Protein Alignment CadN2 and cdh1

DIOPT Version :9

• Sequence 1: NP_001036368.2
• Gene: CadN2 / 35071
• FlyBaseID: FBgn0262018
• Length: 1799
• Species: Drosophila melanogaster
• Sequence 2: XP_002936043.5
• Gene: cdh1 / 779546
• XenbaseID: XB-GENE-12531594
• Length: 872
• Species: Xenopus tropicalis
• Alignment Length: 954
• Identity: 239/954 - (25%)
• Similarity: 388/954 - (40%)
• Gaps: 196/954 - (20%)

  Fly     9 WVLTNSTYLVTKFVRIGIADKNDSPPYFDRFLYETEIDENADLQSTVLTVNAKDHNESTNIRYQI 73
            |:|.....|....|:.|:|:.......|.:..|...:.:|.:....:..|..........|::..
 Frog     7 WLLGAVVLLALLQVQGGLAEWTQCQMGFSKERYSFSVPKNLETDKALGRVIFNSCEGPVRIQFAS 71

  Fly    74 TGGNIGNAFAVQNTTGVIYVASPLDYETRPRYELRLEATRNRKNNYTTVVI-------NVRDVND 131
            ...|    |.: :..|.:||.:|...:.. |...|:.|..|:.:.|:|.|.       :.:|::.
 Frog    72 KDPN----FEI-HKDGTVYVKNPTKMKDN-RKTFRVLAWENQGHVYSTSVTLKGEGHHHKQDISS 130

  Fly   132 ---------------------NPPVFDRQTYRTQITEEDDRN-LPKRILQVTATDGDVDRPINIV 174
                                 .||:         :|.|:::. .|||::|:.:::.   :.|.:.
 Frog   131 VKHSHHPKSETGLKRQKRDWVIPPI---------VTSENEKGPFPKRLVQIKSSNA---KEIKVF 183

  Fly   175 YFLTGQGIDPDNPANSKFDINRTTGDIFVLKPLDRDQPNGRPQWRFTVF--AQDEGGEGLVGYAD 237
            |.:||||  .|.|....|.|.|..|.:.|.:||||:..:.     :|:|  |....|:.:....:
 Frog   184 YSITGQG--ADTPPEGVFTIGREDGWLNVTRPLDREAIDS-----YTLFSHAVSVNGQNVEDPME 241

  Fly   238 IQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEE 302
            ||:.::|.|||.|.|.|.::.|.|.|....|:.|||:||.|.||..:..|..:.||| .|...:|
 Frog   242 IQIKVQDQNDNDPVFTQEVFEGYVPEGSKPGTPVMTVSATDADDAIDMYNGVITYSI-LNQDPKE 305

  Fly   303 TGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGG-GLKGTGTAS--IRVKDLNDMPPQF 364
            ....:|.|:.::|||......||||:.|.|::.:.|.||. |...|.||.  |.|.|.||.||.|
 Frog   306 PNNQMFTIDSQSGLISVVTTGLDREKIPVYTLTIQAADGEFGKDRTTTAKAVIIVTDTNDNPPVF 370

  Fly   365 TKDEWVTEVDETNGTYIPETPILTVTVQDEDETNTFQ--YKVVPNSGFGADKFAMVRNGDGTGSL 427
            ...:::.||.|....|  |...||||..|.:.::.:.  ||::  .|..|..|::..:.|..|.|
 Frog   371 NPTQYIAEVPENEVGY--EVARLTVTDADIEGSDAWNAVYKII--KGNEAGFFSIQTDIDNIGLL 431

  Fly   428 KIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVPKFDREHIEV 492
            |.::.||||...|   :...:.|.:|.:    .|.....:.:.|.|.:.|:|: .|.|.....:|
 Frog   432 KTVKGLDYELKKQ---YILSVIVTNKAN----FSVPLQTSTATVTVTVTDVNE-APVFVPVLKDV 488

  Fly   493 SIYEDTKVGTILEQFKATDADQGGHSKVAYKIVR------STNRKRQFAISDRGAVSIQRPLDRE 551
            |:.||...|.::..:.|.|.|:..:.|::|.|..      |.||       |.|.|:....||||
 Frog   489 SVPEDLPSGQVVATYTAQDPDKEQNQKISYFIGNDPAGWVSVNR-------DNGIVTGNGNLDRE 546

  Fly   552 TQ----DRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQDYKPTLPENVSGKKILEVAA 612
            ::    :.:.:.|||.|.|:|:.|.|.||.:.:.|||||.| |....:.:..:...|.::..:..
 Frog   547 SKFVLNNTYKVIILAADSGTPSATGTGTLVLNLIDVNDNGP-FLDPQQNSFCQKDPGFRVFNIID 610

  Fly   613 KDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGD-NENGVAIIS-----SLRPFDREAQK 671
            ||    |..|..|:|                  .|..|: |||..|.::     .|||.......
 Frog   611 KD----LYPNTYPYT------------------VDLTGESNENWTATVTEQSLLELRPKKELDIG 653

  Fly   672 SYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNKMQPGSKS------------------------- 711
            .|.:.|.::||  ..:|..:.|.:||...|.::||...|:
 Frog   654 RYEVLISLRDN--QGLTDVTKLQITICQCNGDQMQCEEKAAQAGGLGISAIVGILGGILALLLLL 716

  Fly   712 --VLVYNYQGQSQDTPIGRVYVNDPDDWDVPDKKYYWEV----QEHQRFK-------LDTDTGIL 763
              :|::..:.:....|:     ..|:| :..|..::::.    :|.|.|.       ||....|:
 Frog   717 LLLLLFVRRKKVVKEPL-----LPPED-ETRDNVFFYDEEGGGEEDQDFDLSQLHRGLDARPDII 775

  Fly   764 TMRAGTRRGRYQLRFKVYDREHGQEDIPANLSVTVRDITA----------------EAVQQAGSM 812
            ...........|.|.:..:.:.....|..||.....|.||                ||...:...
 Frog   776 RNDVVPVLAAPQYRPRPANPDEIGNFIDENLHAADNDPTAPPYDSLLVFDYEGSGSEAASLSSLN 840

  Fly   813 RLSHITDEDF--VRTWNPVKNQVEPSKLERFRNKLAELLYTDRD 854
            ..:...|:|:  :..|.|           || .||||:...|.|
 Frog   841 SSNSDLDQDYSALNNWGP-----------RF-TKLAEMYGGDED 872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CadN2	NP_001036368.2	Cadherin_repeat	41..132	CDD:206637	18/118 (15%)
		Cadherin_repeat	140..248	CDD:206637	31/110 (28%)
		Cadherin_repeat	256..359	CDD:206637	39/105 (37%)
		Cadherin_repeat	379..481	CDD:206637	28/103 (27%)
		Cadherin_repeat	489..586	CDD:206637	34/106 (32%)
		Cadherin_repeat	594..703	CDD:206637	25/114 (22%)
		Cadherin_repeat	724..801	CDD:206637	15/87 (17%)
		EGF_CA	977..1010	CDD:238011
		LamG	1013..1198	CDD:238058
		EGF_2	<1233..1259	CDD:285248
		Laminin_G_2	1293..1428	CDD:280389
		EGF_CA	1497..1535	CDD:238011
		Cadherin_C	1583..1719	CDD:279398
cdh1	XP_002936043.5	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24027
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100