DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btv and dnah5l

DIOPT Version :9

Sequence 1:	NP_001036369.3	Gene:	btv / 35073	FlyBaseID:	FBgn0023096	Length:	4236	Species:	Drosophila melanogaster
Sequence 2:	XP_002666734.3	Gene:	dnah5l / 335340	ZFINID:	ZDB-GENE-091204-287	Length:	4667	Species:	Danio rerio

Alignment Length:	4903	Identity:	1061/4903 - (21%)
Similarity:	1927/4903 - (39%)	Gaps:	1045/4903 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTQRTKFIINTSVEYFSARLPGSEL------DEQTAMILEFLE---------------------- 37
            :..|.:::|:...|..|  |...|:      |::..||.||..
Zfish   139 LDSRHRYLISVIAEAIS--LADMEVEEAIIADDKFYMIEEFFSANGSKSLMLFYQATESSNSGND 201

  Fly    38 -------QEELTVISAVHSRSDGRIRFHHRIPNEELCLLFYKVPQVGHHRKEDGSEPLLGILTLE 95
                   |::|.:.|..|....|:            ||.|.::............|...|:|...
Zfish   202 TSNVAKGQKKLFITSGDHEALTGQ------------CLFFLRITDKAITTTNISQEVNFGMLDCS 254

  Fly    96 GGMVKSIYNSVSRVFSPSANSARRS----------EYGPE--------------LSGILENLHQN 136
               ..||.:::..:.:...|.|.:|          :..|:              ||.::.|:.:.
Zfish   255 ---ESSILHNLEFLLTQVMNQALKSQEDWGAIKDGQMNPDVQNFLRSVDKFTFTLSSVMRNMEEK 316

  Fly   137 LG----------SSLGLPQSG---------ITSLRNEIKYWQQKLGQ--KSSSRLDREAAQV--- 177
            ..          |.:..|:..         :..|...:.||.:::.|  ..|.|:.||:..:
Zfish   317 FKLHHIPSAPDLSHIQKPEDYSYAANNSELVEDLEAVLVYWAKQIEQVLTESERIRRESDDIGPS 381

  Fly   178 ------------FIGVLENME----KQISTIDGANPSGTIEEF--LDHAHT-------------- 210
                        |..:::.::    |:|..|..|..|.|:.::  ||.:.|
Zfish   382 AELAHWKRRMITFCSLMDEIKDPYVKKIIGILHAAKSKTMSKWKELDASITIVANEAKDNVKYLS 446

  Fly   211 NLDELWRLPYNYPQQRMADLLDIIGKRLLEVCLTQLLAEDVWSLNSSHVNNLM----SQSIDTVD 271
            .||:.:.|   ..:.....:|..|.|.:..:.:...:::  :...|.|:.:|.    :|.:.|..
Zfish   447 TLDKFFEL---LEKSTPTSMLKHIPKLMNSIHMIHRVSQ--FYNTSEHMTSLFVKVTNQMVTTSK 506

  Fly   272 AWIQLCDSLTRLFWPNYVKHPWLGDSHVPKRGQQFKERLSEIRSIKQLYKQIATLLEDTELQEMF 336
            |:  ||..:|::         |..|.      ::..:|:.|...:.|.|:|....:::...|...
Zfish   507 AY--LCQGVTKV---------WELDR------KELLKRMKECIELNQEYQQCFRQMKEKIQQNPH 554

  Fly   337 QEQAPFTE---FNIFDTSSLGQNK---WHKALQHFEQVLQPID-----------ERIAAALKRQL 384
            :.|...:|   |..|||......|   ....|:.| .|||.:.           :.|.:.:|.:.
Zfish   555 ERQLELSENYIFGKFDTFCKRLEKITDMATTLEDF-SVLQFMKFEGVEKIYMRYQNIVSTIKSKT 618

  Fly   385 HNHLS--------------NPRQVIF--IFSKYETLIQRP----AVLELLT-----IEREQFLQS 424
            :|.|.              |..||::  :.:..:|.:|||    .|||||:     :.|:..|..
Zfish   619 YNVLDHRKLEFDNDYIEFRNQIQVLYQSVDALIDTWLQRPLTTEQVLELLSRFENGVGRQMDLNQ 683

