DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btv and dhc1

DIOPT Version :9

Sequence 1:	NP_001036369.3	Gene:	btv / 35073	FlyBaseID:	FBgn0023096	Length:	4236	Species:	Drosophila melanogaster
Sequence 2:	NP_001342921.1	Gene:	dhc1 / 3361400	PomBaseID:	SPAC1093.06c	Length:	4196	Species:	Schizosaccharomyces pombe

Alignment Length:	4433	Identity:	932/4433 - (21%)
Similarity:	1718/4433 - (38%)	Gaps:	919/4433 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TKFIINTSVEYFSARLPGSELDEQTAMIL--------------EFLE-QEELTVISAVHSRSDGR 54
            ||::::.   ||:|.|....:|:::.:.|              :|.: :...|.....:..||..
pombe   152 TKYVMSC---YFTAYLAMESVDDRSTIDLNSPSKGKELELTCQKFADFERSFTFFCREYQNSDTI 213

  Fly    55 IRFHHRIPNEELCLLFYKVPQVGHHRKEDGSEPLLGILTLEGGMVKSIYNSVSRVFSPSANSARR 119
            ::.|      .|.|...|      |.:|:..:..:.:|..:.......|.|:|.:.:....:.|
pombe   214 LQHH------PLILSTIK------HAEENNLDLSVRLLPSKVLSDSEFYKSLSNLVNVWLKTTR- 265

  Fly   120 SEYGPELSGILENLHQNLGSSLGLPQSGITSLRNEIKYWQQKLGQKSSSRL-DREAAQVFIGVLE 183
                    .:::..|..:..         |:| .|..:||  ...:|.||| |:..::..:.||:
pombe   266 --------SLIKLFHDQISK---------TAL-EEFNFWQ--FYYRSLSRLNDQLHSRPVLFVLD 310

  Fly   184 NME--KQISTIDGANPSGTIEEFLDHA-------------------------------HTNLDEL 215
            .:.  |:..||...|....|:.|:|..                               ::...:.
pombe   311 ILAFGKRFHTIASFNSETNIQCFVDKVGKIDALFKEISLDIFLSSSTLESLQLSAALLYSTFSKK 375

  Fly   216 WRLPYNYPQQRMADLLDIIGKRLLEVCLTQLLAEDVWSLNSSHVNNLMSQSIDTVD-AWIQLCDS 279
            || ...||:.|:.|.::.|.:.||::....|.|....||::...::..:.|.|.:. .:|:|.|.
pombe   376 WR-NTGYPETRVLDFINFITEDLLKLISRLLPALGALSLSNVDFSHRTAVSSDILSLCYIRLKDF 439

  Fly   280 LTRLFWPNYVKHPWLGDSHVPKRGQQFKERLSEIRSIKQLYKQIATLLED-------TEL----- 332
            | |:......:..:.|..:..|:.:.|:.:|..|:|..:.::|:...|.:       |||
pombe   440 L-RISGSLKEEQSYYGLKNSIKQIKAFENKLKYIQSFHEKHQQLIGALSEVYGLTHLTELEILEH 503

  Fly   333 ----QEMFQEQAPFTE---FNIFDTSSLGQNKWHKALQHFEQVLQPIDERIAAALKRQLHNHLSN 390
                :.:|.....|.:   .|:.|.|..|.|.|:.....:...:..:::.:.|.|| .|..:...
pombe   504 LNKKEHVFNILTVFKDLQSLNVLDISLKGVNAWNSLETSYYNCMTVLEDEVIAQLK-SLLQYSKT 567

  Fly   391 PRQVIFIFSKYETLIQRPAVLELLTIEREQFLQSLHILLQDLRKA--MVDSNMEPDTGHLSVIC- 452
            ..|:.....:::.|..|..|       |......||:|:..:::.  ::.:....|.....:|.
pombe   568 SSQMFTTLMRFQPLFFRTRV-------RTSISDCLHLLVNRIKQELDLLKTRFTEDVSDTELIAM 625

