DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btv and Dhc62B

DIOPT Version :9

Sequence 1:	NP_001036369.3	Gene:	btv / 35073	FlyBaseID:	FBgn0023096	Length:	4236	Species:	Drosophila melanogaster
Sequence 2:	NP_995958.2	Gene:	Dhc62B / 38226	FlyBaseID:	FBgn0013811	Length:	3964	Species:	Drosophila melanogaster

Alignment Length:	4248	Identity:	912/4248 - (21%)
Similarity:	1656/4248 - (38%)	Gaps:	973/4248 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 YVKHPWLGDSHVPKRGQQFKERLSEI--RSIKQLYKQIATLLEDTELQEMFQEQAPFTEFNIFDT 350
            |:|:|.|            |.|:||:  |...|..||.|.   |.:::...|:..|..:..:...
  Fly    24 YMKNPLL------------KFRISEVHERRHYQFLKQKAA---DVKVRVARQQWQPEPDMRLLPQ 73

  Fly   351 SSLGQNKWHKALQHFEQ---------VLQPIDERIAAALKRQLHNHLSNPRQVIFIFSKYETLIQ 406
            |            |:|.         |:.|:..|..|.:.......|.|         ||..|:|
  Fly    74 S------------HYEDNLRREVRKIVVPPMLRRTEAKILSFASERLKN---------KYPELVQ 117

  Fly   407 R-------------------------------PAVLEL------------------LTIEREQFL 422
            .                               ||..||                  ....|.:..
  Fly   118 AYMHDVHEEFNRLMKVYSMKNILRHPEFSDEDPAQFELPRPDIGFRRPGRTQNYSNFLENRRRIA 182

  Fly   423 QSLHILLQDLRKAMVDSNMEPDTGHLSVICNECRWLKVVQHQIQEIEKVSHLISGREG------- 480
            |.|.||...|| |:::.:: .:...|:.|.|.......:|.|:.        :.|||.
  Fly   183 QKLLILQLPLR-AILNISV-GELPKLACIFNYVLATGAMQQQLG--------LGGREALSYKFYH 237

  Fly   481 ------FDKIN---------KAVQEIKEETESLLRTN---FEIW--SGQCSTAVKSGELRLRDDQ 525
                  .||:|         |.||.:::    |:|..   ...|  |.....|:.:.|:   .:.
  Fly   238 KYIQNQLDKVNTFLRWTWYPKIVQVLRK----LMRKRVMPMSTWKRSWNAMEALMNREM---TNM 295

  Fly   526 AVVKFEKEGRQLMRVTFNPKLVTFCQDVREFENLGYNVPLELRAAATHAAKYMCYARRLQQIATF 590
            .:..||    ::.|:..:|:.:...:...|:..  ::..|:.|..|      ....|...:|||.
  Fly   296 KIRTFE----EMYRMCSHPRTMPMMRMSLEWSE--FSSDLDTRPNA------WSILRTFAEIATE 348

  Fly   591 HNTIGDRMIPCQRPIMLKNALELQRLVQSETVAWQDESSVQRYVDILQAAVSKLSSDNTLLVGYH 655
            .:.:|.||.|            ||..||:.|               ..||.:|::
  Fly   349 ISMVGYRMEP------------LQPQVQTLT---------------SMAAYAKVN---------- 376

  Fly   656 EQAKRSVLKLMSTDLFTQNQIWKDE---LRHLRELVATLE--RQGYTHL------DAF-----KL 704
                 ..||:...|.|.::.|.|.:   ||..:|::..:|  |..|..|      ||.     :.
  Fly   377 -----DYLKIEMNDNFLKDVIDKVQNIILRTYQEVIQYVEGFRDKYYALYSWQERDALNQFLSEP 436

  Fly   705 HWDHQLYKVLEYQYILGLLDMNNKLP--DIHVKLVLRQRELVF---SPPEEEIRELYFSQLRRFI 764
            |...:.:..::..|  |.:.|....|  :..|..|:.....:|   :..|..|.|:....:|..|
  Fly   437 HEFEEYFARIDMYY--GFIQMLRSEPATEYFVMAVIHNEPAIFGLRTLAENLIHEITTIIIREHI 499

  Fly   765 ERP---CN-FHGLSEHSQELFKS----------MVTVNRHHFGPLYQRAAELFDKLQDFKTIWLP 815
            :..   |: |..:...:.|:.||          |:.|.:       .:.|||.|::|
  Fly   500 KAEVDICDEFEKIKYRALEIPKSTEELLESAEYMIHVKK-------DKIAELTDRIQ-------- 549