  Fly   425 LHIL--------LQDLRKAMVDSNMEPDTGHLSVICNECRWLKVVQHQIQEIEKVSHLISGREGF 481
            .:::        |:.:||........| ...|:.:..:..|.|   |..::||....::.
Zfish   684 KYMVVLQRYECDLEFVRKCYQKEKDNP-VSQLTPLAGKIEWSK---HLFKKIELPMQILK----- 739

  Fly   482 DKIN--------KAVQEIKEETESLLRTNF---EIWSGQCSTAVKSGELRLRDDQAVVKFEKEGR 535
            ||::        |.::........||....   :.|       |:..||.|....|.:.......
Zfish   740 DKLDILQMPDRRKIIRSYNRLAAVLLEYEMIHQKAW-------VEGVELGLSGLNASLLTRHPTT 797

  Fly   536 QLMRVTFNPKLVTFCQDVREFENLGYNVPLELRAAATHAAKYMCYARRLQ-QIATFHNTIGDRMI 599
            :...|..:|.::...|:......||..||..:...|....:...|..:|| .:..||..:  :.|
Zfish   798 KEFYVNLDPLVLEVLQEANNMYKLGALVPDGIHDMAAKEPQLKEYRYKLQMMLKEFHAVV--KKI 860

  Fly   600 P-----CQRP--------------IMLKNALELQRLVQSETVAWQDESSVQRYV-DILQAAVS-- 642
            |     ..:|              |:...:|.:...:.....|.|:...|.:.| |||...::
Zfish   861 PGVLKSPMKPFIRSVETALSPGLTILSWTSLNIDYFIGCVYKALQELEQVLKVVTDILDCRINHT 925

  Fly   643 --KLSSDNTLLVGYHE---------------QAKRSVLKLMSTDLFTQNQIWKDELRHLRELVAT 690
              .:.|...|.:..:|               ..:|..||:.|      .|:.:..|....||...
Zfish   926 LESMCSTTLLTLPENEPVTPEMFLTHTAATISTERETLKVAS------QQVERSMLEIAEELNRM 984

  Fly   691 LERQGYTHLDAFK-LHWD-HQLYKVLE-----YQYILGLLDMNN--------------------- 727
            |:.....:|.... ||.| .|:.:.|:     :..::|.|...|
Zfish   985 LKPSERVNLKKCSCLHPDAKQMTRCLQCLPCAFYIMMGQLCQRNTEALVTATKSSLNALHRRLLA 1049

  Fly   728 ---------------KLPDIHVKLVLRQRELVFSPPEEEIREL-------------------YF- 757
                           ::|...|.:.|....:||.|..|.|:.:                   ||
Zfish  1050 ASSSYRSSSPSGATIQVPLFRVSVELAIPNIVFRPSFEHIQGILNKGVNMVLSMAKDIPLWNYFH 1114

  Fly   758 ---SQLR------------RFIERPCNFHGLSEHSQELFKSMVTVNRHHFGPLYQR----AAELF 803
               .||:            ..:.:|.....|..|..|  ...|..:.....||...    |.::.
Zfish  1115 LQQDQLQAEQVAAREHGDETVVSKPILLRSLDRHVTE--HKDVNKSLSQLVPLVSSLKADAGDIL 1177

  Fly   804 DKLQDFKTIWLPWIALGCVDVDQLCGIHLNEAGDWDRNFRSCK----HFSQQLAKLQQAEESIDC 864
            :.|..|..:|                  ..:..:..:.|....    .||.||:.....|..|..
Zfish  1178 EDLSQFSALW------------------NQDPAEQVKAFLQTNPILADFSTQLSLYSAYETQIHE 1224

  Fly   865 I--VINVLPLRSDIEYIS----------RRYWESLANSLRTAILTDVSL----IQEFLQSALQFL 913
            :  ...|.|:..:.|.:.          :|.:.:..|...:|.:|::|.    :...||..:..|
Zfish  1225 LPQTCTVGPILFETESLKMSLIQECHTWKREFGAALNQQASAGMTEISSFVDGVNRQLQRPISDL 1289

  Fly   914 QNVPMDEGSISQSGMKYEKIMSKLPQIEKTLEAVRAKDSCLGGWCKERVTALSGILLQWEQLQPL 978
            .:|....|::.:...:..:|.:.:..:|::...:...|........||:   .|::..|::|:.:
Zfish  1290 DDVRESMGALRELREEEIRIETIMGPVEESFALLNRHDLFFNDGNAERI---DGVVYAWKELKVM 1351