  Fly   453 NECR----------WLKVVQHQIQEIEKVSHLISGR------EGFDKINKAVQEIKEETESL--- 498
            ||.|          |...:::::.|..|..::|.|.      :||        |:|.|..:|
pombe   626 NELRNLPMASSAIIWATQLKNRLHEYTKNINIIFGEDWNNFPDGF--------ELKVECITLQKR 682

  Fly   499 LRTN--FEIWSGQCSTAVKSGELRLRDDQAVV------KFEKEGRQLMRVTFNPKLVTFCQDVRE 555
            |.||  |..|...    |.|..|....|..:.      ..|...|..:.:.|:|  .:||:::|.
pombe   683 LDTNLIFTNWIND----VSSRNLNFDFDSKIFYLTQSESAESPLRLSVSIDFDP--CSFCKEIRT 741

  Fly   556 FENLGYNVPLELRAAATHAAKYMCYARRLQQIATFHNTIGDRMIPCQRPIMLKNALEL---QRLV 617
            ..:||||:|.:|...|:...:....|..|.......|.:...:...:....|....||   |.:|
pombe   742 LAHLGYNIPSQLMELASCLQRIQLIAMCLIDSVQSFNDVSFEISKTEEERFLLQEYELAVRQHIV 806

  Fly   618 QSETVAWQD-----------------------ESSVQRYVDILQAAVSKLSSDNTLLVGYHEQAK 659
            ....::|.|                       ..:|:.|.....:..|.|.:....:...:.|.:
pombe   807 TGLFISWNDFIVGNLSTPPKCAIGKRNFLKNIHPNVENYAYQFSSLTSLLMNKRNAISHTYMQIQ 871

  Fly   660 RSVLKL----MSTDLFTQNQIWKDELRHLRELVATLERQGYTHLDAF----KLHWDHQLY----K 712
            ..:.:|    .|.|:|...|      |.|::|:..|...||::|..|    .|.:...|.    |
pombe   872 EQLFQLDICEYSGDIFLTIQ------RKLQDLIDLLYVNGYSNLPPFVRALNLRFQDLLISRCRK 930

  Fly   713 VLEY--QYILGLLDMNNKL-----PDIHVKL--------VLRQRELV-FSPPEEEIRE--LY--- 756
            .|.:  ..||...:.||.|     .|::.||        :..||.:: |.||....:|  :|
pombe   931 FLSFFKTTILTSGNENNDLKSKFSSDMYEKLRGFLKPTNLTIQRNIIEFDPPVYRKKEDSIYLLD 995

  Fly   757 ----------FSQLRRFIERPCNFHG-------LSEHSQELFKSMVTVNRHHFGPLYQRAAELFD 804
                      ...::...:|.|...|       |......:|:|::    .|           ||
pombe   996 MCLQSVVNIPLLSIKTTAQRNCTLIGFFPVINRLESEILGIFESLL----FH-----------FD 1045

  Fly   805 KLQDFKTIWL---PWIALGCVDVDQLCGIHLNEAGDWDRNFRSCKHFSQQLAKLQQAEESIDCIV 866
            .:..::..|.   |::.|..:::     :..:|....|:    |...|..|..|:...:.|..:.
pombe  1046 SILGYQNYWKKVEPFLNLNSLNL-----LLKSELFQLDQ----CYSLSLYLIHLKSEVDEIGKVT 1101

  Fly   867 ------INVLPLRSDIEYISRRYWESLANSLRTAILTDVS--LIQEFLQSALQFLQNVPMDEGSI 923
                  :|....:|.: |:..|.|.:......|.:|...|  |:.|             :|:...
pombe  1102 DFKIFSVNNTEFKSQV-YLYLREWINALFDRFTFLLGKESEHLLNE-------------LDDTHS 1152