  Fly   816 WIALGCVDVDQLCGIHLNEAGDWDRNFRSCKHFSQQLAKLQQAEESIDCIVINVLPLRSDIEYIS 880
                .|:.|    |.::.|..:..:     .||...:..:...::..|....|.    |..|...
  Fly   550 ----YCLQV----GTNIVELTEMSK-----YHFDLTIKTINWIKDINDICDYNA----SQQEQFK 597

  Fly   881 RRYWESLANSLRTAILTDVSLIQEFLQSALQFLQNVPMDEGSISQSGMKYEKIMSKLPQIEKTLE 945
            ..:                   :|.||..::.| |..:||            ::.||..|:....
  Fly   598 FTF-------------------EEHLQEVIKKL-NSDIDE------------LLPKLTVIDDMSR 630

  Fly   946 AVRAKDSCLGGWCKERVTALSGILLQWEQLQPLLENHAVILQRQVDMIKNQAETQLQNLKNEAEK 1010
            ..:.:||                              .:|||..:|.:|...:
  Fly   631 PDKFRDS------------------------------YIILQNFIDQLKTFDD------------ 653

  Fly  1011 FLLRW---ESTISELEANEHSTLDVFKERRLHWQQLQEKKTQLLEECSKFNMEFPAEMLTP-FTE 1071
             .:.|   |..:.::...|:..||:.|.....:.:|.:...:.....|.:| :.|.|.|.| |.|
  Fly   654 -YVAWINKEEKLFKVALTEYPKLDIIKTFVYPFAELMKCCIEWQRYLSVWN-DGPFEYLEPQFVE 716

  Fly  1072 IEEQMEKQSKQWQVYDSFLTELQPVLHEEWAIYR---RRPYVLN---EFIGKWEGSVHASIDLPS 1130
                        :..|.:|.|.|    :....||   ::..:.|   :|.|:.|....|...:|.
  Fly   717 ------------RTTDDYLKEFQ----KNQKYYRVKIKQDLIDNPVCKFKGQTEDPDPAKHPVPL 765

  Fly  1131 K---RIRQQVEQLQSALPILQQLQSESLSERHWARIFQLLNHKET----KPLHSIL---LQDILQ 1185
            :   .:.|.::...:.:.|:..:.:.:|.:|||..:.::.....|    ..|..||   |..||.
  Fly   766 RLCTSMIQSIKDFTTGVFIVNTMCNPALRKRHWKEMSEIAGFDVTPDAGTTLRKILNSGLDPILD 830

  Fly  1186 DFDVLQSAAQEISSIVRQASSEQIVRQALIELDQWSVTAQLKLITRTDASGQSVSLIKDYQ---- 1246
            .|:::...|.:                   ||..|:...               ::||:::
  Fly   831 QFEIISIGANK-------------------ELQLWNALQ---------------AMIKEWETRVF 861

  Fly  1247 ----------EVLNKIGDNQSLLQS-------ANNSAAFESFSDQAELWESRLNTLDALLSSLNH 1294
                      ::|:.:.|.|:||..       ...||..:...::...|..::..::..|.....
  Fly   862 PYGPYKETGVQILSSLDDIQALLDDHILKTLVMRGSAFMKPCEEEVRAWYEKIMRVNETLDQWGK 926

  Fly  1295 SQRRWVYLEPVFGS----GTLQHEQALFKRIDKDFRFVMREIEMDPRVTSLTKINNITTIVNALE 1355
            .|..::||.|:|.|    ..:..|..||..:::.:...|..:...|.|.....::.:...:....
  Fly   927 VQANYLYLLPIFSSKDIVAQMPEEGRLFVIVEQTYTRNMGLVLRQPLVMETAPVSGLLESLQKAN 991

  Fly  1356 TQLARCQQNLMSYITDKRNSFPRFYFLGDDDLLELLGQASKDAEVIQRHIRKLFPGCHSLS---- 1416
            ..|......:.:|:..||..||||:||.:|::||:|.: :||...:..|:.|.|.|.:||.
  Fly   992 ELLEDIATGVSNYLEKKRLYFPRFFFLANDEMLEILSE-TKDPLRVLPHLSKCFEGINSLEFDAA 1055