  Fly   979 LENHAVILQRQVDMIKNQAETQL----QNLKNEAEKFLLRWEST---ISELEANEHS-TLDVFKE 1035
            .:.    .|:::..::...:.:|    :..:...|.|...::::   ::.|...|.| .|.|::.
Zfish  1352 AKE----TQKKLSDVEPHMKAELIAGVEVFQKSVESFYGDYDNSGPGVTGLPPREASDRLQVYQA 1412

  Fly  1036 RRLHWQQLQEKKTQLLEECSKFNM---EFPAEMLTPFTEIEEQMEKQSKQWQVYDSFLTELQPVL 1097
            :   :.:|..|..........|.:   |:|     ....|:.::...||.:.:|:|.:..:....
Zfish  1413 K---FDELWRKYVTFSSGEELFGLPVGEYP-----DLHRIKRELNLLSKLYSLYNSVIDSVSGYY 1469

  Fly  1098 HEEWA----------------IYRRRPYVLNEFIGKWEGSVHASIDLPSKRIRQQVEQLQSALPI 1146
            ...||                ..|:.|..|.|    |:    |..||     ::.::......|:
Zfish  1470 DILWADLNIEKINNELLDFQNRIRKLPAALKE----WQ----AFNDL-----KKTIDDFNETCPL 1521

  Fly  1147 LQQLQSESLSERHWARIFQLLNHKETKPLHSILLQDILQDFDVLQSAAQEISSIVRQASSEQIVR 1211
            |..:.::::..|||.||..|..||......:..|:::::  ..|....::|..:...|..|:.:.
Zfish  1522 LYMMANKAMMARHWERITDLTKHKFEVEAPNFSLRNVME--APLLKCKEDIEDVCISAVKERDIE 1584

  Fly  1212 QALIE-LDQWS--------VTAQLKLITRTDASGQSVSLIKDYQEVLNKIGDNQSLLQSANNSAA 1267
            ..|.: :.:||        ...:.:|:.:...:.:.|:|::|...||.      ||:.:..|:
Zfish  1585 AKLKDVVTEWSGHQFTFATFRNRGELLLKGSDTSEKVALMEDSLMVLG------SLMSNRYNA-- 1641

  Fly  1268 FESFSDQAELWESRLNTLDALLSSLNHSQRRWVYLEPVFGSG----TLQHEQALFKRIDKDFRFV 1328
              .|....:.|..:|:....::......|..|:|||.||..|    .|..|...|:.|||.::.:
Zfish  1642 --PFKPTIQQWVQKLSNSSEVIEKWLTVQNLWLYLEAVFVGGDIAKQLPQEAKRFQNIDKSWQRI 1704

  Fly  1329 MREIEMDPRVTS-LTKINNITTIVNALETQLARCQQNLMSYITDKRNSFPRFYFLGDDDLLELLG 1392
            |:.....|.|.. ......:..::..|..||..||::|..|:..||..||||:|:.|..|||:||
Zfish  1705 MQRAHEIPGVVQCCVGDETLQQLLPHLLEQLEVCQKSLSGYLEKKRLVFPRFFFVSDPVLLEILG 1769

  Fly  1393 QASKDAEVIQRHIRKLFPGCHSLSIRQVGPNPATSSDVNQYSITSVHSAEGDELKLSQPVEMKGD 1457
            ||| |:..||.|:..||...          |.....:.|...|.|..|.||:.:.:|:|:..:|:
Zfish  1770 QAS-DSHTIQAHLLNLFDNV----------NRVVFHEKNYDQILSFQSQEGETVNMSEPINAQGN 1823

  Fly  1458 IERWLNQLVTVVQDTLRDQIYEC--YTGTTGGSDNLDEKILK---KYASQVLATARALHFTRQAE 1517
            :|.||..|:..|:.||...|.:.  ..|..|      .|:::   .:.:||........:||.||
Zfish  1824 VEAWLGMLLDGVKKTLHSIIRQAAMVIGDQG------FKLVEFQSMFPAQVGLLGIQFIWTRDAE 1882

  Fly  1518 QAIGSMSLGK------------LKQQLKDEITHLAALKNKSENGTLISLKLRALLLDLVHYSGVT 1570
            :|:......|            |..:|.|..||......:::..|||::.        ||...:.
Zfish  1883 EALQQSKADKKIMQTTNQKFLDLLNELIDMTTHDLTKMERTKYETLITIH--------VHQKDIF 1939

