DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btv and Dnah5

DIOPT Version :9

Sequence 1:	NP_001036369.3	Gene:	btv / 35073	FlyBaseID:	FBgn0023096	Length:	4236	Species:	Drosophila melanogaster
Sequence 2:	NP_579943.3	Gene:	Dnah5 / 110082	MGIID:	107718	Length:	4621	Species:	Mus musculus

Alignment Length:	5022	Identity:	1099/5022 - (21%)
Similarity:	1950/5022 - (38%)	Gaps:	1208/5022 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTQRTKFIINTSVEYFSARLPG----------SELD----EQTAMILEFLEQEELTVISAVHSRS 51
            :|||.|    ...|...|||.|          |.||    |....:||..:.|.:..:.||
Mouse    18 LTQRLK----EEKEAKRARLDGRHDYLFAIVASCLDLNKPEVEDALLEGNQIERMDQLFAV---- 74

  Fly    52 DGRIRFHHRIPNEELCLLFY----KVPQVGHHRKEDGSEPLLGIL-------------------- 92
             |.:|.          |:||    :..:.||.....|..|..|.:
Mouse    75 -GGLRH----------LMFYYQDVEGAEAGHCGSSGGVNPASGKMKKPKVFVTEGKDVALMGACV 128

  Fly    93 --------------------------TLEGGMVKSIYNSVSRVFSPSAN---------------S 116
                                      |.:||::.|:...:|.:|.|:..               |
Mouse   129 FFIRSDPSKAITPENIHREVSFNTLDTADGGLLNSVRRLLSDIFIPALRASSHGWGELEGLQDAS 193

  Fly   117 ARRSEYGPELS---GILENLHQNLGSSLGLPQSGITSL--------------------------- 151
            :.|.|:...|.   |||.....:|...:.|.:..|..|
Mouse   194 SIRQEFLSSLEGFVGILSGAQNSLKEKVNLQKCDIIELKSLKEPTDYLALASNPETVEKVECCMR 258

  Fly   152 -------------------------RNEIKYWQQKLGQ--------KSSSRLDREAAQVFIGVLE 183
                                     |.|:::|:|:|.:        ||.   |.:||...:...:
Mouse   259 VWIKQMEQILAENSQLRKEADDVGPRAELEHWKQRLSRFNYLLDQLKSP---DVKAALALLAAAK 320

  Fly   184 N------MEKQISTIDGANPSG-------TIEEFLDHAH-----TNLDELWRL-----------P 219
            :      .:..|...|.||.:.       |:|:..|..:     |.:|.:..|           .
Mouse   321 SKLLKVWRDTDIRITDAANEAKDNVKYLYTLEKCCDPLYSSDPVTMIDAIPTLINAIKMVYSISH 385

  Fly   220 YNYPQQRMADLLDIIGKRLLEVC---LTQLLAEDVWSLNSSHVNNLMSQSIDTVDAWIQLCDSLT 281
            |....:::..|...:..:::..|   :|......:|    |....::.|.|..|   |:|.....
Mouse   386 YYNTSEKITSLFVKVTNQMISACKAHITNNGTATIW----SQPQEIVMQKIAAV---IKLKQGYQ 443

  Fly   282 RLFWPNYVK---HPW-----LGDSHVPKRGQQFKERLSEIRSIKQLYKQIATLLEDTELQEMFQE 338
            ..|.....|   :|.     ..:.::..:.:.|..||::|..|...:|.. ::|:|::::.:...
Mouse   444 SCFQETKQKLKQNPSEKQFDFSEMYIFGKFETFHRRLAKIMDIFTTFKTY-SVLQDSKIEGLEDM 507

  Fly   339 QAPF---------TEFNIFDTSSLGQNKWHKALQHFEQVLQPIDERIAAALKRQLHNHLS----- 389
            ...:         .|:|..|...:          .|:|..:...:||     .:|||.|.
Mouse   508 ATKYQDIVAAIKKKEYNFLDQREM----------DFDQDYEEFCKRI-----NELHNDLQRFMDI 557

  Fly   390 ------NPRQVIFIFSKYETL-IQRPAVLELLTIEREQFLQSLHILLQDLRKAMVD----SNMEP 443
                  :.||.:....|:|.| |....:.|...|..:.|...:..:.:...|...|    .|..|
Mouse   558 TFEKIPSTRQALSTLKKFERLNIPNLGIEEKYQIIFQNFATDIDTISKLYTKQKYDPPLARNQPP 622