  Fly  1417 ---IRQVGPNPATSSDVNQYSITSVHSAEGDELKLSQPVEMKGDIERWLNQLVTVVQDTLRDQIY 1478
               :..:..:..|...:.|.|.    :|.|            |.:|:|   |:.|..:.|:...|
  Fly  1056 KNVLAMISSDKETIEFIEQVST----AAAG------------GSVEKW---LIGVEDEMLKAVRY 1101

  Fly  1479 ECYTGTTGGSDNLD----------EKILKKYASQVLATARALHFTRQAEQAI-----GSMS-LGK 1527
            :         :.|.          |.:|:.....|||.:: :::..:....:     |:|: :..
  Fly  1102 Q---------NELSFAHYPKVKRHEWVLEWPQMTVLAISQ-VYWASRVHGCLRRTFGGNMTIMMN 1156

  Fly  1528 LKQQLKDEITHLAALKNKSENGTLISLKLRALLLDLVHYSGVTEQLQKHNVVHTSDWHWLCQLRY 1592
            ..|:|..|:..:..|....:...|..:.:::|::..||...|:|.|.|:.|....|:.||.|:||
  Fly  1157 FFQELSKELNDIVTLVRSPKISNLNRITIKSLIVIDVHAKDVSEDLIKNKVSSEFDFQWLAQMRY 1221

  Fly  1593 YLGKKGGTSGEVNANRQVCVRMVYAEFEYAYEFLGQASKLVHTRLTHRCYLILTQAMHMGLGGNP 1657
            |.           .:.:..||::.|...:|.|:||.:.:||.|.||.|||..|..|..:.|.|.|
  Fly  1222 YW-----------EDDKTWVRIINATVPFANEYLGNSDRLVITPLTDRCYRTLVGAYQLHLNGAP 1275

  Fly  1658 FGPAGTGKTECVKALGAMLGRLVLVFNCDENVDTESMSLILTGLARCGAWGCFDEFNRLQEATLS 1722
            .|||||||||..|.|...|.....||||.:.:|.::|.....|||.||||.|||||||::...||
  Fly  1276 EGPAGTGKTETTKDLAKALAVQCKVFNCSDGLDYKAMGKFFKGLASCGAWACFDEFNRIELEVLS 1340

  Fly  1723 SISMLIQPIQSALKERANSVQIGERQIQLNQHCGIFVTLNPAGAEYGGRQKLPGNIQALFRPIVM 1787
            .::..|..|..|::..|........::.||..|.:.:|:||.   |.||.:||.|::.|||.:.|
  Fly  1341 VVAQQILLIIQAVRSNATKFMFEGTELTLNPACYVCITMNPG---YAGRSELPDNLKVLFRSVAM 1402

  Fly  1788 QQPEPGEIARVMLFVEGFTEASAIASRIVELFELSGKMLSAQRHYDWGLRELKTVLMVCGEGLRD 1852
            ..|:...|..:.|:..||.:|..:|.:||..:.|..:.||:|.|||:|:|.:||||..|| .::.
  Fly  1403 MVPDYAMIGEISLYSYGFVDARKLAVKIVTTYRLCSEQLSSQNHYDYGMRAVKTVLSACG-NIKK 1466

  Fly  1853 QLTSEDNNQSSANFEMSVVVRCLRSSTMSKLAPHDVNRFEMLLRNVFPEIGSSPAPETQLHQSLS 1917
            |...|        .|..:::|.|....:.|....||..||.::.::||.| ..|..:..|.:|
  Fly  1467 QYPDE--------VEDILLLRSLIDVNLPKFLSFDVPLFEGIISDIFPGI-KLPHIDYSLVES-- 1520

  Fly  1918 AAFAQLGLCRSERQIE-------KALQLHEQLQKRMGVVLVGPPGCGKSTIISLLKQALCGTQLK 1975
             .|.::.|   |..:|       |.:|.:|.:..|.|.:|||.|..|||..:.:|.:.|...::|
  Fly  1521 -EFKRVCL---EEVLEPAPSFLLKVIQTYEMIIVRHGFMLVGEPLAGKSKTLQVLAKVLSALKIK 1581

  Fly  1976 V--------HT----ISPKSMSRIQLLGRLDADTRQWQDGVLTHTAVAVNQESSQVHSWIVCDGS 2028
            .        |.    ::|||::..||.|..|..:.:|.||::...........:....|::.||.
  Fly  1582 APQKSNYFQHVQMGIMNPKSITMNQLYGSFDPISYEWTDGLVAKIFRDFAMTPTPDRKWVIFDGP 1646