  Fly   924 SQSGMKY-----EKIMSKLPQIEK-------------TLEAVRAKDSCLGGWCKERVTALSGILL 970
            |.|.:.:     |.:::.|...:|             |.:......:....:.:...:.|..|..
pombe  1153 SLSTVDFTVNNTESLINSLKIFKKAGCYKLNVEHKIITYQNYEMTFNDCDAFSEFNFSLLKDITS 1217

  Fly   971 QWEQLQPLLENHAVILQRQVDMIKNQAETQLQNLKNEAEKFLLRW-ESTISELEANE---HSTLD 1031
            :|:.|....|...:.|:...|.|........:.:..|....:..| .|::|.::||.   .||:|
pombe  1218 KWKDLLESFECRRLKLENNKDEILRNFSEFAKRVNTETLSLISEWCASSLSLIKANYDEFSSTVD 1282

  Fly  1032 --VFKERRLHWQQLQEK------KTQLLEEC------------SKF------NMEFPAEMLTPFT 1070
              :|:..:...|.|..|      :.::.|.|            .||      |:||..|:
pombe  1283 DFLFRFSKATEQCLMVKYIKKDLEIEIEESCDFSIQTEEIHLYKKFKDVISSNLEFIVEI----- 1342

  Fly  1071 EIEEQMEKQSKQWQVYDSFLTELQPVLHEEWAIYRRRPYVLNEFIGKWEGSVHASID--LPSKRI 1133
                    ::.:|:::|:....:| ..|:..|:                .|||.|..  ......
pombe  1343 --------KNTRWKLFDTATLSVQ-TTHQINAL----------------ESVHTSFQHFKLFTNT 1382

  Fly  1134 RQQVEQLQSALPILQQLQSESLSERHWARIFQLLNHKETKPLHSILLQDILQDFDVLQSAAQEIS 1198
            :|.:.||:....:||:|:|..|...||..:|::....|......:|:.||| ..| ||:....|:
pombe  1383 KQSLNQLKDCTLLLQKLKSCPLKPVHWISLFEITKSTEQLDFEKLLVSDIL-GID-LQAHESFIT 1445

  Fly  1199 SIVRQASSEQIVRQALIELDQWSVTAQLKLITRTDASGQSVSLIKDYQEVLNKIGDNQSLLQSAN 1263
            :::..|..|..:.....|:..:...:....   ....|::. ::...||:::.:..|...|....
pombe  1446 TLLNSAVVEANLENQFNEVHSFWKNSYFSF---KSFKGRNY-IVVGCQELIDAVEKNMDSLNLIK 1506

  Fly  1264 NSAAFESFSDQAELWESRLNTLDALLSSLNHSQRRWVYLEPVFGSGTLQHEQALFKRIDKDF--- 1325
            .|..|:.........:|::..:...|:.....|:.|.:|..:|...|  :.|.|...:...|
pombe  1507 TSRHFKDGDMNITDLQSKMKIIVKFLNIWKEIQQIWTHLSAIFYEST--YIQQLLPELAASFFNS 1569

  Fly  1326 -RFVMREIEMDPRVTSLTKINNITTIVNA---LETQLARCQQNLMSYITDKRNSFPRFYFLGDDD 1386
             :..|..:.:....:.|.|::||.:::.:   |.|.|...:::|:.|...:|:...|.|||||||
pombe  1570 SKTYMHLVTLLKERSYLYKVSNIPSLLESAAKLSTTLEDSKKSLLKYFELQRHKISRLYFLGDDD 1634

  Fly  1387 LLELLGQASKDAEVIQRHIRKLFPGCHSLSIRQVGPNPATSSDVNQYSITSVHSAEGDELKLSQP 1451
            |:||:.... |..||.:.|.||:||..||.:           |....:|....:.||:||....|
pombe  1635 LMELISNPC-DPFVINKQIIKLYPGIRSLIV-----------DTENTNINGCTTNEGNELLFDNP 1687