  Fly   444 DTGHLSVICNECRWLKVVQHQIQE----IEKVSHLISGRE------GFDKINKAVQEIK------ 492
                   |..:..|.:.:.|::::    .::...::...|      .:::|.|.:.|.:
Mouse   623 -------IAGKILWARQLFHRLEQPMQLFQQHPFVLRTAEAKPVIRSYNRIAKVLLEFEVLYHRA 680

  Fly   493 --EETESLLRTNFEIWSG-QCSTAVK---SGELRLRDDQAVVKFEKEGRQLMRVTFNPKLVTFCQ 551
              ::.|       ||.:| :.|..||   :|||                   .|.|:|:::...:
Mouse   681 WLQQIE-------EIHAGLEASLLVKAPGTGEL-------------------FVNFDPQILVLFR 719

  Fly   552 DVREFENLGYNVPLELRAAATHAAKYMCYARR---LQQIATFHNTIGDRMIPCQRPIMLKNALEL 613
            :.:....||  :|:...|||....:.| :.:.   ::.:.:.:..:..:|.|....:|..:...:
Mouse   720 ETQCMSQLG--LPVSPFAAALFQKRDM-FKKNFSDMKMMLSEYERVKLKMPPAIEQLMFPHLARV 781

  Fly   614 QRLVQS--ETVAWQDESSVQRYVDILQAAVSKLSSDNTLLVG-------------YHEQAKRSVL 663
            ...:|.  ..:.| ...::..|   |:.|.:|: .|..||:.             ..|.:..::.
Mouse   782 DEALQPGLAVLTW-TSLNIGGY---LENAFAKI-KDLELLLDRVNDLIEFRIHAILEEMSSMALC 841

  Fly   664 KLMSTDLFTQN---QIWKD------ELRHLR---------ELVATL------------------- 691
            :|...|..|..   |:.||      :|.|.:         ||:..|
Mouse   842 QLPQDDPLTCEEFLQMTKDLCVSGAQLLHFKSSLVEEAVNELINMLLDVDVPPEEAAENVCHENA 906

  Fly   692 --------ERQGYTHL----------------------------DAFKL--HWDHQ----LYKV- 713
                    .|:|::..                            :|.:|  |::||    |.||
Mouse   907 SPSGNTSGRREGHSEALASSFNAGASSLPLTATARKKKETEVLEEARELLSHFNHQNTDALLKVT 971

  Fly   714 ----------LEYQYILGLLDMN-------NKLPDIHVKLVLRQRELVFSPPEEEIRELYFSQLR 761
                      :.:.:::...|.|       |.||.....:.|....:..:|..|:|::.....:.
Mouse   972 RNTLEAIRRRIHFSHMINFRDSNDASKAKQNHLPIFRASVTLAIPNIAMTPALEDIQQTLNKAVE 1036

  Fly   762 RFIERPCNFHGLSEHSQELFKSMVTVNRHHFGPLYQRAAELFDKLQDFKTIWLPWIALGCVDVDQ 826
            ..|..|   .|:.:.|.||....         .:::|                           :
Mouse  1037 CIISVP---KGVRQWSSELLSKR---------KMHER---------------------------K 1062

  Fly   827 LCGIHLNEAGDWDRNFRSCKHFSQQLAKLQQAE--ESIDCIVINV-LPLRSDIEY---------- 878
            :..:..||..|.|             |::::.|  |:::...||: :|:::...|
Mouse  1063 MAAVKNNEDSDSD-------------AEVEENELQETLEIASINLPIPVQTQNYYKNISDNKEIV 1114

  Fly   879 ---------IS-------------RRY---WESLANSLRTAILTDVSLIQEFLQSALQFLQNVPM 918
                     ||             :||   |:..........:....|:.|| :|.:.:.|::..
Mouse  1115 KLVSVLSTVISSTKKEVITSMDRFKRYNHIWQKEKEDTIMTFIAQNPLLPEF-ESRILYFQSLEQ 1178

  Fly   919 D---------EGSIS-----------------------QSGMKY-----------EKIMSKLPQI 940
            :         .|||:                       ....||           |:...||.:.
Mouse  1179 EINAEPEYIRVGSIALYTADLKLSLTAETKAWMAVIGRHCNRKYRAEMENILTVVEESQKKLSRP 1243