  Fly  1571 EQLQKHNVVHTSDWHWLCQLRYYLGKKGGTSGEVNANRQVCVRMVYAEFEYAYEFLGQASKLVHT 1635
            :.|.:.|:....|:.|..|.|:|.         ::...:..:::...||:|..|:||...:||.|
Zfish  1940 DDLVQMNIRSPLDFEWQKQSRFYF---------IDDTDRCIIQITDVEFDYCNEYLGCTDRLVIT 1995

  Fly  1636 RLTHRCYLILTQAMHMGLGGNPFGPAGTGKTECVKALGAMLGRLVLVFNCDENVDTESMSLILTG 1700
            .||.|||:.|.||:.|.:||.|.|||||||||..|.:|..||:.|:||||.:.:|...:..|..|
Zfish  1996 PLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIYKG 2060

  Fly  1701 LARCGAWGCFDEFNRLQEATLSSISMLIQPIQSALKERANSVQIGERQ-IQLNQHCGIFVTLNPA 1764
            ||:.|||||||||||::...||..:..|..:....|.:.:.....:.. :.:::..|||:|:||.
Zfish  2061 LAQSGAWGCFDEFNRIELPVLSVAAQQIYIVLQCKKNKKSQFIFTDGDVVDMDKEFGIFLTMNPG 2125

  Fly  1765 GAEYGGRQKLPGNIQALFRPIVMQQPEPGEIARVMLFVEGFTEASAIASRIVELFELSGKMLSAQ 1829
               |.|||:||.|::..||.:.|..|:...|.||.|...||.|...::.:...|::|..:.||.|
Zfish  2126 ---YAGRQELPENLKIQFRTVAMMVPDRAIIMRVKLASAGFRENQVLSRKFYTLYKLCEEQLSKQ 2187

  Fly  1830 RHYDWGLRELKTVLMVCGEGLRDQLTSEDNNQSSANFEMSVVVRCLRSSTMSKLAPHDVNRFEML 1894
            .|||:|||.:.:||...|...|...|..         |.:||:|.||...:|||...|...|..|
Zfish  2188 VHYDFGLRNILSVLRTLGAVKRSNPTEP---------EKTVVMRVLRDMNLSKLVDEDEPLFMSL 2243

  Fly  1895 LRNVFPEIGSSPAPETQLHQSLSAAFAQLGLCRSERQIEKALQLHEQLQKRMGVVLVGPPGCGKS 1959
            :.::||.|....|....|..:::....:.||......|.|.:||:|..:.|.|::.:||.|.||:
Zfish  2244 INDLFPGIMLDKAGYPDLEAAITKQAEEAGLIAHPPWILKLVQLYETQRVRHGMMTLGPSGTGKT 2308

  Fly  1960 TIISLLKQAL--CGTQLKVHTISPKSMSRIQLLGRLDADTRQWQDGVLTHTAVAVNQESSQVHSW 2022
            |.|..|.:|:  ||...|...::||:::..|:.|.||..|..|.||:.:.......:.....|.|
Zfish  2309 TCIHTLMKAMTDCGNPHKEMRMNPKAITASQMFGTLDVATNDWTDGIFSTLWRKTLKSKKGEHIW 2373

  Fly  2023 IVCDGSIDPEWIEALNSVLDDNKLLTLPSGWRIQFGSNVNFIFETDDVRHASPATISRMGIVNMS 2087
            ||.||.:|..|||.|||||||||.|||.:|.||....|...:||..::.:|||||:||.|:|.||
Zfish  2374 IVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKVVFEPHNIDNASPATVSRNGMVFMS 2438

  Fly  2088 ---YDYYPADGILKHELSKEP--YGDLLQSYVDGNFQYAVNWIES------------------QL 2129
               .|:.|   ||:..|.|.|  ..|:|.:..:..:|..:|::.:                  .|
Zfish  2439 SSVLDWQP---ILQAWLKKIPPMQADVLLAAFNSIYQDLMNFVFTAVSPKMQLLECMYIKQTIDL 2500

  Fly  2130 LLTHLPGI-----NRAHLLRSLLLQLHGTQSLEEYGAATLRALFGYMPNDRQREFAQLILKHANL 2189
            |...||.:     |.||:.|..:..:       .:.|..|..|     .||.:  .::.||..|.
Zfish  2501 LQGLLPAVEEKNLNAAHINRLFIFAV-------MWSAGALMEL-----EDRAK--MEVFLKKHNA 2551

