----VHSWIVCDGSIDPEWIEALNSVLDDNKLLTLPSGWRIQFGSNVNFIFETDDVRHAS 2074
            :|.|:    :..||:|||:.:..|::::..:|.|...|:||:|.:|.......|:.|..:....|
  Rat  2084 EEKSERFTGIQQWIICDGAPNHAWLDSITCLLADPPQLSLPNGQQIARPLGTFFLIEVAEAAGMS 2148

  Fly  2075 PATISRMGIV-----------------NMSYDYYPADGILKHELSKEPYGDLLQSYVDGNFQYAV 2122
            |..:.|..:|                 ::.::|:     |:.|...: :..|.:..|...|::..
  Rat  2149 PTVLGRCALVWCCGEQTWQSMLSVLITSLPHEYH-----LQQETIVQ-FNHLAEVLVPSVFRFLT 2207

  Fly  2123 NWIESQLLLTH-----LPGI----NRAHLLRSLL-LQLH--------------GTQSL-EEYGAA 2162
            ....|..|..|     .||:    :...:||:|| ..||              ||..: :.:.::
  Rat  2208 RIGASSQLQVHGHQAVCPGVAEVTSLIRILRALLDPHLHLFEEEKPHTKEDFSGTDLVTQNFISS 2272

  Fly  2163 TLRALFGYMPNDRQREF----------------------AQLILKHANLY--------VANPNYA 2197
            ..:|     .:||...:                      |.|..:|..|:        .:.|||.
  Rat  2273 KSKA-----QSDRISVYKKERRHLLAISSFLFAIIWGFGAHLSSRHWPLFDDFMRKAISSLPNYP 2332

  Fly  2198 EL--------THYESSRNSLEQYAVDAIETPEKGS--QLIITSYMKSYLDILETLLKTQGTRLPP 2252
            |.        .|......:|..:....:.|..|.|  ....:|.::..|.:::.||...    .|
  Rat  2333 EPPPSALVFDLHINLEDGTLVPFTGQYLSTHVKRSLGSFQPSSQVEQLLYVVDLLLSNG----QP 2393

  Fly  2253 FMLIGPSGSGKTLLLQRAVLENSGYQLATINCSTQLTPRYILHTLKTHCVTVSGIKGREYRPKQA 2317
            .:|.|...:||:..::..|..|.......||.:........|.:...|..|.:|.....::..:.
  Rat  2394 VLLAGEIATGKSAFVEVLVEPNHPTIHRPINPALNSAHLRNLLSRAVHGQTQAGSFVGPHQDSKG 2458

  Fly  2318 RLVLFMKNLDLCQQDSWGACE-VVELLFQLAQRGGFYAENLEWIGVSGLQ------LCASIGGNT 2375
            .::..|::|.|...|...:|: |:|.|.| |..|..|:.|.  :.:..||      ..|::.|.:
  Rat  2459 SILFLMEDLHLAAFDPEKSCQPVLETLRQ-AMEGTIYSHNT--LELQTLQPTVNFLATATVPGYS 2520

  Fly  2376 GK-IAPRYFAINQFVRVSRPTSQDMLE----IVQRRLE--PLLEEHFRGSENRGRSGVNLQHVSE 2433
            .: :.||.:.:...:.::..|...:|.    .:|..||  |.:|.....:....|:.|   ...|
  Rat  2521 ERPLCPRLYRLFTVLALNSMTQDTLLSRHVPSIQAWLERFPSVEREHTLARALVRASV---EAWE 2582

  Fly  2434 SLMDCFEKLQATFTNVGGRQAHYQFSPKCIMKLLDALVFYPASDFNEALYCELLGM--FRDRLIS 2496
            ::.:||..        .....||:|||..:..:|.:|...|..          :|.  |.|....
  Rat  2583 AVCNCFMP--------SPLHPHYRFSPHSVSHILGSLQLLPTR----------MGSRGFVDSFHH 2629

  Fly  2497 EEHVQQFEGI----------LKQTMRKYYGKEKVFFVPKSPKSRGHLHCLTHDEWMEEVQRQVTI 2551
            :||:::..|:          ::..:|.:..:.:..|..:....|...||:   :.:.||.::| .
  Rat  2630 QEHLRRVSGLRGTRLTIMMSMRVMVRLWLHEAQRTFCDRLDSDRERSHCV---KLLLEVAQRV-F 2690

  Fly  2552 CNTENYSITAPITEELLSHVARITRVLSRTD-AHMLIL--GQSGGRHLDAIF-----TAATFQEA 2608
            |:.......|.:.||......::..|.|..: ||..||  ..||....:..|     |.:...|:
  Rat  2691 CSVPGSESLARVCEEEEVEEEKVPEVESEEEIAHWEILSNSDSGSEEEEDPFGLQATTGSFLSES 2755