  Fly   941 EKTLEAVRAKDSCLGGWCKE-RVTALSGILLQWEQLQPLLENHAVILQRQVDMIKNQAETQLQNL 1004
            .|.|:.:|...:.|    || |...:|...    |:.|:.|::| :|.:...::..:...::..|
Mouse  1244 IKDLDDIRIAMAAL----KEIREQQISTDF----QVGPIEESYA-LLNKYGLLVAKEEMDKVDTL 1299

  Fly  1005 KNEAEKFLLRWESTISELEANEH-------STLDVFKERRLHWQQLQEKKTQLLEECSKFNMEF- 1061
            :...||.|.|.....:||.|.:.       ||::||                 |::|.:|.:::
Mouse  1300 RYAWEKLLARASDVQNELGALQPSFRKELISTVEVF-----------------LQDCQQFYLDYD 1347

  Fly  1062 ----------PAEM-------------------------------LTPF---TEIEEQMEKQSKQ 1082
                      |.|.                               :||:   .||:.|:....|.
Mouse  1348 LNGPMASGLKPQEASGRLIIFQNQFDNIYRKYITYTGGEELFGLPVTPYPQLLEIKRQLNLLQKI 1412

  Fly  1083 WQVYDSFLTELQPVLHEEWAIY----------------RRRPYVLNEFIGKWEGSVHASIDLPSK 1131
            :.:|::.:..:.......|:..                |:.|..|.:    |:    |.:||
Mouse  1413 YSLYNNVIETVNSYQDTLWSDVNIEKINNELLEFQNRCRKLPRALKD----WQ----AFLDL--- 1466

  Fly  1132 RIRQQVEQLQSALPILQQLQSESLSERHWARIFQLLNH-----KETKPLHSILLQDILQDFDVLQ 1191
              ::.::......|:|:.:.|.::.||||.||..|..|     .||..|.:|:...:|:
Mouse  1467 --KKTIDDFSECCPLLEYMASNAMVERHWQRITALTGHSLDVGNETFKLRNIMEAPLLK------ 1523

  Fly  1192 SAAQEISSI----VRQASSEQIVRQALIELDQWSVT-----AQLKLITRTDASGQSVSLIKDYQE 1247
             ..:||..|    |::...||.:||.:.|.|..::|     .:.:|:.|.|::.:.::.::|...
Mouse  1524 -YKEEIEDICISAVKERDIEQKLRQVINEWDNKTLTFSGFKTRGELLLRGDSTSEVIASMEDSLM 1587

  Fly  1248 VLNKIGDNQSLLQSANNSAAFESFSDQAELWESRLNTLDALLSSLNHSQRRWVYLEPVFGSG--- 1309
            :|.      |||.:..|.    .|..|.:.|...|:....::.:....|..|:|||.||..|
Mouse  1588 LLG------SLLSNRYNM----PFKAQIQKWVQCLSNSTDIIENWMTVQNLWIYLEAVFVGGDIA 1642

  Fly  1310 -TLQHEQALFKRIDKDFRFVMREIEMDPRVTSLTKINNITTIVNA-------------LETQLAR 1360
             .|..|...|..|||.:            |..:|:.:.|..:|..             |..||..
Mouse  1643 KQLPKEAKRFSNIDKSW------------VKIMTRAHEIPNVVQCCVGDETMGQLLPHLLDQLEI 1695

  Fly  1361 CQQNLMSYITDKRNSFPRFYFLGDDDLLELLGQASKDAEVIQRHIRKLFPGCHSLSIRQVGPNPA 1425
            ||::|..|:..||..||||:|:.|..|||:||||| |:..||.|:..:|....::...
Mouse  1696 CQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQAS-DSHTIQAHLLNVFDNIKTVKFH------- 1752

  Fly  1426 TSSDVNQYSITSVHSAEGDELKLSQPVEMKGDIERWLNQLVTVVQDTLRDQIYECYTGTTGGSDN 1490
               |.....|.|:.|.||:.::|.:||..:|::|.|||.|:...|.:|...|.:       .:.|
Mouse  1753 ---DKIYDRILSISSREGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQ-------AAAN 1807