  Fly  2190 YVANPN-YAELTHYESSRNSLEQYAVDAIETPE----KGSQLIITSYMKSYLD------ILETLL 2243
            .:..|: ..|.|.:|...:|..::.:.|...||    |.|.....|.:...:|      :::|::
Zfish  2552 RLDLPSTQGEQTIFEFLVSSTGEWDLWATRVPEYIYPKDSVPDYASILVPNVDNIRTDFLMQTIM 2616

  Fly  2244 KTQGTRLPPFMLIGPSGSGKTLLLQRAVLENSGYQ---------LATINCSTQLTPRYILHTLKT 2299
            | ||..:   :|||..|:.||::::       ||.         ..::|.|:...|.....|:::
Zfish  2617 K-QGKAV---LLIGEQGTAKTVMIK-------GYTSKYDPETNLSKSLNFSSATQPGMFQQTIES 2670

  Fly  2300 HCVTVSGIKGREYRPKQA-RLVLFMKNLDLCQQDSWGACEVVELLFQLAQRGGFYAENL--EWIG 2361
            :   :....|..|.|... ::.:|:.::::...:.||.....|::.||..:||||:...  |:..
Zfish  2671 Y---IDKRMGTTYGPPGGKKMTVFVDDINMPVINEWGDQITNEIVRQLMVQGGFYSLERPGEFTT 2732

  Fly  2362 VSGLQLCASI---GGNTGKIAPR----------------------------YFAINQ-------- 2387
            |..|||.|::   ||....|..|                            ||.:.:
Zfish  2733 VVDLQLVAAMIHPGGGRNDIPQRLKRQFCVFNCTLPSNSSIDKIFHTLASGYFCVERGFPEEVCS 2797

  Fly  2388 FVRVSRPTSQDMLEIVQRRLEPLLEEHFRGSENRGRSGVNLQHVSESLMDCFEKLQATFTNVGGR 2452
            ......||::.:.:.|:.::.|                                ..|.|
Zfish  2798 LAAALVPTTRKVWQAVKAKMLP--------------------------------SPAKF------ 2824

  Fly  2453 QAHYQFSPKCIMKLLDALVFYPASDFNEALYCE----LLGMFR--------DRLISEEHVQQFEG 2505
              ||.|:.:.:.::...::...:.      .|:    |..:||        ||.|.|:..:.|:|
Zfish  2825 --HYIFNLRDLSRIWQGILTVGSE------VCQTPQLLASLFRHECSRVIADRFIDEKDRETFDG 2881

  Fly  2506 ILKQTMRKYYGKEK----------VFFVPKSPKSRGHLHCLTHDEWMEEVQRQVTICNT------ 2554
            ||::...:.:|...          |.|:..:|:..|.    ..::..||..:......|
Zfish  2882 ILERITAQDHGPSLLEQGPWQGYFVDFLRDAPEMTGE----EPEDAEEETPKVYEPIPTFKALSE 2942

  Fly  2555 ------ENY-------SITAPITEELLSHVARITRVL--SRTDAHMLILGQSGGRHLDAIFTAAT 2604
                  |.|       ::.....|:.:.|:.:|:|::  :|.:|.::.:|.||.:.|..:.:...
Zfish  2943 RLSMFQEQYNEAVRGAAMDLVFFEDAMIHLMKISRIIRTARGNALLVGVGGSGKQSLTRLASFIA 3007

  Fly  2605 FQEAKVVTLQGGPSYDLTDFYNDLKVAMQTAALE-QQMSYL-----LIEQCWLSYVPDILKPIEA 2663
            ..::..:||.  .:|::::...|||...:.|.|| :.::::     :.::.:|.|:.::
Zfish  3008 GYQSFQITLT--RTYNVSNLIEDLKALYRIAGLEGKGVTFIFTDNDIKDEAFLEYMNNV------ 3064

  Fly  2664 LLEGSEILELFG-DDLETVASTL-----KQAAQLEGYQESMGTYFLKRARDYLHIIIVLDPNSAK 2722
             |...|:..||. |:::.:..:|     |...:.....:::..|||.|.|..||:.:...|...|
Zfish  3065 -LASGEVSNLFARDEVDEITQSLIPAMKKDLPRCPPTIDNLYNYFLSRVRSNLHVALCFSPVGEK 3128