  Fly  1452 VEMKGDIE--RWLNQLVTVVQDTL-----------RDQIYECYTGTTGGSDNLDEKILKK----- 1498
            :.:..:.:  .|::.|...::.||           ||..|           |....:..|
pombe  1688 ICLLDNTQPLHWISSLEPFLKATLFQLFSTSFQQIRDFYY-----------NKSRNVFCKEWFLR 1741

  Fly  1499 YASQVLATARALHFTRQAEQAIGSMSLGKLKQQLKDEITHLAALKNKSENGTLISLKLRALLL-- 1561
            |.||:...:.......:.|..|....|..:...:.|.|:.|..|.:::|    :|:|.:..|:
pombe  1742 YPSQITLLSLRCTLCHEIETGIADCCLDAVFNFINDGISSLVLLADENE----LSIKKKVTLMFN 1802

  Fly  1562 DLVHYSGVTEQLQKHNVVHTSDWHWLCQLRYYLGKKGGTSGEVNANRQVCVRMVYAEFEYAYEFL 1626
            :|:|:......|.|::.   :::.|..:::.:.       .|.:.:..|.::|...||.||:|:.
pombe  1803 ELLHFKETVGLLCKNSF---NNYFWSREVKAFY-------REDHDDEAVVIKMFSLEFIYAFEYS 1857

  Fly  1627 GQASKLVHTRLTHRCYLILTQAMHMGLGGNPFGPAGTGKTECVKALGAMLGRLVLVFNCDENVDT 1691
            .....:|:|.||..|:.:|..::...|||:|.|||||||||.|||:.|.||:.|.|||||...:.
pombe  1858 ELDDPIVYTDLTRNCFSVLLHSIASNLGGSPIGPAGTGKTETVKAVSAYLGKNVFVFNCDNAFNY 1922

  Fly  1692 ESMSLILTGLARCGAWGCFDEFNRLQEATLSSISMLIQPIQSALKERANSVQIGERQIQLNQHCG 1756
            :::..||:|||:.|.:.||||||||...|||:||..||.|||.:   ::|..:.:..|.|:...
pombe  1923 KTIQRILSGLAQIGTYICFDEFNRLDSGTLSAISYDIQRIQSLV---SHSDGLCQSPILLDAPT- 1983

  Fly  1757 IFVTLNPAGAEYGGRQKLPGNIQALFRPIVMQQPEPGEIARVMLFVEGFTEASAIASRIVELFEL 1821
            ||||:||.   |.||.|||.|::.|||||.|..|:..:|..::....||.| |::.|::::.|.|
pombe  1984 IFVTMNPG---YLGRFKLPSNLKKLFRPIWMGSPDNKKICEILFLSFGFKE-SSLLSQVLDSFFL 2044

  Fly  1822 --SGKMLSAQRHYDWGLRELKTVLMVCGEGLRDQLTSEDNNQSSANFEMSVVVRCLRSSTMSKLA 1884
              ||. ||...|||:|||.:|.|:...     .::......:::...|:.::...:|......|.
pombe  2045 CCSGS-LSNCLHYDFGLRAMKVVIKAA-----KRIKGFLKKKNTICQELEILWYAIREVLYPSLI 2103

  Fly  1885 PHDVNRF---EMLLRNVFPEIGSSP--AP---ETQLHQSLSAAF----AQLGLCRSERQIEKALQ 1937
            ..|:..|   |....| ||.:.::.  .|   |..:.|:||..|    ..|.|        |.:|
pombe  2104 YQDIPLFFKAEESYFN-FPAVKANAFIDPDNFEVNIEQTLSKNFFGNNQYLKL--------KIMQ 2159

  Fly  1938 LHEQLQKRMGVVLVGPPGCGKSTIISLLKQAL--CGTQLKVHTISPKSMSRIQLLGRLDADTRQW 2000
            |::..:...|::|:|..|.|||.|..:|:.||  .|....|:.||||::::..|.|.::.|||:|
pombe  2160 LYQMSEAYNGIILLGKTGSGKSQIFRILQSALLNIGIDCIVYVISPKALTKESLFGSMNMDTREW 2224