  Fly  1491 LDE------KILKKYASQVLATARALHFTRQAEQAIGSMS-----LGKLKQQLKDEITHLAALKN 1544
            :.|      :.|..:.:||......:.:||.:|:|:.:..     :.|..|...:.:..|..:..
Mouse  1808 IQEPGFQLIEFLSSFPAQVGLLGIQMLWTRDSEEALRNAKFDKKIMQKTNQAFLELLNMLIEITT 1872

  Fly  1545 KSENGTLISLKLRALLLDLVHYSGVTEQLQKHNVVHTSDWHWLCQLRYYLGKKGGTSGEVNANRQ 1609
            | :..::..:|...|:...||...:.:.|...:|...:|:.||.|.|:|..:.         :.:
Mouse  1873 K-DLSSMERVKYETLITIHVHQRDIFDDLCHMHVKSPTDFEWLKQCRFYFKED---------SDK 1927

  Fly  1610 VCVRMVYAEFEYAYEFLGQASKLVHTRLTHRCYLILTQAMHMGLGGNPFGPAGTGKTECVKALGA 1674
            ..:.:....|.|..||||...:||.|.||.|||:.|.||:.|.:||.|.|||||||||..|.:|.
Mouse  1928 TMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGR 1992

  Fly  1675 MLGRLVLVFNCDENVDTESMSLILTGLARCGAWGCFDEFNRLQEATLSSISMLIQPIQSALKERA 1739
            .||:.|:||||.:.:|...:..|..|||:.|:|||||||||:....||..:..|..|.:..||..
Mouse  1993 CLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHK 2057

  Fly  1740 NS-VQIGERQIQLNQHCGIFVTLNPAGAEYGGRQKLPGNIQALFRPIVMQQPEPGEIARVMLFVE 1803
            .| :......:.:|...|:|:|:||.   |.|||:||.|::..||.:.|..|:...|.||.|...
Mouse  2058 KSFIFTDGDNVTMNPEFGLFLTMNPG---YAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASC 2119

  Fly  1804 GFTEASAIASRIVELFELSGKMLSAQRHYDWGLRELKTVLMVCGEGLRDQLTSEDNNQSSANFEM 1868
            ||.:...:|.:...|::|..:.||.|.|||:|||.:.:||...|...|         .|..:.|.
Mouse  2120 GFIDNVVLARKFFTLYQLCEEQLSKQVHYDFGLRNILSVLRTLGAAKR---------ASPTDTES 2175

  Fly  1869 SVVVRCLRSSTMSKLAPHDVNRFEMLLRNVFPEIGSSPAPETQLHQSLSAAFAQLGLCRSERQIE 1933
            ::|:|.||...:|||...|...|..|:.::||.|....|...:|..::|....:.||........
Mouse  2176 TIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELETAISKQVEEAGLINHPPWKL 2240

  Fly  1934 KALQLHEQLQKRMGVVLVGPPGCGKSTIISLLKQAL--CGTQLKVHTISPKSMSRIQLLGRLDAD 1996
            |.:||.|..:.|.|::.:||.|.||:|.|..|.:|:  ||...:...::||:::..|:.||||..
Mouse  2241 KVIQLFETQRVRHGMMTLGPSGSGKTTCIHTLMKAMTDCGKPHREMRMNPKAITAPQMFGRLDVA 2305

  Fly  1997 TRQWQDGVLTHTAVAVNQESSQVHSWIVCDGSIDPEWIEALNSVLDDNKLLTLPSGWRIQFGSNV 2061
            |..|.||:.:.......:.....|.|||.||.:|..|||.|||||||||.|||.:|.||....|.
Mouse  2306 TNDWTDGIFSTLWRKTLKAKKGEHIWIVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNC 2370

  Fly  2062 NFIFETDDVRHASPATISRMGIVNMS---YDYYP-ADGILK----------HELSKEPYGDLLQS 2112
            ..:||..::.:|||||:||.|:|.||   .|:.| .:|.||          .:|..|.:.||.:.
Mouse  2371 KIVFEPHNIDNASPATVSRNGMVFMSSSVLDWSPILEGFLKRRSPQEAEILRQLYAETFPDLYRF 2435

  Fly  2113 YVDGNFQYAVNWIESQLLL--TH-LPG----------INRAHLLR----------SLLLQLHGTQ 2154
            .:. |.::.:..:|:.::.  || |.|          ::..||.|          ..:|:|.|.:
Mouse  2436 SIQ-NLEFKMEVLEAFVITQSTHMLQGLIPPKEQAGEVDPEHLGRLFVFAMMWSVGAVLELEGRR 2499

