Protein Alignment CadN2 and cdh16

DIOPT Version :10

• Sequence 1: NP_609855.3
• Gene: CadN2 / 35071
• FlyBaseID: FBgn0262018
• Length: 1799
• Species: Drosophila melanogaster
• Sequence 2: XP_073763310.1
• Gene: cdh16 / 101886380
• ZFINID: ZDB-GENE-140106-140
• Length: 819
• Species: Danio rerio
• Alignment Length: 833
• Identity: 186/833 - (22%)
• Similarity: 316/833 - (37%)
• Gaps: 238/833 - (28%)

  Fly    10 VLTNSTYLVTKFVRIGIADKNDS--PPYFDRFLYETEIDENADLQSTV--LTVNAKDHNESTNIR 70
            :|:.|.:|     :||:.:..|.  |.|..:.         .||..|.  ||||..|.
Zfish    19 LLSESAHL-----KIGVPENYDGIFPWYLTKL---------PDLPLTYSDLTVNGDDE------- 62

  Fly    71 YQITGGNIGNAFAVQNTTGVIYVASPLDYETRPRYELRLEATRNRKNNYTTVVINVRDVNDNPPV 135
                     ..|.|:  :|.:|...|||.|.:|.|.|::..|::......||.:.|.|.|||.||
Zfish    63 ---------GIFGVE--SGFLYALKPLDREKQPSYSLQVSFTKSMHTQSFTVEVCVIDKNDNVPV 116

  Fly   136 FDRQTYR---------------TQITEEDDRN-------------LPK----RILQVTATDGDVD 168
            |..::.|               .:..:.||||             :|:    .:..:.:..|:|.
Zfish   117 FLEESMRGSVQLGLLKGIPFMQVEALDRDDRNTAHADLRFSLLDQIPRIPASHMFSIDSITGEVS 181

  Fly   169 RPINIVYFLTGQG---IDPD---------------NPANS------------------------- 190
                    ||..|   :||:               ..||:
Zfish   182 --------LTEDGASTLDPEMCGRYKLSVMVQDMAGKANAFFSTGTVLVEVTGNAWASPDPVRLQ 238

  Fly   191 --------------------------------KFDINRTTGDIFVLKPLDRDQPNGRPQWRFTVF 223
                                            .|.||| .|.|::..||||:.   :.|:...:.
Zfish   239 ENLPGPYPIPISQVKWSGSPVEYSLEGEFPEMLFTINR-EGIIYLNAPLDRET---QDQFHIDIV 299

  Fly   224 AQDEGGEGLVGYADIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNA 288
            .:...|..:....:::|.:.|.|||.|.|||..|...|.|..|.|:.::|:.|.|.||| ::.|.
Zfish   300 VERPDGREIAKPVELRVMVGDANDNRPTFPQMQYHTVVKELATKGTEILTVQAADNDDP-KTDNV 363

  Fly   289 KLIYSIEKNVIEEETGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIR 353
            ::.|.:...:  .||...:|.::.::|:|......:: ...|.|::.:.|.|..||..:.|..::
Zfish   364 RIFYRLVGQM--PETPRNLFRVDRDSGVITVQADSME-GTAPQYTLTITAEDAKGLNSSCTVIVK 425

  Fly   354 VKDLNDMPPQFTKDEW----VTEVDETNGTYIPETPILTVTVQDEDE--TNTFQYKVVPNSGFGA 412
            |.|.|:.||.|:..|:    :.| |.:.|     |.:..|:..|.||  .:::|......||...
Zfish   426 VLDENNNPPIFSHLEYGPFHLAE-DSSVG-----TTVTVVSAWDADEWGGDSWQVDYRLESGNEE 484

  Fly   413 DKFAMVRNGDGTGSLKII--QPLDYEDPLQSSGFRFRIQVND-----KGDDGPGGSDKYHVAYSW 470
            :.|.:: |...|....:|  :.||:|   :.:.:...:...:     :|..||..:       :.
Zfish   485 EVFTLL-NDRQTNEAALILDKVLDFE---RENEYILVLSAQNPVALVRGRYGPAST-------AT 538

  Fly   471 VVVKLRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFA 535
            |.:.:.|||:. |...:.|.||::.|..:.|.::...:..|.|.   ..:.|.:...|  ||.|:
Zfish   539 VTIFIDDINEG-PVLSQSHYEVTVREGEEPGRVIATIRGYDPDS---HPIRYSLRGDT--KRYFS 597

  Fly   536 ISD-RGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQDYK---- 595
            |.. .|.:...:.||||....:.::::|.|..:.:.:|:..:||.:.|||||:|....||.
Zfish   598 IGKYSGELKTVQALDREENHTYTMEVVAEDGRNSSLSASTLVTVHILDVNDNSPVLVGDYSWKYL 662

  Fly   596 --PTLPENVSGKKILEVAAKDPDDRLRGNGGPF----------TFRLDPLASDEIKAGFKVEYDR 648
              |...:     :.|.:|::|.|....|....|          |::|.|:..........|.|
Zfish   663 CTPRWED-----QALVLASRDSDGPQHGGRLNFSLRSDATVRRTWKLTPINDTHTNLSLNVPY-- 720

  Fly   649 RGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVN 701
                         |.|      :.|.:|..|.|:.:|..:....|.||:...|
Zfish   721 -------------LPP------EVYIVPFTISDSSSPPRSTFINLPVTVCPCN 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CadN2	NP_609855.3	Cadherin_repeat	41..132	CDD:206637	25/92 (27%)
		Cadherin_repeat	140..248	CDD:206637	30/214 (14%)
		Cadherin_repeat	256..359	CDD:206637	27/102 (26%)
		CA	388..483	CDD:214520	21/103 (20%)
		Cadherin_repeat	489..586	CDD:206637	26/97 (27%)
		Cadherin_repeat	594..703	CDD:206637	24/124 (19%)
		EGF_CA	977..1010	CDD:238011
		LamG	1013..1198	CDD:238058
		EGF_2	1233..1259	CDD:400365
		LamG	1265..1426	CDD:238058
		EGF_CA	1497..1535	CDD:238011
		CADH_Y-type_LIR	1662..1719	CDD:460041
cdh16	XP_073763310.1	None