  Fly  2001 QDGVLTHTAVAVNQESSQVHSWIVCDGSIDPEWIEALNSVLDDNKLLTLPSGWRIQFGSNVNFIF 2065
            .|||.|.................|.|..:.|||:||:||:|||||.|||.:|.||.....|...|
pombe  2225 TDGVFTKLLRKTRDSCYYKRYMFVFDDELSPEWVEAMNSLLDDNKTLTLSNGERIALQPYVKIFF 2289

  Fly  2066 ETDDVRHASPATISRMGIVNMS-------------------YDYYPADG-------ILKHELSKE 2104
            |.|.|...:.|||||.|::.:|                   ...||...       :....|:.|
pombe  2290 EADSVASLTRATISRCGLICISNIDDNILSSTDKMLSFTSGATNYPLGSSNDEFSTVFSKVLTDE 2354

  Fly  2105 PYGDLLQS----YVDGNFQYAVNWIESQLLLTHLPGINRAHLLRSLLLQLHGTQSLEEYGAATLR 2165
            ...:|:.|    .||  .|:.:|:.:.:...|....:::..|.         |:|.....:.:.:
pombe  2355 VMMNLISSCYKFSVD--LQHIMNFTKQRFFTTFYSLLDQTKLF---------TRSSNITESLSFK 2408

  Fly  2166 ALFGYM---------------PNDRQRE-FAQLILKHANLYVANPNYAELTHY------------ 2202
            .|..|:               .:.:.|| |...::::|:  |..|...:..|.
pombe  2409 ELCNYLKKKICYILAWCCTGDTDAKSRERFTHWLMQNAS--VDLPEIKDFEHVSILDFDVSLETQ 2471

  Fly  2203 -------ESSRNSLEQYAVDAIETPEKGSQLIITSYMKSYLDILETLLKTQGTRLPPFMLIGPSG 2260
                   ::.::|..:||         |:.:|.|.....|.:.|...|    |:....:..||.|
pombe  2472 SWYPIAGKTLKSSALKYA---------GNTVIPTLDTVRYAEFLNFSL----TKNRCVIFCGPPG 2523

  Fly  2261 SGKTLLLQRAVLENSGYQLATINCSTQLTPRYILHTLKTHCVTVSGIKGREYR--------PK-- 2315
            |||::|:...:......::..:|.|...:.:.::..|:...|        .||        ||
pombe  2524 SGKSMLMLGTLRSRQDVEVIALNFSISTSSKSVVSFLEQSTV--------YYRSTGMTIMCPKNH 2580

  Fly  2316 QARLVLFMKNLDLCQQDSWGACEVVELLFQLAQRGGFYAE-NLEWIGVSGLQLCASIGGNT---- 2375
            :..||||...::|.:..:..|.:|:..|..:.:..||:.. :.||:.:..:.:|.:...:|
pombe  2581 EKVLVLFCDEINLPRSRNCLAEDVICFLRHMLEHQGFWHPLHKEWVTIKNIFVCGACNPSTDIGR 2645

  Fly  2376 GKIAPRYFAINQFVRVSRPTSQDMLEIVQRRLE--PLLEEHFRGSENRGRSGVNLQHVSESLMDC 2438
            .....|:......:.|..|.|..::.|....||  .|:.::          ...:.::.::.:..
pombe  2646 NDFPERFLRRTVLIFVDYPESYSLVTIYNALLEKSALINQY----------KTIILNIVKASVKF 2700

  Fly  2439 FEKLQATF-TNVGGRQAHYQFSPKCIMKLLDALVFYPAS-------DFNEALYCELLGMFRDRLI 2495
            ::.|:..| ::..|    |.::|:.:.:.|.:...|..|       ...:..|.|...:..|||:
pombe  2701 YQVLRENFKSSTQG----YVYTPRDLTRWLISFKNYAESYAETNNLSLIKVWYHEACRVLLDRLV 2761