  Fly  2155 SLEEY----GAATLR---------ALFGY--MPNDRQREFAQLILKHANLYVANPNYAELTHYES 2204
            .:|.:    ...||.         .:|.|  .||...|.::          :..|.|.
Mouse  2500 RMELWLRSREGPTLHLPQLTDAGDTMFDYYVAPNGTWRHWS----------LCTPEYV------- 2547

  Fly  2205 SRNSLEQYAVDAIETPEKGSQLIITSYMKSYLDILET--LLKTQGTRLPPFMLIGPSGSGKTLLL 2267
                   |..|.  |||.||.|:      ..:|.:.|  |:||...:....:|||..|:.||:::
Mouse  2548 -------YPPDT--TPEYGSILV------PNVDNVRTDFLIKTIAKQGKAVLLIGEQGTAKTVII 2597

  Fly  2268 Q--RAVLENSGYQLATINCSTQLTPRYILHTLKTHCVTVSGIKGREYRPKQA-RLVLFMKNLDLC 2329
            :  .:..:...:.:..:|.|:..||.....|::::   |....|..|.|... ::.:|:.:|::.
Mouse  2598 KGFMSKFDPESHMVKNLNFSSATTPVMFQRTIESY---VDKRMGTTYGPPAGKKMAVFIDDLNMP 2659

  Fly  2330 QQDSWGACEVVELLFQLAQRGGFYAENL----EWIGVSGLQLCASI---GGNTGKIAPRYFAINQ 2387
            ..:.||.....|::.||.::.|||  ||    |:..:..:|..|::   ||....|..|......
Mouse  2660 VINEWGDQVTNEIVRQLMEQSGFY--NLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFS 2722

  Fly  2388 FVRVSRPTSQDMLEIVQRRLEPLLEEHFRGSENRGRSGVNL----QHVSESLMDCFEKL------ 2442
            ....:.|:...|.:|.                  |..|...    :..||.:.|...||
Mouse  2723 IFNCTLPSDASMDKIF------------------GVIGAGYYCAQRGFSEEVQDALIKLVPLTRR 2769

  Fly  2443 --QATFTNVGGRQA--HYQFSPKCIMKLLDALVFYPA---SDFNEALYC---ELLGMFRDRLISE 2497
              |.|...:....|  ||.|:.:.:.::...::...:   .|.:|.|..   |...:..||....
Mouse  2770 LWQMTKLKMLPTPAKFHYVFNLRDLSRIWQGMLNITSEVIKDTDELLRLWKHECKRVIADRFSMS 2834

  Fly  2498 EHVQQFEGILKQTMRKYYGKEK------------VFFVPKSPKSRGHLHCLTHDE---WMEEVQR 2547
            ..|..|:..:...:.:.:|:||            |.|:..:|::.|.    |.:|   .|.::..
Mouse  2835 SDVTWFDKAVVSLVEEEFGEEKAPVVDCGVDAYFVDFLRDAPEATGE----TPEEADAEMPKLYE 2895

  Fly  2548 QVTICN--TENYSITAPITEE--------------LLSHVARITRVL--SRTDAHMLILGQSGGR 2594
            .:...|  .|..|:...:..|              .:.|:.:|:||:  .|.:|.::.:|.||.:
Mouse  2896 PIASLNHLRERLSVFLQLYNESIRGTGMDMVFFIDAMVHLVKISRVIRTPRGNALLVGVGGSGKQ 2960

  Fly  2595 HLD--AIFTA--ATFQEAKVVTLQGGPSYDLTDFYNDLKVAMQTAALE-QQMSYL-----LIEQC 2649
            .|.  |.|.|  .:||    :||.  .||:.::...||||..:||..: :.::::     :.|:.
Mouse  2961 SLTRLASFIAGYTSFQ----ITLT--RSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKEES 3019

  Fly  2650 WLSYVPDILKPIEALLEGSEILELFG-DDLETVASTL-----KQAAQLEGYQESMGTYFLKRARD 2708
            :|.|:.::       |...|:..||. |:::.:.|.|     |:..:.....:::..||:.|.|.
Mouse  3020 FLEYMNNV-------LSSGEVSNLFARDEIDEINSDLTPIMKKEHPRRPPTNDNLYEYFMSRVRG 3077