  Fly  2723 VQDYFNNFPALHRQMDLLYVRGESRETIAILPKQFIELLNESI-AGGGSGRGKVPTCSHFADISD 2786
            ::.....||.|.....:.:.:...|:.:..:.:.|  |.|.|: ......|..|.|...|.|:..
Zfish  3129 LRSRALKFPGLISGCTVDWFQRWPRDALVAVAQHF--LSNYSLRCSDEVKRSVVQTMGTFQDMVA 3191

  Fly  2787 ELPSE----------ETSQRYYQLIRTYFHMYNNAANEIDQRLGKLQMGVDKLASAHALVDTLKS 2841
            |:.:|          .|.:.|...|:.|..:|......:.....::..|:::|..|...|:.|:.
Zfish  3192 EICTEYFQRFRRQTYVTPKSYLTFIKGYQMIYTEKIENVGVLAERMNTGLERLMEAELSVNELRV 3256

  Fly  2842 NAAAQEQALGEKRQLANEALEMISFTMRNANEQKSSMLELKQQTQKSSEQLKIRQKEIQQELAEV 2906
            ....:|:.|...:|.|.|.|..::...:.|.:.|:.:.::|.:.|...::::..:|..:.:|...
Zfish  3257 ELREKEKVLEVAKQKAGEVLLEVTAKAQAAEKVKAQVQKVKDKAQAIVDEIEGDKKVAESKLEAA 3321

  Fly  2907 EPILAEASNAVGQIKSEALSEIRSLRAPPEAVRDILEGVLRLMGIR-------------DTSWNS 2958
            :|.|..:..|:..||...::.:|.|..||..:..|::.||.|...|             ..||..
Zfish  3322 KPALEASEAALKTIKPADIATVRKLGKPPHLIMRIMDCVLLLFQRRVDGVTMDPERPCVKPSWGE 3386

  Fly  2959 MKTFLAKRGVKEDIRSLDPARISPENCEAVERLLLAKGDSYEAKNAKRASAAAAPLAAWVQASVR 3023
            ....:...|....:.:.:...|:.|..|.:...|..  :.|..:.|||.....|.|.:|.:|.|.
Zfish  3387 ALKLMNNSGFLSMLLNFNKDTITEEVVELLSPYLAM--EDYNLETAKRTCGNVAGLCSWTEAMVE 3449

  Fly  3024 YSRVIQSIKPLEREQNELQKNLNAAEDEMQELASGLDDVDKRVKQLSAKLQTYTQEAAVLELKLQ 3088
            :..:.:.:.||:......:..|..|:||:          .:..:||.||.:......|:.:..::
Zfish  3450 FFGINKEVLPLKANLKLQEARLTVAQDEL----------SRAQEQLDAKQKELDDAQAMYDAAMK 3504

  Fly  3089 EASGTLQAAE----------LLVEKLSAEYTTWSLQLTELKKAHKTLDAKTLLIAIAINYCAGLG 3143
            |....|..||          .|::.|..|...|:....:.::..|.:....||....::|.....
Zfish  3505 EKQDLLDDAEACKKKMSNAVALIDGLGGEKIRWTESSAQFERQIKDMVGDVLLATGFLSYSGPFN 3569

  Fly  3144 LEQRCSSLKRLAADF---HLPSDFDLR-GSLLTEQQQI-IWESQGLARDAQIIESAALLREMLSL 3203
            .|.|...:::...:.   |:|...:|. .::|.:...| .|..|||..|...|::..::.:
Zfish  3570 QEYRTLLMQQWKKEMDSRHIPYSENLNLINMLVDNATIGEWNLQGLPNDDLSIQNGIIVTK---- 3630

  Fly  3204 PYGACPIPLLLDPTQTAAAWLMAHLKGSGRPCELTTHGNDRLPYQLELAVRFGKTLLVTDCEQLR 3268
               |...|||:||......|:..  :......::|:..:......||..:..||.||:.|..:..
Zfish  3631 ---ASRYPLLIDPQGQGKIWIKN--REQSNDLQVTSLNHKYFRTHLEDCLSQGKPLLLEDVGEEL 3690