  Fly  2496 SEE-------HVQQ--------------------FEGILKQTMRKYYGKEKVFFVPKSPKSRGHL 2533
            |::       .:|:                    |..|||.      |.|.:.|....||
pombe  2762 SQKECSWGMTELQKVIVTDFGEFEVSVIFEKQIIFTDILKN------GLEFLDFASLRPK----- 2815

  Fly  2534 HCLTHDEWMEEVQRQVTICNTENYSITAPITEELLSHVARITRVLSRTDAHMLILGQSGGRHLDA 2598
                    :|.:.::....:..|   |....:|.::|:.|..|:|:.:..|.|:.|..|......
pombe  2816 --------LESLYKKFYSSHPNN---TLVFVDETITHILRFHRILNNSGMHALLQGSVGLGQKAV 2869

  Fly  2599 IFTAATFQEAKVVTLQGGPSYDLTDFYNDLKVAMQTAALEQQMSYLLIEQCWLSYVPDILKPIEA 2663
            :..........:..||...:|.:.||.::||..:..|......:.|.|.:. ::.||..|..:..
pombe  2870 VEFVCWLNSFSLFELQKNQTYSIEDFEDNLKSILILAGTTNCKACLAINES-IAGVPGFLDLLNN 2933

  Fly  2664 LLEGSEILELFGDDLETVASTLKQAAQLEGYQ-------ESMGTYFLKRARDYLHIIIVLDPNSA 2721
            ||..||:...|  |....|...|...:|..:|       ||:...|:......|.::..: ..||
pombe  2934 LLTNSEVSNFF--DQNDWAEIKKNLNKLNEFQPLKFDSEESVTEIFMNNVFQNLCVVFYV-YTSA 2995

  Fly  2722 KVQDYFNNF-PALHRQMDLLYVRGESRETIAILPKQFIELLNESIA--------------GGGS- 2770
            .|....|:. |||..:..:.|.......::..:..   |:|.|:|:              .|.|
pombe  2996 DVDFQTNSLSPALLNRCTIDYYHSWDYHSMLQIAN---EVLQETISLNALDHDNPNLKNIKGSSI 3057

  Fly  2771 ----------------------GRGKVPTCSHFADISDELPSEETSQRYYQLIRTYFHMYNNAAN 2813
                                  |:....:|.||                .:.:.|:..::...||
pombe  3058 YDAVAQAVVNTHTSIVWEFKHLGKTSYFSCLHF----------------IRFLNTFCLIFGRDAN 3106

  Fly  2814 EIDQRLGKLQMGVDKLASAHALVDTLKSNAAAQEQALGEKRQLANEALEMISFTMRNANEQKSSM 2878
            ::.:...:::.|..|:......:|..|...:.|:..|..|.:.||:.|:.|..|.:....:|...
pombe  3107 KLSKEKSRIENGFKKIKETSQGIDKFKEALSDQQNVLFSKTKTANDRLQCIIQTKQAVEAKKVYS 3171

  Fly  2879 LELKQQTQKSSEQLKIRQKEIQQELAEVEPILAEASNAVGQIKSEALSEIRSLRAPPEAVRDILE 2943
            |:.:...||.|..|..::..:.:|::..:|.:.||..:|..||...|.|:|||..||.|:|..:|
pombe  3172 LQAEASLQKKSFLLNEKKNSVMKEVSYAKPAVIEARKSVSDIKKAHLIELRSLSRPPMAIRITME 3236

  Fly  2944 GVLRLMGIRDTSWNSMKTFL---------------------AKRGVKEDIRSLDPARISPENCEA 2987
            .|.:|:|...|.|.:::..|                     .:|.:::|..| :|.
pombe  3237 VVCKLLGFSATDWKNVQQLLKRDDFIPKILNYNLEKELSINLRRKIEQDYFS-NPI--------- 3291