  Fly  2709 YLHIIIVLDPNSAKVQDYFNNFPALHRQMDLLYVRGESRETIAILPKQFI---------ELLNES 2764
            .|||::...|...|.::....||||.....:.:.....::.:..:.:.|:         |:..|.
Mouse  3078 NLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLSSYTIDCTAEIKKEL 3142

  Fly  2765 IAGGGSGR-GKVPTCSHFADISDEL--PSEETSQRYYQLIRTYFHMYNNAANEIDQRLGKLQMGV 2826
            :...||.: |....|   ||.....  .:..|.:.|...|:.|..:|.....|:.....::..|:
Mouse  3143 VQCMGSFQDGVAEKC---ADYFQRFRRSTHVTPKSYLSFIQGYKFIYEEKHMEVQSLANRMNTGL 3204

  Fly  2827 DKLASAHALVDTLKSNAAAQEQALGEKRQLANEALEMISFTMRNANEQKSSMLELKQQTQKSSEQ 2891
            :||..|...|..|....|.:|:.|....:.|:..|:.::...:.|.:.|:.:.::|.:.|...:.
Mouse  3205 EKLKEASESVAALSKELAGKEKELQVANEKADTVLKEVTMKAQAAEKVKAEVQKVKDKAQAIVDS 3269

  Fly  2892 LKIRQKEIQQELAEVEPILAEASNAVGQIKSEALSEIRSLRAPPEAVRDILEGVLRLM------- 2949
            :...:...:::|...:|.|.||..|:..||...::.:|:|..||..:..|::.||.|.
Mouse  3270 ISKDKAIAEEKLEAAKPALEEAEAALQTIKPSDIATVRTLGRPPHLIMRIMDCVLLLFQRRVNAV 3334

  Fly  2950 ------GIRDTSWNSMKTFLAKRGVKEDIRSLDPARISPENCEAVERLLLAKGDSYEAKNAKRAS 3008
                  |....||......:......::::......|:.|..|.:....  :...|..:.|||..
Mouse  3335 KIDVDKGCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLNPYF--EMSDYNIETAKRVC 3397

  Fly  3009 AAAAPLAAWVQASVRYSRVIQSIKPLER----EQNE---LQKNLNAAEDEMQELASGLDDVDKRV 3066
            ...|.|.:|.:|...:..:.:.:.||:.    ::|.   ..::|..|:.|:....:.||.|....
Mouse  3398 GNVAGLCSWTKAMASFFSINKEVLPLKANLIVQENRHILAMQDLQKAQAELDAKQAELDVVQAEY 3462

  Fly  3067 KQLSAKLQTYTQEAAVLELKLQEASGTLQAAELLVEKLSAEYTTWSLQLTELKKAHKTLDAKTLL 3131
            :|..|:.||..::|.....|:|.||       .|:..|:.|...|:.|..|.....|.|....||
Mouse  3463 EQAMAEKQTLLEDADRCRHKMQTAS-------TLISGLAGEKERWTEQSKEFAAQTKRLVGDVLL 3520

  Fly  3132 IAIAINYCAGLGLEQRCSSL-----KRLAADFHLPSDFDLRGSLLTEQQQIIWESQGLARDAQII 3191
            ....::|......|.|...|     :..|......:..:|...|:.......|..|||..|...|
Mouse  3521 ATAFLSYSGPFNQEFRDLLLHDWKKEMKARKIPFGNGLNLNEMLIDAPTISEWNLQGLPNDDLSI 3585

  Fly  3192 ESAALLREMLSLPYGACPIPLLLDPTQTAAAWLMAHLKGSGRPCELTTHGNDRLPYQLELAVRFG 3256
            ::..::.:       |...|||:||......|:..  |.|....::|:..:......||.::..|
Mouse  3586 QNGIIVTK-------ASRYPLLIDPQTQGKIWIKN--KESQNELQITSLNHKYFRNHLEDSLSLG 3641

  Fly  3257 KTLLVTDC-EQLRPPVLQLLQGHVFVRFNKRQLAIGSKLVDLHESFQLVLISKSHRLDLPEEQRS 3320
            :.||:.|. |:|.|.:..:|:.:.....:..::.:|.|.||:.:.|:|.:.:|........|..:
Mouse  3642 RPLLIEDVGEELDPALDNVLEKNFIKTGSTFKVKVGDKEVDVMDGFKLYITTKLPNPAYTPEISA 3706