  Fly  2609 KVVTLQGGP--SYDLTDFYNDLKVAMQTAALEQQMSYLLIE---QCW----------------LS 2652
            .:..|   |  |.:..:..|..:||.|...:....|.|..|   :.|                |.
  Rat  2756 GLAPL---PIKSVNKENTENVSQVAQQLEDIRNSNSKLQSETHKRKWQRAPQTDLSLPLLLPVLL 2817

  Fly  2653 YVP-----DILKPIEALLEGSEI------LELFGDDLETVASTLKQAAQLEGYQESMGTYF---- 2702
            :.|     |::..:|..| ||..      ||...::||      ||.| ....|..|.:.|
  Rat  2818 FYPQENPSDLVFSLELTL-GSNFESPNLYLERQWENLE------KQLA-ASAVQLKMNSDFAQCH 2874

  Fly  2703 ------------LKRARDY-----------LHIIIVLDPNSAKVQDY---FNNFPALHRQM-DLL 2740
                        |.|.|.:           .:..|:|..|..:.:.:   |.:..|:.:.: |..
  Rat  2875 VMVQHVARLVRVLARPRQHGLLLSEFRGTGRNTAIILASNICQARLFHLPFESEEAVFQCLRDAS 2939

  Fly  2741 YVRGESRETIAIL-PKQ-----FIELLNESIAGGGSGRGKVPTCSHFADISDELPSEE------- 2792
            :..|...:::|:| |.|     |.:||  ::|..||...:. |.:...:|.:.||.|.
  Rat  2940 WHAGVLNQSVALLVPDQVNVATFCQLL--ALATSGSFPDQY-TEADLDNIEEHLPKENLVNKYSI 3001

  Fly  2793 ----TSQRYYQLIRTYFHMYNNAANEIDQR-------LGKLQM---GVDK--------------- 2828
                ...|:||.:.:..||:....::..|:       |..||:   .||:
  Rat  3002 KKDTVLNRFYQQVCSNLHMFFLMEDDQVQKQLPSTLFLSLLQLTIASVDRYEPWDQASLVRVAQF 3066

  Fly  2829 --------------------------------------------------LASAHALVDTLKSNA 2843
                                                              |.:.....|.|....
  Rat  3067 RLENDQSLPLDDGSLKCPDFKILIPNVANIMARIHGSSAYYHQHMCPALPLVTPRTFQDFLDMFL 3131

  Fly  2844 AAQEQALGEKRQLA---NEALEMISFTMRNANEQKSSMLELKQQT----------QKSSEQLKIR 2895
            ..|:|.:.:.|..|   ..||:.:...:...:.|.|.:.:|::|.          |...||.||.
  Rat  3132 QQQQQMVLQMRMRARRIQSALKTLRLLVERHSTQTSMLTDLEKQLKGSYKNVGMYQGQLEQCKIL 3196

  Fly  2896 QKEIQQEL------------------AEVEPILAEASNA----VGQIKSEALSEIRSLRAPPEAV 2938
            .|:...|.                  |:.|..|.:...|    :.|::.....||||.|||||:|
  Rat  3197 YKQKMAECQHLESLIENLTRQHDALKAQQEAFLEQMGKAFVGPLSQLRVADFEEIRSYRAPPESV 3261

  Fly  2939 RDILEGVLRLMGIRDTSWNSMKTFLAKRGVKEDIRSLDPARISPENCEAVERLLLAKGDSYEAKN 3003
            ..:.:.:..|.. .:|.|:|.|..|......:::......::.......:.:.|.|.|.|  ..:
  Rat  3262 VKVTDALCDLFH-HETGWSSAKQLLCTEDFYQELVFFPKEKLMDSELAKLSQALRAPGMS--DAS 3323

  Fly  3004 AKRASAAAAPLAAWVQASVRYSRVIQSIKP-----------LEREQNELQKNLNAAEDEMQE--- 3054
            .:..|..||.||.|::|.:||....:...|           |.|||..|.:....|.|.:|:
  Rat  3324 LRSVSIPAANLAVWLRAVLRYGLAQRRGLPTGLLLRQVDATLAREQARLGQFQFQAHDLLQQTQF 3388

  Fly  3055 LASGLDDVDKRVKQLSAKLQTYTQEAAVLELKLQEASGTLQAAELLVEKLSAEYTTWSLQLTELK 3119
            |...|:|.     |||        ...|:|...|...|......:....|:..: .|:.||.:|:
  Rat  3389 LTKKLEDA-----QLS--------HNHVVETLNQAQCGHFHRWPMKSALLTPMH-MWTTQLQKLQ 3439