  Fly  2988 VERLLLAKGDSYEAKNAKRASAAAAPLAAWVQASVRYSRVIQSIKPLEREQNELQKNLNAAEDEM 3052
                       :...:..|||.|..||..|:::...||:|::.::||..|.:.|:.....||:.:
pombe  3292 -----------FTFDSVNRASKACGPLLLWIKSICNYSKVLEKLEPLNSEVDRLKLEQKNAEECI 3345

  Fly  3053 QELASGLDDVDKRVKQLSAKLQTYTQEAAVLELKLQEASGTLQAAELLVEKLSAEYTTWSLQLTE 3117
            ||..:...|:|:::.||..:..:...|...:||::.|....:|.:..::..||.|...||..|..
pombe  3346 QETIAACKDLDEKLLQLQEEYASMISEIHSMELQMDEVKCKMQRSIEVITDLSIERNEWSGFLNL 3410

  Fly  3118 LKKAHKTLDAKTLLIAIAINYCAGLG------LEQRCSSLKRLAADFHLPSDFDLRGSLLTEQQQ 3176
            ..|....|..::|:.|..:.|...|.      |..:|   :.:.:.|..|..   :.::.|..::
pombe  3411 YPKRMWNLVGESLMEASFVVYAGNLDPSMRIFLRNKC---EPIISSFGFPIS---KSAVRTNIER 3469

  Fly  3177 IIWESQGLARDAQIIESAAL-------LREMLSLPYGACPIPLLLDPTQTAAAWLMAHLKGSGRP 3234
            .:..|         |||...       |..:..:.....|: |::||:......|.:..|  |:.
pombe  3470 CVQTS---------IESKYYKNLTDYSLENIYIIQENKSPL-LIIDPSSQILDILPSLYK--GKA 3522

  Fly  3235 CELTTHGNDRLPYQLELAVRFGKTLLVTDCEQLRPPVLQLLQGHVFVRFNKRQLAIGSKLVDLHE 3299
            .:|.:..|.....|::||:..|..:::.|.|.....:..||:...|....:.|.......:.:..
pombe  3523 SDLISFSNKSFQNQIKLALLSGSAIIIKDAELWDVSIEPLLKPEFFTGSGEVQTTFAKDTITITL 3587

  Fly  3300 SFQLVLISKSHRLDLPEEQRSQLNVLKFTVTAAGLADQLMSKAIVLKNGELEQQRIELLQKEGHL 3364
            ...::..|:....:|..:....:||:.||::.:.|..|::...|.::...:.:|:......:..:
pombe  3588 PLNIIFFSEVQSNELENKASKFMNVVNFTLSISLLETQMLKSVISVQEPGVFKQKDNCFTLKLSI 3652

  Fly  3365 LKQRMEMQDKLLEQLSKSEGDILKNEQLLESLNEIKQGSTQIDEALKQSGQIR---DTLLAQFG- 3425
            .:|...:|::||:.|..|..:|:..::::..|..:|:....|..|..:|..|.   |.|:.::.
pombe  3653 ERQIRSLQEQLLKTLCSSNENIVGTDEIVVLLKNLKEKHETIRLAYSESQSINRKVDELIRRYKL 3717

  Fly  3426 SLRELSSRAATF--YAGLIQGYELSPLVYIELFLGALSKSQRDESKVYDCLVRSVYMNLARATSR 3488
            |::...|....|  :..|.:.|..|.......|...|:....:.::.:..|:.....:|.|
pombe  3718 SIKSFLSVVVVFQHFISLKKSYSFSFNFIWSTFHQMLNVVLENRNQDFKSLIMDALRDLIR---- 3778

  Fly  3489 DSQLSLSLWVCHQAYP-DRLNPKEWELFVNNFMGSSDGSMVLSQLGKLPDCMPKEAQLKLAMLLQ 3552
                ...|::    :| ||:    ..||:..|.                 ..|||.:....:|:
pombe  3779 ----RCFLYI----FPEDRV----LFLFLLMFF-----------------FFPKETESLRKLLI- 3813