  Fly  2029 IDPEWIEALNSVLDDNKLLTLPSGWRIQFGSNVNFIFETDDVRHASPATISRMGIVNMSYDYYPA 2093
            :|..|||.:|:||||||.|.|.||..|...:.::.:||..|:..|||||:||.|::.|.......
  Fly  1647 VDAVWIENMNTVLDDNKKLCLTSGEVITMSNEMSMVFEVMDLAQASPATVSRCGMIYMEPSTLGW 1711

  Fly  2094 DGILKHELSKE----------PYGDLLQSYVDGNFQYAVNWIESQLLLTHLPGINRAHLLRSLLL 2148
            ....|..|.|.          ||...|..::....|..|....||.:   .||.....|....|.
  Fly  1712 RAFAKSWLKKADPRWADEEGVPYVMALMQWLLPPCQTFVRRFCSQFI---KPGEFNCMLTTFDLF 1773

  Fly  2149 QLHGTQSLEE------------YGAATLRALF---GYMPNDRQREFAQLILKHANLYVANPNYAE 2198
            .:...:::||            :.||.|.||.   |.:.:...||...:.||  .|:..:|...|
  Fly  1774 DMQIAEAIEENPEDYQKYLQTYFQAAILFALIWGVGGVLDTASREKFDVFLK--KLWDTDPPPPE 1836

  Fly  2199 LTHYESSRNSLEQYAVDAIETPEKGSQLIITSYMKSY---------------LDILET------- 2241
                  ....:|      |..|.:|   ::..|:..|               :|:.||
  Fly  1837 ------PLGKME------ITPPTEG---LLVDYVFLYKQRGAWRYWPDLAKRMDVEETKTGVIVP 1886

  Fly  2242 ---------LLKTQGTRLPPFMLIGPSGSGKTLLLQRAVLE-------NSGYQLATINCSTQLTP 2290
                     |||.........:|:||:|:|||:.:|..::.       .:|:...|:..|.....
  Fly  1887 TVDTARYIHLLKMHVEHKKRMLLVGPTGTGKTVYVQNYLMNKLDKEVFETGFITFTVMISANQCQ 1951

  Fly  2291 RYILHTLKTHCVTVSGIKGREYRPKQARLVLFMKNLDLCQQDSWGACEVVELLFQLAQRGGFY-- 2353
            ..::..|:.   ...||.|   .||..:.|||:.::::..::.:||...:|||.|....|..|
  Fly  1952 DLLISKLQK---WKRGIYG---PPKGMQSVLFVDDMNMPVKEVYGAQPPLELLRQFFDYGHVYDL 2010

  Fly  2354 --AENLEWIGVSGLQLCASIGGNTGKIAPRY------FAINQFVRVSRPTSQDMLEIVQRRLEPL 2410
              :..:....|..:..|...||:...:..|:      ::||.|      :...|..|.   |...
  Fly  2011 KDSSKVYIHNVLIMAACGLPGGSRQDVYARFLNHFNVYSINTF------SDDSMFRIF---LNVA 2066

  Fly  2411 LEEHFRGSENRGRSGVNLQHVSESLMDCFEKLQATFTNVGGRQAHYQFSPKCIMKLLDALVFY-- 2473
            |....|....:....|..|.|| :....::.:|:.......: :||.|:.:.|.:::......
  Fly  2067 LNGFRRAGHGQDVFVVTNQIVS-ATQSIYKSVQSEIRATPSK-SHYIFNLRDISRVVTGCTLVRK 2129

  Fly  2474 -PASD---FNEALYCELLGMFRDRLISEEHVQ------------QFEGILKQTMRKY--YGKEKV 2520
             ..||   |....|.|.:.:|.|||:.:...:            .|:..::....:|  .|.::.
  Fly  2130 ESVSDKKIFVRVWYHEAMRVFYDRLVDDVDRKWMFDKLNECLKANFKDKVETVFERYCVQGPDEA 2194

  Fly  2521 FFVPKSPKSRGHLHCLTHDE--------WME----EVQRQVTICNTENYSITAPITEEL------ 2567
            .|..::  :...|..:..||        :.|    ||...:.:.:.::|:.|.....::
  Fly  2195 VFTMEA--ASNILFGVYFDEDSVPDERRYEEVPSVEVFLNLALTSLDDYNSTRRNKMDITLFTFA 2257