  Fly  3120 KAHKTLDAKTLLIAIAINY-------------------CAG----LGLEQRCSSLK----RLAAD 3157
            :..||:....||.:.||.|                   |.|    |..:....:|:    |::.:
  Rat  3440 EQAKTVFGDALLCSAAIVYLGPFPPQRRQELLEKWLSLCQGFEEALDPDDVAQALRQKSVRVSKN 3504

  Fly  3158 FHLPSDFDLRGSLLT------EQQQIIWESQGLARDAQIIESAALLREMLSLPYGACPIPLLLDP 3216
            ..||:....|  :||      ||.|...:.:..|:.|:::  ..|||.  .:.:.:...||||||
  Rat  3505 PLLPTRTPFR--ILTLLSCGSEQHQWDRDLKPQAKSARLL--GLLLRS--HIHFSSSRWPLLLDP 3563

  Fly  3217 TQTAAAWL--------------------MAHLKGSG----------------------------- 3232
            :..|..||                    ..|:....
  Rat  3564 SNQAIIWLNPLPPKQNKWLEQPPKESRAKYHVTNQDSEDETEDELESENNEDEDEVSEQREEHKT 3628

  Fly  3233 -------------------RPCELTTHGNDRLPYQLELAVRFGKTLLVTDCEQLRPPVLQLLQGH 3278
                               ...|.|:.|:...|......:....|:|.....:|.|.:|:.....
  Rat  3629 EENESEEENKQEEQETEKENEAESTSSGSSSSPPSETQCLPSYLTVLSGTDPELGPQLLEAAANG 3693

  Fly  3279 VFVRFNKRQLAIGSKLVDLHESFQLVLISKS--------------------HRLD--LPEEQRSQ 3321
            :.|.....:|::|.      :..|.:|..|:                    |.||  |..|....
  Rat  3694 LPVLLTNMELSLGC------QELQWLLSKKNLIPPYVQPGFCLFLSTTFPIHALDRVLGYELLKG 3752

  Fly  3322 LNVLKFTVTAAGLADQLMSKAIVLKNGELE----------QQRIELLQKEGHLLKQRMEMQDKLL 3376
            ||||...:....|.:|::.:.:..:..|||          .:..|.::.:...|...:..|:|:.
  Rat  3753 LNVLDLGLNMEILEEQMLHEILCRERPELETRWQDLKVRAAENYEAMKADEEQLLVILLRQNKMR 3817

  Fly  3377 EQLSKSEGDILKNEQLLESLNEIKQGSTQIDEALKQSGQIRDTLLAQFGSLRELSSRAATFYAGL 3441
            ::.|:...::::.:..:..||  .||. ::||...:       :.|.:...|:::      |.|:
  Rat  3818 QKPSRFLREMVRTQAKICQLN--AQGE-ELDEQKLE-------VAALWAPYRQVA------YHGM 3866

  Fly  3442 IQGYELSPLVYIELFLGALSKS-----QRDESKVYDC------------------LVRSVYMN-- 3481
            .....||.|..:..|....|::     :|....:..|                  |.|.:.:|
  Rat  3867 AMVEALSSLQNLLPFFCMKSENWLAVIRRAIDSMKSCDSYHGEDLPSHLLRMKIHLARQLLINTV 3931

  Fly  3482 ------------------LARATSRDSQLS-LSLWVCHQAYPDR--------------LNPKEWE 3513
                              :.:.|.:..:|. |:||....|.|..              |:.:.||
  Rat  3932 VALGLIQTPLVGAFGALAMLQVTKKTPKLERLALWPGLLASPSSGHNIQIPGVTRPAWLSSRAWE 3996

  Fly  3514 LFVNNFMGSSDGSMVLSQLGKLPDCMPKEAQLKLAMLLQLFPDLRSKLQLEKDYIWRGFIEAQAD 3578
                                   :|...|       ||..|..||:.|....| :|:.::...:.
  Rat  3997 -----------------------ECGALE-------LLSPFAGLRASLASHSD-VWQDYLSLSST 4030

  Fly  3579 DVLPALG------SSFQRVLIAQIFRPDLMLHQLRKVSSDLLG--ISPDASTQPSVEQLLQQSSC 3635
            .:.||.|      |.||::::.::.|||.::..|..:::.|||  :..|......:...:|.:
  Rat  4031 VLGPAPGPNSEPLSLFQKLILWRVLRPDCLVGALADLTTSLLGRPLDEDLDAPTMIFDHIQPT-- 4093