  Fly  3553 LFPDLRSK-LQLEKDYIWRGFIEAQAD-DVLPALGSSFQRVLIAQI--FRPDLMLH--------- 3604
                :..| |:||:.|:  .|.|..:| :....|.|.|.:...:.|  |..:::.:
pombe  3814 ----VNGKTLELEQSYL--NFFETCSDSNERGGLESLFFKTHASNIQNFCTEVLANTHCEEDCLK 3872

  Fly  3605 ------------QLRKVSSDLLGISPD--ASTQPSVEQLLQQSSCDRPILMVSHAENDPTTELRK 3655
                        :...:..|.|.|..|  .|..|::..|::....|.   ::.:|:
pombe  3873 LLYDLWSSAFKVEFSNIKYDFLKIINDESESRMPTIVYLMENCEIDS---LLQNAK--------- 3925

  Fly  3656 WANQKYREMAIGKG-VEKRVLSE--MRQAAIDGHWLCVKNVHLVPEFLTQMERELSEIQKSKDFR 3717
             ..|..:::.:..| .|...|::  ::.|:.:..||.:.|:||...:..::..::|. ...|:.|
pombe  3926 -IPQNIKKLTVSLGSAENESLADSYLKLASTEPLWLFINNIHLSTPWAEKLPSKMSN-HLHKNSR 3988

  Fly  3718 LWLLCESTEGFSEAAIYKCLKVRYEQPKGLKQIVMRLLQNFAAEQDQKLKNQPKSL---KMRLVY 3779
            :..|.|.........:.....:.:.:....|..::.||        :.|.....:|   :.||.:
pombe  3989 IVCLSEIHNQLPHQLLCISRSIVFNKQTSFKNNLLNLL--------ELLPTMTHTLPHNRFRLFF 4045

  Fly  3780 FV--LTAVLQQRRQFIPQGWSKYYEFGEADLKAALGIL-RMMDQQLNSGKCDWLLMQRLSEALAY 3841
            |:  |.|.|.:...|....|.:...|.::|......|| .::.:.::..:..|...:.|...:.|
pombe  4046 FLSWLHATLAEIYCFTCSSWKEPCYFDDSDFYFGTKILCNILYRNVHLEEFSWGTFKDLLLNVVY 4110

  Fly  3842 GGRVNNQRDL----EILTTYLNQFCSADVLSNRWSPLGLSLSIPTSGQLQDYYAALEKLPDTDEP 3902
            |.:|:...|.    :||...:.|| ...:.||..........:|...........:.:|||...|
pombe  4111 GPKVSASSDFIALDKILKRLIAQF-KTQISSNILLTDNFKFILPYEITFSSAKEVIGQLPDEIPP 4174

  Fly  3903 SMYGLANQAQQQR 3915
            ....:...::::|
pombe  4175 GWLDIPENSKRKR 4187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btv	NP_001036369.3	DHC_N1	200..618	CDD:285571	100/501 (20%)
		DHC_N2	1072..1481	CDD:285579	95/430 (22%)
		P-loop_NTPase	1621..1847	CDD:304359	101/227 (44%)
		P-loop_NTPase	1919..>1967	CDD:304359	15/51 (29%)
		P-loop_NTPase	1947..2081	CDD:304359	56/135 (41%)
		P-loop_NTPase	2565..>2733	CDD:304359	41/175 (23%)
		MT	2821..3138	CDD:289543	82/337 (24%)
		AAA_9	3179..3401	CDD:289547	42/228 (18%)
		Dynein_heavy	3536..>4051	CDD:281078	76/420 (18%)
dhc1	NP_001342921.1	DHC_N1	251..816	CDD:312031	122/609 (20%)
		DHC_N2	1322..1718	CDD:312039	98/445 (22%)
		DYN1	<1605..4196	CDD:227570	631/2838 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	230	1.000	Domainoid score	I503
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.800