Protein Alignment CadN2 and LOC101886358

DIOPT Version :10

• Sequence 1: NP_609855.3
• Gene: CadN2 / 35071
• FlyBaseID: FBgn0262018
• Length: 1799
• Species: Drosophila melanogaster
• Sequence 2: XP_021336085.2
• Gene: LOC101886358 / 101886358
• -ID: -
• Length: 816
• Species: Danio rerio
• Alignment Length: 821
• Identity: 201/821 - (24%)
• Similarity: 343/821 - (41%)
• Gaps: 190/821 - (23%)

  Fly   164 DGDVDRPINIVYFLTGQGIDPDNPANSKFDINRTTGDIFVLKPLDRDQPNGRPQWRFTVFAQD-- 226
            ||.|.      |.|:|:|      |.|.|.||..||||...|.|||::.:     .:.:.||.
Zfish    91 DGSVR------YILSGEG------AGSIFIINEVTGDIHATKSLDREKKS-----HYVLHAQAID 138

  Fly   227 -EGGEGLVGYADIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKL 290
             ...:.|...::..:.::|||||||:||.|.:..:|.|....|:||..::|.|.|||....:|::
Zfish   139 INTNKPLEPESEFIIKVQDINDNAPKFPDGPFVTSVPEMSELGTSVFQVTATDADDPTYGNSARV 203

  Fly   291 IYSIEKNVIEEETGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMD----GGGLKGTGTAS 351
            :||:..       |.|.|.::|:||:|:||:..:|||....||:.:.|.|    .|||.|:.|.:
Zfish   204 VYSVLH-------GQPYFSVDPKTGIIRTALADMDREAREHYSVVIQAKDMAGQVGGLSGSTTVN 261

  Fly   352 IRVKDLNDMPPQFTKDEWVTEVDETNGTYIPET-----PILTVTVQDEDETNTFQYKVVPNSGFG 411
            |.:.|:||.||:|.:..:        ..::||:     |:..:...|||.....:.|....:..|
Zfish   262 ITLTDVNDNPPKFPQKNY--------QVFVPESAQVGKPVGKIKANDEDIGINAEIKYSILNPEG 318

  Fly   412 ADKFAMVRNGD-GTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHV--AYSW--- 470
            |..|::..:.| ..|.:.:.:||:||...|     :.:.::         ::..||  .||:
Zfish   319 AAVFSISTDKDTREGVITLRKPLNYEKKKQ-----YSLHIS---------AENTHVDPRYSYLGS 369

  Fly   471 ------VVVKLRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTN 529
                  :.:.:.|: |..|.|..::..:.:||:.:|||.:....|.|.| ..:|.|.|.|.|..:
Zfish   370 FKDDATLKITVGDV-DEPPLFSMDYYIMEVYENARVGTEVGAVTARDPD-SKNSPVRYFIERRED 432

  Fly   530 RKRQFAI-SDRGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQD 593
            ::..|.| |..|.:...:.||||....|:|.::|.::.:|:..:...:||.|.|||||.|....:
Zfish   433 KEVYFDIESISGVIRTTQLLDREDTPWHNITVMATEEDNPSLQSHVPVTVQVLDVNDNPPKINTE 497

  Fly   594 YKPTLPENV-SGKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENGVA 657
            .:..:.|.. :|..|..:.|.|.||...|.|..|:|.    ........|.::     |||:..|
Zfish   498 DEIIICEGTRAGHVIQTITAVDKDDFANGKGFSFSFP----GGVSANPNFTIK-----DNEDSTA 553

  Fly   658 IISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNKMQPGSKSVLVYNYQGQSQ 722
            .|::.|.|.|..|:.|.:.:.:.|:|.|.::.|.|||:.:     ...|.|::
Zfish   554 SITARRRFHRLTQELYELAVVVWDDGEPVLSSTGTLTLRV-----CSCQRGTR------------ 601

  Fly   723 DTPIGRVYVNDPDDWDVPDKKYYWEVQEHQRF--KLDTDTGIL------------------TMRA 767
                                   .::.:.:.|  .....||.|                  |:|.
Zfish   602 -----------------------LKICQSEAFLSSAGLSTGALIAILLCILILLAIVILFITLRR 643

  Fly   768 GTRR----GRYQLRFKV--YDRE-HGQEDIPANLSVTVRDITAEAVQQAGSMRLSHITDEDFVRT 825
            ..:.    ....:|..|  ||.| .|:||..|...:.:|:..|     |..::.......:.:|.
Zfish   644 SKKEPLIISEEDIRENVVTYDDEGGGEEDTEAFDIIALRNPAA-----AEELKFRRDVQPECIRP 703

  Fly   826 WN---PVKNQVEPSKL---------ERFRNKLAELLYTDRDN----VDVFSVQLKEGSPYPLTDV 874
            |:   |:::::.||.|         |..:.:::|   .|:|.    .|.......||...|...:
Zfish   704 WSSRRPIRSRLSPSSLDIDEETDVGEFIKQRVSE---ADQDTSVPPYDSLQTYAYEGQGSPAGSI 765

  Fly   875 HFAARSATQQ-----------PYFKAVRLNGVVQMHREEIE 904
            ..........           |.|:.     :.:::.|:||
Zfish   766 SSLGSPGAHSDLDYNSLDDWGPKFEK-----IAELYGEDIE 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CadN2	NP_609855.3	Cadherin_repeat	41..132	CDD:206637
		Cadherin_repeat	140..248	CDD:206637	26/86 (30%)
		Cadherin_repeat	256..359	CDD:206637	36/106 (34%)
		CA	388..483	CDD:214520	20/106 (19%)
		Cadherin_repeat	489..586	CDD:206637	31/97 (32%)
		Cadherin_repeat	594..703	CDD:206637	29/109 (27%)
		EGF_CA	977..1010	CDD:238011
		LamG	1013..1198	CDD:238058
		EGF_2	1233..1259	CDD:400365
		LamG	1265..1426	CDD:238058
		EGF_CA	1497..1535	CDD:238011
		CADH_Y-type_LIR	1662..1719	CDD:460041
LOC101886358	XP_021336085.2	None