  Fly  3269 PPVLQLLQGHVFVRFNK-RQLAIGSKLVDLHESFQLVLISKSHRLDLPEEQRSQLNVLKFTVTAA 3332
            .|||..:....|::..| .::.:|.|.||:.|:|.|.:.:|........|..::..|:.||||..
Zfish  3691 DPVLDNILEKNFIKTGKTSKVKVGDKEVDVMETFTLYITTKLANPAYSPEINAKTGVVDFTVTMK 3755

  Fly  3333 GLADQLMSKAIVLKNGELEQQRIELLQKEGHLLKQRMEMQDKLLEQLSKSEGDILKNEQLLESLN 3397
            ||.|||:.:.|:::..|:|.:|::||::.....::..|::..||.:|:..:|.::::|.|:|.|.
Zfish  3756 GLEDQLLGRVILIEKKEMEAERVKLLEEVTSNKRKMQELESNLLYRLTSIQGSLVEDESLIEVLK 3820

  Fly  3398 EIKQGSTQIDEALKQSGQIRDTLLAQFGSLRELSSRAATFYAGLIQ------GYELSPLVYIELF 3456
            ..|..:.::.:.|..:.:....:.......|.:::|.:..|..:::      .|:.|...::.:|
Zfish  3821 VTKTTAQEVSQKLTVAAETEININHAREEYRPVATRGSILYFLIVEMSLVNVMYQTSLRQFLGIF 3885

  Fly  3457 LGALSKSQRDE------SKVYDCLVRSVYMNLARATSRDSQ----LSLSLWVCHQAYPDRLNPKE 3511
            ..::.||.:.:      ..:.:.|...|:...||....|.:    |.|:|.:..|.  ..::..|
Zfish  3886 DMSMEKSPKSQVTAKRLENIMEFLTFEVFRYTARGLYEDHKFLFTLLLALKIDLQT--KNISHNE 3948

  Fly  3512 WELFVNNFMGSSDGSMVLSQLGKLPDCMPKE-----AQLKLAML--LQLFPDLRSKLQLEKDYIW 3569
            .:.|:     ....|:.|:.:    :..||.     ..|.|..|  |..|..|.:::. ..|..|
Zfish  3949 LQTFI-----KGGASLDLNSV----EAKPKRWILDTTWLNLVQLSSLHTFATLLTQVG-RNDRAW 4003

  Fly  3570 RGFI------EAQADDVLPALGSSFQRVLIAQIFRPDLMLHQLRKVSSDLLGISPDASTQPSVEQ 3628
            :.:.      |:...|...:...:|:::|:.:.:.||..:.|.||..::.:|:.........:|.
Zfish  4004 KSWFDEATPEESPLPDGYESQLDAFRKLLLIRSWCPDRTIAQARKYIAESMGVKYAEGVILDMEA 4068

  Fly  3629 LLQQSSCDRPILMVSHAENDPTTELRKWANQK---YREMAIGKGVEKRVLSEMRQAAIDGHWLCV 3690
            :..::....|::......:|||..:.:.|..|   .|.:::|:|.|......:.|:..||.||.:
Zfish  4069 MCSEAEKRIPLVCFLSMGSDPTENIDRLAKSKGIPCRPISMGQGQEVHARRLLAQSMSDGGWLLL 4133

  Fly  3691 KNVHLVPEFLTQMERELSEIQKSKD-FRLWLLCESTEGFSEAAIYKCLKVRYEQPKGLKQIVMRL 3754
            :|.||..:||.:....::..:...| ||||:..:....|....:...:|...|.|:|:|..:.|.
Zfish  4134 QNCHLGLDFLDEGLETVTTTENIHDNFRLWVTTDVHPKFPINFLQSSIKFTNEPPQGVKAGLKRT 4198

  Fly  3755 LQNFAAEQDQKLKNQPKSLKMRLVYFVLTAVLQQRRQFIPQGWSKYYEFGEADLKAALGILR--M 3817
            ..:...|| .::.|.|:...:......|...:|:||:|.|.||:..|||.:||..:::..::  :
Zfish  4199 YNSVTQEQ-LEITNMPQWRPLFYAVAFLHTTVQERRKFGPLGWNIPYEFNQADFTSSVQFVQNHL 4262

  Fly  3818 MDQQLNSGKCDWLLMQRLSEALAYGGRVNNQRDLEILTTYLNQFCSADVLSNRWSPLGLSLSIPT 3882
            .|..:..| .:|..::.:...:.|||||.:..|..:|.|:...:.|..:.::::. .....:||.
Zfish  4263 DDIDIKRG-VNWNCLRYMLGEVQYGGRVTDDMDKRLLNTFARIWFSESMFADKFC-FYKGYTIPK 4325