  Fly  3321 QLNVLKFTVTAAGLADQLMSKAIVLKNGELEQQRIELLQKEGHLLKQRMEMQDKLLEQLSKSEGD 3385
            :.:::.||||..||.|||:.:.|:.:..|||::|..||:......::..|::|.||.:|:.::|.
Mouse  3707 RTSIIDFTVTVKGLEDQLLGRVILTEKQELEKERTHLLEDVTANKRRMKELEDNLLYRLTSTQGS 3771

  Fly  3386 ILKNEQLLESLNEIKQGSTQIDEALKQSGQIRDTLLAQFGSLRE----LSSRAATFYAGLI---- 3442
            ::::|.|:..|:..|:.:.::.:.|:.||:..    .|..|.||    :::|.:..|. ||
Mouse  3772 LVEDESLIIVLSNTKKTAEEVTQKLEISGETE----IQINSAREEYRPVATRGSILYF-LITEMR 3831

  Fly  3443 ---QGYELSPLVYIELFLGALSKSQRDE------SKVYDCLVRSVYMNLARATSRDSQLSLSLWV 3498
               :.|:.|...::.||..:|::|.:..      :.:.:.:...|:...||....:.:...:|.:
Mouse  3832 LVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVFKYAARGLYEEHKFLFTLLL 3896

  Fly  3499 CHQAYPDRLNPKEWELFVNNFMGSSDGSMVLSQLGKLPDCMPKEAQLKLAML---------LQLF 3554
            ..:....| |..:.|.|:....|.:...        |..|.||.::..|.|.         |:.|
Mouse  3897 TLKIDIQR-NLVKHEEFLTLIKGGASLD--------LKACPPKPSKWILDMTWLNLVELSKLKQF 3952

  Fly  3555 PDLRSKLQLEKDYIWRGFIEAQ--ADDVLP-ALGSS---FQRVLIAQIFRPDLMLHQLRKVSSDL 3613
            .|:..::. ..:.:||.:.:.:  .::.|| |...|   |:|:|:.:.:.||..:.|.||...|.
Mouse  3953 SDILDQIS-RNEKMWRVWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIMDS 4016

  Fly  3614 LGISPDASTQPSVEQLLQQSSCDRPILMVSHAENDPTTE---LRKWANQKYREMAIGKGVEKRVL 3675
            :|.:........:|:..::|....|::.:....:|||..   |.|....:.|.:::|:|.|....
Mouse  4017 MGENYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVHAR 4081

  Fly  3676 SEMRQAAIDGHWLCVKNVHLVPEFLTQMERELSEIQKSKD-FRLWLLCESTEGFSEAAIYKCLKV 3739
            ..:.|...:|.|:.::|.||..:||.::...::|.:...| ||||:..|..:.|....:...:|.
Mouse  4082 KLLHQTMANGGWVLLQNCHLGLDFLDELMDVVTETETVHDTFRLWITTEVHKQFPITLLQMSIKF 4146

  Fly  3740 RYEQPKGLKQIVMRLLQNFAAE-QDQKLKNQPKSLKMRLVYFVLTAVLQQRRQFIPQGWSKYYEF 3803
            ..|.|:||:..:.|.....:.: .|..:..|.|.:...:.:  |.:.:|:||:|.|.||:..|||
Mouse  4147 ANEPPQGLRAGLRRTYGGVSQDLLDVSVGAQWKPMLYAVAF--LHSTVQERRKFGPLGWNIPYEF 4209

  Fly  3804 GEADLKAALGILR--MMDQQLNSGKCDWLLMQRLSEALAYGGRVNNQRDLEILTTYLNQFCSADV 3866
            .:||..|.:..::  :.|..:..| ..|..::.:...:.|||||.:..|..:|.|:...:.|
Mouse  4210 NQADFNATVQFIQNHLDDMDVKKG-VSWTTVRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFS--- 4270

  Fly  3867 LSNRWSP---LGLSLSIPTSGQLQDYYAALEKLPDTDEPSMYGLANQAQQQREIEQAKRVIKELR 3928
             .|.:.|   .....:||....:..|...::.||..|.|.::||...|....:.:.||.|:..:.
Mouse  4271 -ENMFGPDFTFYQGYNIPKCSTVDGYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTIL 4334

