DRSC/TRiP Functional Genomics Resources

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Protein Alignment CadN2 and Pcdhb17

DIOPT Version :9

Sequence 1:NP_001036368.2 Gene:CadN2 / 35071 FlyBaseID:FBgn0262018 Length:1799 Species:Drosophila melanogaster
Sequence 2:NP_444372.2 Gene:Pcdhb17 / 93888 MGIID:2136754 Length:799 Species:Mus musculus


Alignment Length:630 Identity:169/630 - (26%)
Similarity:266/630 - (42%) Gaps:140/630 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   124 INVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQGIDPD--- 185
            :.|.|:||..|||            .:|.:..|||:.:|. ||. .|:|       ..:|.|   
Mouse   121 LRVMDINDYSPVF------------SEREMILRILENSAL-GDT-FPLN-------NALDSDVAI 164

  Fly   186 -------NPANSKFDI---NRTTG----DIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYA 236
                   ..:||.|.:   ||:.|    ::.:.|.|||::   .|:.|.|:.|.|.|.....|.|
Mouse   165 NNIQTYRLSSNSHFLVVTRNRSDGRKYPELVLEKELDREE---EPELRLTLTALDGGAPPRSGTA 226

  Fly   237 DIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEE 301
            .:.:.:.|||||||:|.|..|...:.||...||.|:|:||.|.|   .....|::|::.:   ..
Mouse   227 QVLIEVVDINDNAPKFQQPTYRVQIPENSPTGSLVLTVSANDLD---SGDYGKVLYALSQ---PS 285

  Fly   302 ETGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIRVKDLNDMPPQFTK 366
            |..:...|:.|.||.|:... .:|.|..|.|.:.:.|.|||||.|..|..::|.|:||..|:...
Mouse   286 EDISKTLEVNPVTGEIRLRK-EVDFETIPSYEVDIKATDGGGLSGKCTLLLKVVDVNDNAPEVML 349

  Fly   367 DEWVTEVDETNGTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGADKFAMVRNGDGTGSLKIIQ 431
            ....:.|.|.:    |:..:...:|:|.|..|                     ||      |:|.
Mouse   350 SALTSPVPENS----PDEVVAVFSVKDPDSAN---------------------NG------KMIA 383

  Fly   432 PLDYEDP--LQSSGFRFRIQVNDKGDDGPGGSDKYHVAYS-------------WVVVKLRDINDN 481
            .::.:.|  |:|||..|...|..:..|.. ..:||::..:             .:.|::.|.|||
Mouse   384 SIEEDLPFLLKSSGKNFYTLVTKRALDRE-EREKYNITITVSDLGTPRLTTQHTITVQVSDTNDN 447

  Fly   482 VPKFDREHIEVSIYEDTK----VGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAI------ 536
            .|.|::....:.:.|:..    :|||    .|||:|.|.:|.::|.::.|  ...|.|:      
Mouse   448 APAFNQTSYTLFVRENNSPAMHIGTI----SATDSDAGSNSHISYSLLPS--HDPQLALDSLISI 506

  Fly   537 -SDRGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQDYKPT--- 597
             :|.|.:...|.||.|........:.|||.||||.::.|.:.|:|.|.|||||......:.:   
Mouse   507 NADNGQLFALRALDYEALQAFEFHVGAIDQGSPALSSQALVRVVVLDDNDNAPFVLYPMQNSSAP 571

  Fly   598 ----LPENVS-GKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKA---GFKVEYDRRGDNEN 654
                ||.... |..:.:|.|.|.|.   |.....:|:|       :||   |....:...|:   
Mouse   572 CTELLPRAAEPGYLVTKVVAVDRDS---GQNAWLSFQL-------LKATEPGLFSVWAHNGE--- 623

  Fly   655 GVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGD 699
                :.:.|.........:.:.:.:||||.|..:.:.||.|.:.|
Mouse   624 ----VRTTRLLSERDVPKHRLVLLVKDNGDPPRSASVTLHVLVVD 664

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CadN2NP_001036368.2 Cadherin_repeat 41..132 CDD:206637 3/7 (43%)
Cadherin_repeat 140..248 CDD:206637 32/124 (26%)
Cadherin_repeat 256..359 CDD:206637 33/102 (32%)
Cadherin_repeat 379..481 CDD:206637 22/116 (19%)
Cadherin_repeat 489..586 CDD:206637 32/107 (30%)
Cadherin_repeat 594..703 CDD:206637 24/117 (21%)
Cadherin_repeat 724..801 CDD:206637
EGF_CA 977..1010 CDD:238011
LamG 1013..1198 CDD:238058
EGF_2 <1233..1259 CDD:285248
Laminin_G_2 1293..1428 CDD:280389
EGF_CA 1497..1535 CDD:238011
Cadherin_C 1583..1719 CDD:279398
Pcdhb17NP_444372.2 Cadherin_2 33..112 CDD:285466
Cadherin_repeat 137..238 CDD:206637 31/112 (28%)
Cadherin_repeat 246..343 CDD:206637 34/103 (33%)
Cadherin_repeat 356..447 CDD:206637 24/122 (20%)
Cadherin_repeat 455..557 CDD:206637 32/107 (30%)
Cadherin_repeat 576..664 CDD:206637 23/104 (22%)
Cadherin_C_2 687..770 CDD:293101
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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