  Fly  3636 DRPILMVSHAENDPT------TELRKWA---NQKYREMAIGKGVE-----KRVLSEMRQAAIDGH 3686
             :|||::......||      |.:||.|   ..:.|...|..|.|     ..|::.:.||.:.||
  Rat  4094 -QPILILLPPPGHPTATLHPVTVIRKLAASEKPQKRLHVIALGSEDWDPVSTVVNTLSQAMLQGH 4157

  Fly  3687 WLCVKNVHLVP-----------------------EFLTQME-RELSEIQKSKDFRLWLLC--EST 3725
            ||.:.|.||:|                       |.:.:.| |.::.:.  :||||||:.  |::
  Rat  4158 WLVLDNCHLMPFWPRELLQPLQGLLDGAKVVSDSELIAEPESRTVATVH--RDFRLWLIASTEAS 4220

  Fly  3726 EGFSEAAIYKCLKVRYEQPKGLKQIVMRLLQNFAAEQDQKLKNQPKSLKMRLVYFVLTAVLQQRR 3790
            ...........:.|.:.|...|.:|::.     :.:..|:|..|  |.......|.|..:|..|:
  Rat  4221 TSLPGVLTQHSMPVFWNQSLELGRILID-----SVDSQQELSTQ--SFTQTFPLFFLYGLLVHRQ 4278

  Fly  3791 QF-----IPQG-WSKYYEFGEADLKAALGILRMMDQQLNSGKCDWLLMQRLSEALAYGGRVNNQR 3849
            .:     ..:| ||      :..|...|.|...:...|::.....|   .|:.::.|||.:.:..
  Rat  4279 LYGLKLQAHRGRWS------QVTLTRVLQIQEQLWASLSNPSAALL---ELAASVLYGGPLRDLE 4334

  Fly  3850 DLEILTTYLNQFCSADVLSNRWSP------LGLSLSIPTSGQLQ---DYYAALEKLPDTDEPSMY 3905
            |.|.|.: |...|......|...|      |...:..|..|:|.   |..|.:..||...||...
  Rat  4335 DRETLVS-LTGACLNPRNMNWVQPHTPQYLLATLMPSPELGELDARTDCKAQMHLLPTPSEPRTC 4398

  Fly  3906 GLANQAQQQREIEQAKRVIKELRGLHYGRGLAKDSGGAGESKGNDQLTGRQKLEQQIKPLLNLWR 3970
            ||....|......|::.::..||... ...:....||..:.|   :...||:|.|..|.|:.|..
  Rat  4399 GLNEGPQAWLLRRQSRALLSALRQCS-STWVPTVCGGIVQRK---ERRLRQRLVQAKKRLVALQA 4459

  Fly  3971 KLAASCTIIQTMKEAKTDVGESPWAL-----------FVLAELKLGADLYGIVHQTLSQMHAWLK 4024
            .|        |....::....:|||:           |:..|:.....|.|::.:.|..:...||
  Rat  4460 LL--------TNNRYRSGQCVTPWAVLGPNARPPLEGFLETEVLELKQLVGMLLRDLDCLLQQLK 4516

  Fly  4025 ESQEVDGSTLRTLAEQ----QIPASWLKLWP-GP 4053
            .......|....:|:.    ::|..|....| ||
  Rat  4517 GKTPCTSSRCAEVAQALWAGRLPQPWRSHAPAGP 4550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btv	NP_001036369.3	DHC_N1	200..618	CDD:285571	97/487 (20%)
		DHC_N2	1072..1481	CDD:285579	111/503 (22%)
		P-loop_NTPase	1621..1847	CDD:304359	62/250 (25%)
		P-loop_NTPase	1919..>1967	CDD:304359	20/57 (35%)
		P-loop_NTPase	1947..2081	CDD:304359	43/157 (27%)
		P-loop_NTPase	2565..>2733	CDD:304359	48/237 (20%)
		MT	2821..3138	CDD:289543	88/433 (20%)
		AAA_9	3179..3401	CDD:289547	51/321 (16%)
		Dynein_heavy	3536..>4051	CDD:281078	132/592 (22%)
Dnhd1	XP_008758037.1	DHC_N2	1026..1476	CDD:285579	106/469 (23%)
		P-loop_NTPase	1659..1877	CDD:304359	55/227 (24%)
		P-loop_NTPase	2374..2660	CDD:304359	63/313 (20%)
		P-loop_NTPase	2877..3126	CDD:304359	37/251 (15%)
		MT	<3198..3475	CDD:289543	67/293 (23%)
		AAA_9	<3672..3810	CDD:289547	27/143 (19%)
		Dynein_heavy	3987..4746	CDD:281078	138/629 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900