  Fly  3929 GLHYGRGLAKDSGGAGESK--------GNDQLTGRQKLEQQIKPLLNLWRKLAASCTIIQTMKEA 3985
            |:.     .|||.|.|:..        .:|.|   :||.:...|.               .:||.
Mouse  4335 GIQ-----PKDSSGGGDETREAVVARLADDML---EKLPEDYSPF---------------EVKER 4376

  Fly  3986 KTDVGE-SPWALFVLAELKLGADLYGIVHQTLSQMHAWLKESQEVDGS---------TLRTLAEQ 4040
            ...:|. .|..:|:..|:.....:..:|..||:::      ...|||:         .|..:.:.
Mouse  4377 LQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTEL------KLAVDGTIIMSENLRDALDCMFDA 4435

  Fly  4041 QIPASWLKL-WPGPGSNSAVDFLRALIVRAQAAELRFREQMHLDFVEDINFVQVFNCENLLSCLK 4104
            :|||.|.|. |  ..|.....|...|....|........:.|..::...     ||.:..|:.::
Mouse  4436 RIPARWKKASW--VSSTLGFWFTELLERNCQFTSWVSNGRPHCFWMTGF-----FNPQGFLTAMR 4493

  Fly  4105 --LLQSRKLAVSTERLELQTCGSSNLESDSSDIILKLAP---------LKIDGAQSGMGKSNPFY 4158
              :.::.| ..:.:.:.|....:..::.|.|      ||         |.::||  |..|.|...
Mouse  4494 QEITRANK-GWALDNMVLCNEVTKFMKDDIS------APPTEGVYVYGLYLEGA--GWDKRNMKL 4549

  Fly  4159 I--KYKIKDEVQNVSHTTTSSSKYGKNSLYSTQNAESKPKL---PLYSRSSRDKLICHLNVDIVT 4218
            |  |.|:..|:..|..            :::..|....|:|   |:|.:..|..|.....||:.|
Mouse  4550 IESKPKVLFELMPVIR------------IFAENNTARDPRLYCCPIYKKPVRTDLNYIAAVDLKT 4602

  Fly  4219 GTA-EQILLAGTALIVE 4234
            ..| |..:|.|.||:.:
Mouse  4603 AQAPEHWVLRGVALLCD 4619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btv	NP_001036369.3	DHC_N1	200..618	CDD:285571	82/494 (17%)
		DHC_N2	1072..1481	CDD:285579	116/455 (25%)
		P-loop_NTPase	1621..1847	CDD:304359	97/226 (43%)
		P-loop_NTPase	1919..>1967	CDD:304359	16/47 (34%)
		P-loop_NTPase	1947..2081	CDD:304359	57/135 (42%)
		P-loop_NTPase	2565..>2733	CDD:304359	48/199 (24%)
		MT	2821..3138	CDD:289543	73/336 (22%)
		AAA_9	3179..3401	CDD:289547	59/222 (27%)
		Dynein_heavy	3536..>4051	CDD:281078	131/558 (23%)
Dnah5	NP_579943.3	Stem. /evidence=ECO:0000250	1..1938		392/2154 (18%)
		DHC_N1	248..802	CDD:285571	98/616 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	901..921		2/19 (11%)
		DHC_N2	1402..1804	CDD:285579	116/461 (25%)
		P-loop_NTPase	1939..2170	CDD:304359	99/242 (41%)
		AAA 1. /evidence=ECO:0000250	1939..2161		97/224 (43%)
		AAA 2. /evidence=ECO:0000250	2221..2440		79/219 (36%)
		P-loop_NTPase	2254..2389	CDD:304359	56/134 (42%)
		AAA 3. /evidence=ECO:0000250	2547..2800		63/297 (21%)
		P-loop_NTPase	2558..2822	CDD:304359	60/292 (21%)
		AAA 4. /evidence=ECO:0000250	2913..3167		59/269 (22%)
		P-loop_NTPase	2914..3183	CDD:304359	62/284 (22%)
		Stalk. /evidence=ECO:0000250	3182..3479		62/298 (21%)
		MT	3199..3543	CDD:289543	77/352 (22%)
		AAA 5. /evidence=ECO:0000250	3564..3794		61/238 (26%)
		AAA_9	3572..3788	CDD:289547	60/224 (27%)
		Dynein_heavy	3929..4610	CDD:281078	168/745 (23%)
		AAA 6. /evidence=ECO:0000250	4009..4223		55/215 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710