  Fly  2568 LSHVARITRVLSRTDAHMLI--LGQSGGRHLDAIFT---AATFQEAKVVTLQGGPSYDLTDFYND 2627
            |.|:.||.|::|...|..||  ||.||.:.|..:.|   ..:|.:.::.     .:|...|:::|
  Fly  2258 LQHLNRICRIISIQGASALIIGLGGSGRQSLTKLATNMVQTSFFQPEIT-----KNYGANDWHDD 2317

  Fly  2628 LKVAMQTA-ALEQQMSYLLIE-QCWLSYVPDILKPIEALLEGSEILELFG-DDLETVASTLKQAA 2689
            :|..::.| .:.:..::|:.| |..:..   .|:.|:.||...|:..:|. |:.:.|...::.||
  Fly  2318 IKAILKEAGGMNKHTTFLITENQIKMEL---FLQDIDCLLNQGEVPNIFPIDEKQEVLEMVRLAA 2379

  Fly  2690 Q-----LEGYQESMGTYFLKRARDYLHIIIVLDPNSAKVQDYFNNFPALHRQMDLLYVRGESRET 2749
            |     ::.....:.::|:.|.:..||:|:...|....::.....:|:|.....:.:......|.
  Fly  2380 QGGNRNIDVSALQVFSFFVDRCKQKLHMILSFSPIGDALRTRVRLYPSLVNCCTIDWYDSWPEEA 2444

  Fly  2750 IAILPKQFIELLNESIAGGGSGRGKVPTCSHF---ADISDELPSEETSQRYYQLIRTYFHMYNNA 2811
            :.::.|  :.|::.::.........:.||.:|   |..|.....:.|.:..||...::..:..:.
  Fly  2445 LQMIAK--MSLVDVNVPSEDIKLAIMDTCQYFHTTAARSTRAFCQMTGRHIYQTNASFIELIRSF 2507

  Fly  2812 ANEIDQR-----LGKLQM--GVDKLASAHALVDTLKSNAAAQEQALGEKRQLANEALEMISFTMR 2869
            ...|:::     |.|::.  |:|.||.|.|.:..::.:..|.:..|                 :.
  Fly  2508 QTLIERKQSETMLAKMRYIGGLDTLAQAAAAISIMQRDLNALQPKL-----------------VA 2555

  Fly  2870 NANEQKSSMLELKQQTQKSS---EQLK--------------IRQKEIQQELAEVEPILAEASNAV 2917
            .|...:..|||:.::|..:|   ||:|              :.:::.:::||:..|:|.:|..|:
  Fly  2556 LAESSRKMMLEINKETLAASAAAEQVKRDEEVASVQAEAAQVLKQDCERDLAKAIPVLEDALAAL 2620

  Fly  2918 GQIKSEALSEIRSLRAPPEAVRDILEGVLRLMGIR-------------DTSWNSMKTFLAKRGVK 2969
            ..:|...::.::|::.||..::.::..|..:.||.             ...|...|..|.:....
  Fly  2621 NTLKPADITLVKSMKNPPPVIKLVMAAVCVIKGIPPERIPDPASGKMVQDYWGPSKRLLGEMNFL 2685

  Fly  2970 EDIRSLDPARISPENCEAVERLLLAKGDSYEAKNAKRASAAAAPLAAWVQASVRYSRVIQSIKPL 3034
            ..::..|...|..|..:.:.:..:...| ::.|...:||:||..|..|:.|.:.|..|.:.:.|.
  Fly  2686 PGLKEFDKDNIPTEIVKRIHKEFIPNKD-FDPKVVAKASSAAKGLCQWIIAMMMYDEVAKVVAPK 2749

  Fly  3035 EREQNELQKNLNAAEDEMQELASGLDDVDKRVKQLSAKLQTYTQEAAVLELKLQEASGTLQ---- 3095
            :.:....:|..   .|.|:.||      .||...|:.:     ::.|:|.::|.:|:..:|
  Fly  2750 KAKLAGAEKEY---ADTMEFLA------QKRALALALE-----EKVALLNIELDKANAEMQKTEE 2800

