DRSC/TRiP Functional Genomics Resources

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Protein Alignment CadN2 and pcdh2ab9

DIOPT Version :9

Sequence 1:NP_001036368.2 Gene:CadN2 / 35071 FlyBaseID:FBgn0262018 Length:1799 Species:Drosophila melanogaster
Sequence 2:NP_001009596.2 Gene:pcdh2ab9 / 493595 ZFINID:ZDB-GENE-041118-8 Length:940 Species:Danio rerio


Alignment Length:717 Identity:184/717 - (25%)
Similarity:302/717 - (42%) Gaps:140/717 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 IDENADLQSTVLTVNAKDHN----ESTNIRYQITGGNIGNAFAVQNTTGVIYVASPLDYETRPRY 105
            :.|..:..:||..: |||.|    :.||..:|:..|.....|.:.:.||.:::...:|.:.....
Zfish    33 VSEETNPGTTVGNL-AKDLNLNLQDITNRGFQLVSGANKRYFELNSKTGFLHINDRIDRDELCGR 96

  Fly   106 ELR----LEATRNRKNNYTTVVINVRDVNDNPPVFDRQTYRTQITEEDDRNLP-KRILQVTATDG 165
            .|:    |||..|...|.....:::.|:|||.|.|........|:|.   ..| :|....||.|.
Zfish    97 SLKCSFPLEAIVN
APLNVYRFEVSIIDINDNSPTFRSPVKYFNISES---AFPGERFPLPTAFDA 158

  Fly   166 DVDRPINIVYFLTGQGIDPDNPANSKFDINRTTG-------DIFVLKPLDRDQPNGRPQWRFTVF 223
            ||.......|.|:         ||..|.::..:|       ::.:.|.|||::   :|..:.|:.
Zfish   159 DVGSNSVKSYKLS---------ANEHFSLDVQSGGEQSVSAELVLQKALDREK---QPVIKLTLT 211

  Fly   224 AQDEGGEGLVGYADIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNA 288
            |.|.|.....|..:|.||::|:|||.|.|.:.::...|.||...|:||:.:.|   .||:|..|:
Zfish   212 AVDGGKPPRSGTINIIVNIEDVNDN
IPVFSKPLFKTRVVENSPFGTSVIQVHA---SDPDEGPNS 273

  Fly   289 KLIYSIEKNVIEEETGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIR 353
            :::||:...  :.|..|..|.|:||||:| |....:|.|:.....|:|.|.|.|.........:.
Zfish   274 EIVYSLLSQ--DNENNADAFAIDPETGVI-TVKGTVDYEKNAAVEIRVQAKDKGHKPRAAYCKVL 335

  Fly   354 VK--DLNDMPPQFTKDEWVTEV--DETNGTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGADK 414
            |:  |:||..|:.:....|..|  |..|||.:   .::||...|..:....|.|:..:..|....
Zfish   336 VEITDINDN
TPEISVTSLVNTVKEDAANGTVV---SMITVLDNDAGKNGEIQLKIRDSLPFKVQN 397

  Fly   415 -----FAMVRNGDGTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVK 474
                 :.::.||.          ||.|   .:|.:...|...|:|.. |..|.      |.:.|.
Zfish   398 SYKNYYTLIVNGH----------LDRE---TASEYNVTISAADEGTP-PLSST------SVIAVH 442

  Fly   475 LRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDR 539
            :.|:|||.|:|....|.|.:.|::::|.:|....|.|.|.|.::::.|.::.|         |..
Zfish   443 VSDVNDN
APRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLES---------SKS 498

  Fly   540 GAVSIQRPLDRETQDRHHIQ-------------ILAIDDGSPARTATATLTVIVKDVNDNAPTFA 591
            |.|:....::.:|.|.|.:|             :.|.|.|.|..::..|:.|.|.|.|||:|...
Zfish   499 GPVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAIL 563

  Fly   592 QDYK---PTLPENV-----SGKKILEVAAKDPD-----------DRLRGNGGPFTFRLDPLASDE 637
            ..|.   ....||:     :|..:.::.|.|.|           ...:||.   .||:. .:|.|
Zfish   564 APYSELGSVNTENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNN---LFRIG-TSSGE 624

  Fly   638 IKAGFKVEYDRRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTI----G 698
            |:.     ..|..||:                .|::.:.|.:.|||.|:::.|.::...:    |
Zfish   625 IRT-----KRRMSDND----------------LKTHPLVILVCDNGEPSLSATVSIDAVVVESGG 668

  Fly   699 DV 700
            ||
Zfish   669 DV 670

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CadN2NP_001036368.2 Cadherin_repeat 41..132 CDD:206637 23/94 (24%)
Cadherin_repeat 140..248 CDD:206637 30/115 (26%)
Cadherin_repeat 256..359 CDD:206637 32/104 (31%)
Cadherin_repeat 379..481 CDD:206637 22/106 (21%)
Cadherin_repeat 489..586 CDD:206637 27/109 (25%)
Cadherin_repeat 594..703 CDD:206637 27/130 (21%)
Cadherin_repeat 724..801 CDD:206637
EGF_CA 977..1010 CDD:238011
LamG 1013..1198 CDD:238058
EGF_2 <1233..1259 CDD:285248
Laminin_G_2 1293..1428 CDD:280389
EGF_CA 1497..1535 CDD:238011
Cadherin_C 1583..1719 CDD:279398
pcdh2ab9NP_001009596.2 Cadherin_2 29..109 CDD:311943 19/76 (25%)
Cadherin_repeat 137..236 CDD:206637 30/113 (27%)
Cadherin_repeat 245..344 CDD:206637 33/104 (32%)
Cadherin_repeat 356..449 CDD:206637 26/115 (23%)
Cadherin_repeat 457..558 CDD:206637 27/109 (25%)
Cadherin_repeat 576..659 CDD:206637 22/107 (21%)
Cadherin_C_2 686..758 CDD:318652
Cadherin_tail 795..912 CDD:318236
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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