  Fly  3883 SGQLQDYYAALEKLPDTDEPSMYGLANQAQQQREIEQAKRVIKELRGLHYGRGLAKD-SGGAGES 3946
            :..||||:|.::.||..|.|.::||...|....:...|...:..:..:.     .|| |.|.||:
Zfish  4326 ARMLQDYHAHIDALPLVDTPEVFGLHPNADITYQTNLANDTLSTILNIQ-----PKDSSSGEGET 4385

  Fly  3947 KGNDQLTGRQKLEQQIKPLLN-LWRKLAASCTIIQTMKEAKTDVGE-SPWALFVLAELKLGADLY 4009
            :           |..::.:.| :..||.|. .:...:|.:...:|. .|..:|:..||.....:.
Zfish  4386 R-----------ESSVQKMANEMLEKLPAD-YVPHEVKSSLQKMGAFQPMTIFLRQELDRMQRVI 4438

  Fly  4010 GIVHQTLSQMHAWLKESQEVDGS---------TLRTLAEQQIPASWLKL-WPGPGSNSAVDFLRA 4064
            |.|..||:.:      ...:||:         .|.::.:.::|.||.|: |
Zfish  4439 GRVRSTLTDL------KLAIDGTIIMSEDLRDALDSMYDARVPKSWQKISW-------------- 4483

  Fly  4065 LIVRAQAAELRF-------REQMHLDFVEDINFVQ-----VFNCENLLSCLKLLQSRKLAVSTER 4117
                 :||.|.|       |.|....:..:...:|     .||.:..|:.::        ..|.|
Zfish  4484 -----EAASLGFWFTELLERNQQFYSWTFNGRPLQFWLTGFFNPQGFLTAMR--------QETTR 4535

  Fly  4118 LELQTCGSSNLESDSSDIILKL------------AP------------LKIDGAQSGMGKSNPFY 4158
            :.|.       :..:.|.::.|            :|            |.:|||  |..|.|
Zfish  4536 MNLS-------KGWALDTVILLNDVTRMMKEDVTSPPPADIGGVYIYGLYLDGA--GWDKRN--- 4588

  Fly  4159 IKY-----KIKDEVQNVSH-----TTTSSSKYGKNSLYSTQNAESKPK-------LPLYSRSSRD 4206
            :|.     |:...:..|.|     :||.|.|...| |||.. ...||:       ..|:.|||:
Zfish  4589 VKLTESSPKVLFNLLPVVHVYAVSSTTESKKPAMN-LYSCP-VYKKPRRTDLTYIFSLFLRSSQ- 4650

  Fly  4207 KLICHLNVDIVTGTAEQILLAGTALIVE 4234
                  |.|..|       |.|.||:.:
Zfish  4651 ------NPDHWT-------LRGVALLCD 4665

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btv	NP_001036369.3	DHC_N1	200..618	CDD:285571	96/518 (19%)
		DHC_N2	1072..1481	CDD:285579	109/440 (25%)
		P-loop_NTPase	1621..1847	CDD:304359	94/226 (42%)
		P-loop_NTPase	1919..>1967	CDD:304359	17/47 (36%)
		P-loop_NTPase	1947..2081	CDD:304359	57/135 (42%)
		P-loop_NTPase	2565..>2733	CDD:304359	39/181 (22%)
		MT	2821..3138	CDD:289543	69/339 (20%)
		AAA_9	3179..3401	CDD:289547	60/222 (27%)
		Dynein_heavy	3536..>4051	CDD:281078	125/546 (23%)
dnah5l	XP_002666734.3	DHC_N1	345..896	CDD:285571	110/591 (19%)
		DHC_N2	1444..1846	CDD:285579	109/437 (25%)
		P-loop_NTPase	1981..2212	CDD:304359	96/233 (41%)
		P-loop_NTPase	2296..2431	CDD:304359	56/134 (42%)
		P-loop_NTPase	2597..2861	CDD:304359	56/323 (17%)
		P-loop_NTPase	2951..3220	CDD:304359	56/279 (20%)
		MT	3235..3580	CDD:289543	72/356 (20%)
		AAA_9	3609..3825	CDD:289547	61/224 (27%)
		Dynein_heavy	3971..4656	CDD:281078	167/759 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900