  Fly  3096 ----------AAELLVEKLSAEYTTWSLQLTELKKAHKTLDAKTLLIAIAINYCAGLGLEQRCSS 3150
                      .||.|:..|..|.:.|:....:|::.:..|....|:....|.|.:.:.|:.|...
  Fly  2801 HAESCRNKLLRAEALIGGLGGEKSRWNKAAEDLQELYDHLPGDVLISCGIIAYLSAVNLQYRSEC 2865

  Fly  3151 LK---RLAADFHLP-----SDFDLRGSLLTEQQQIIWESQGLARDAQIIESAALLREMLSLPYGA 3207
            :|   :...|..:|     |..|:.|..:|.|.   |:..||..|....|:|.:...  |..|.
  Fly  2866 VKDWFKKVTDLKIPCSSHYSITDVLGLEVTIQN---WQLDGLPNDEFSSENAIISAN--SSRYS- 2924

  Fly  3208 CPIPLLLDPTQTAAAWLMAHLKGSGRPCELTTHGNDRLPYQ--LELAVRFGKTLLVTDC-EQLRP 3269
                |.:||...|..|    ||...|...|.....::..|.  :..|:.:|..:::.:. |:|..
  Fly  2925 ----LFIDPQAQANNW----LKNMERKNRLNCVKFNQSNYMKVIAEALEYGTPVIIENVQEELEV 2981

  Fly  3270 PVLQLLQGHVFVRFNKRQLAIGSKLVDLHESFQLVLISKSHRLDLPEEQRSQLNVLKFTVTAAGL 3334
            |:..:|....||:...:.:::|..:|.::.:|:|.:...........|..:::.|:.|.:|...|
  Fly  2982 PLDPILMRQTFVQGGIKHISLGESVVPVNPNFRLYMTCNLRNPHFLPETFNKVTVINFALTQNAL 3046

  Fly  3335 ADQLMSKAIVLKNGELEQQRIELLQKEGHLLKQRMEMQDKLLEQLSKSEGDILKNEQLLESLNEI 3399
            .|||:|..:..:..:|::.||.|..:.........:.::.:|:.|| :.||||:||..::.|.:.
  Fly  3047 MDQLLSIVVAKERPDLQELRITLTTEAAANKGALRDAENMILKTLS-AGGDILENEAAIQILADS 3110

  Fly  3400 KQGSTQI---DEALKQSGQIRDTLLAQFGSLRELSSRAATFYAGLI-----------QGYELSPL 3450
            |..|..|   .||.|::       :|:..:.| |:.:....::.::           ..|:.|..
  Fly  3111 KGLSKDIVEKQEAAKET-------VAKIEAFR-LNYKPVAVHSSILYYSITDLPNIDPMYQFSLN 3167

  Fly  3451 VYIELFLGALSKSQRDESK------VYDCLVRSVYMNLARATSRDSQLSLSLWVCHQAY--PDRL 3507
            .||.|::.::..:.:.:..      :.|...|::|.|:.|:.....:|..|..:..:..  ..::
  Fly  3168 WYINLYMYSIETANKSKDLPRRIKFLVDGFTRNLYNNVCRSIFEKDKLLYSFILTARILLGTGQV 3232

  Fly  3508 NPKEWELFVNNFMGSSDGSMVLSQLGKLPD--CMPKEAQLKLAMLLQLFPDLRSKLQLEKDYI-- 3568
            ..:.:...|.|...|::       :...||  .:.:...|.:..|.:| .:||..:...|.::
  Fly  3233 EMRHFAHLVTNAKESTN-------IPPNPDPTWITETVWLNVLRLEEL-KELRGIVDHFKSHLHA 3289

  Fly  3569 WRGFIEAQADDVLPA------LGSSFQRVLIAQIFRPDLMLHQLRKVSSDLLGISPDASTQPSVE 3627
            |:...:..:.:..|.      ..::|:::::.:..|||.:...:|...::.:|.......:..:.
  Fly  3290 WQAIYDHSSPEKQPLPPPWQDKTTAFEKIIVLKALRPDSVFLAVRLFIAESIGDQYVTPPEFDIS 3354

  Fly  3628 QLLQQSSCDRPILMVSHAENDPTTELRKWA-----NQKYREMAIGKGVEKRVLSEMRQAAIDGHW 3687
            :....|:...|::.:.....||...|..:|     .:.::.:::|:|......:.::.|...|:|
  Fly  3355 KSYADSTALTPLVFILSPGADPLGSLLAFAEKMGQEETFQSISLGQGQGPIATALIKNAQEMGYW 3419

  Fly  3688 LCVKNVHLVPEFLTQME---RELSEIQKSKDFRLWLLCESTEGFSEAAIYKCLKVRYEQPKGLKQ 3749
            :|::|.||...::..:|   ..:.....:.:||:||....|..|....:...:|:..|.|.|||:
  Fly  3420 VCLQNCHLAASWMPYLEYLWENMDTFNTTPNFRIWLTAYPTPQFPVTILQNGVKMTNEPPTGLKE 3484

  Fly  3750 IVMRLLQN----------FAAEQDQKLKNQPKSLKMRLVYFV--LTAVLQQRRQFIPQGWSKYYE 3802
            .:||...:          ..|:||:..        .||:|.:  ..||:|:||::.|.||:..|.
  Fly  3485 NLMRSYNSEPINDYEFYTGCAKQDRAF--------TRLLYGICFFHAVVQERRKYGPLGWNIAYG 3541

  Fly  3803 FGEADLKAALGILRMMDQQLNSGKCDWLLMQRLSEALAYGGRVNNQRDLEILTTYLNQFCSAD-V 3866
            |.|:||:.::..|.|:..|.:....|  .:..|:....|||||.:..|..::.|.|..||:|. |
  Fly  3542 FNESDLQISVLQLSMLLNQYDHVPYD--AISYLTSECNYGGRVTDNWDRRLIVTILADFCNAQAV 3604

  Fly  3867 LSNRWSPLGLSLSI-PTSGQLQDYYAAL-EKLPDTDEPSMYGLANQAQQQREIEQAKRVIKE--- 3926
            ..||:........| |...:.::....| |.||....|.:|||...:...|:::..|.::..
  Fly  3605 TDNRYRFASDDRYILPRKTEHREILRYLDENLPSLAPPEVYGLHANSGITRDLQTTKTLLDSMIL 3669

  Fly  3927 LRGLHYGRGLAKDSGGAGESKGNDQLTGRQKLEQQIKPLLNLWRKLAASCTIIQTMKEAKTDVGE 3991
            |.|..     |..|.|||.|           :||.|..            ||.|..:|...|:
  Fly  3670 LLGSE-----AAGSAGAGVS-----------VEQVILD------------TIKQIEREMPADM-- 3704

  Fly  3992 SPWALFVLAELKLGADLYGIVHQ------TLSQMHAWLKESQEVDGSTLRTLAE----------- 4039
                     :::..|:.|.:.:.      .:.:|..:||..:|: .:|.|.||.
  Fly  3705 ---------DIEAAAEKYPVDYNESMNTVVVQEMERFLKLQKEI-RTTCRDLAMGIKGIIVMTPD 3759

  Fly  4040 ----------QQIPASWL-KLWP 4051
                      .:||..|: |.:|
  Fly  3760 LENVMTAMKFNRIPTKWMSKSYP 3782

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btv	NP_001036369.3	DHC_N1	200..618	CDD:285571	79/416 (19%)
		DHC_N2	1072..1481	CDD:285579	87/456 (19%)
		P-loop_NTPase	1621..1847	CDD:304359	93/225 (41%)
		P-loop_NTPase	1919..>1967	CDD:304359	17/54 (31%)
		P-loop_NTPase	1947..2081	CDD:304359	50/145 (34%)
		P-loop_NTPase	2565..>2733	CDD:304359	42/186 (23%)
		MT	2821..3138	CDD:289543	72/362 (20%)
		AAA_9	3179..3401	CDD:289547	53/224 (24%)
		Dynein_heavy	3536..>4051	CDD:281078	126/578 (22%)
Dhc62B	NP_995958.2	DHC_N2	678..1102	CDD:285579	96/494 (19%)
		P-loop_NTPase	1239..1469	CDD:304359	96/233 (41%)
		P-loop_NTPase	1553..1699	CDD:304359	50/145 (34%)
		P-loop_NTPase	1874..2145	CDD:304359	60/287 (21%)
		P-loop_NTPase	2249..2511	CDD:304359	54/271 (20%)
		MT	2524..2864	CDD:289543	74/371 (20%)
		AAA_9	2898..3111	CDD:289547	53/227 (23%)
		Dynein_heavy	3253..3952	CDD:281078	127/581 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	230	1.000	Domainoid score	I503
eggNOG	1	0.900	-	-		E1_COG5245
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	1	1.100	-	-	P	PTHR10676
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.810