DRSC/TRiP Functional Genomics Resources

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Protein Alignment CadN2 and cdh10

DIOPT Version :10

Sequence 1:NP_609855.3 Gene:CadN2 / 35071 FlyBaseID:FBgn0262018 Length:1799 Species:Drosophila melanogaster
Sequence 2:XP_002935630.3 Gene:cdh10 / 100496218 XenbaseID:XB-GENE-1012079 Length:787 Species:Xenopus tropicalis


Alignment Length:797 Identity:205/797 - (25%)
Similarity:334/797 - (41%) Gaps:196/797 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   166 DVDR-PINIVYFLTGQGIDPDNPANSKFDINRTTGDIFVLKPLDRDQPNGRPQWRFTVFAQ---D 226
            |:|: ..::.|.|:|.|      |.:.|.|:..||||...:.:||::     :..:|:.||   .
 Frog    80 DLDKGDESLKYILSGDG------AGTLFVIDEKTGDIHATRRIDREE-----KAFYTLRAQAVNR 133

  Fly   227 EGGEGLVGYADIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLI 291
            ..|..:...::..:.:.|||||.|.|.:.:|..:|.|....|:.|:.::|.|.|||:...:||:|
 Frog   134 RTGRPVEPESEFVIKIHDINDNEPTFLEEVYTASVPEMSDVGTYVVQVTAADADDPSYGNSAKVI 198

  Fly   292 YSIEKNVIEEETGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMD----GGGLKGTGTASI 352
            |||.:       |.|.|.:|||||:|:||:..::||....|.:.:.|.|    .|||.||.|.:|
 Frog   199 YSILQ-------GQPYFSVEPETGIIRTALPNMNRENREHYQVVIQAKDMGGQMGGLSGTTTVNI 256

  Fly   353 RVKDLNDMPPQFTKDEWVTEVDETNGTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGADKFAM 417
            .:.|:||.||:|:::.:...|        |||..:..||.....|:.       :.|..|:....
 Frog   257 TLSDVNDNPPRFSQNSYHISV--------PETATVGSTVGRIKATDA-------DIGKNAEVEYR 306

  Fly   418 VRNGDGT-------------GSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAY- 468
            :.:||.|             |.:.:.:.||||   ....:..:::..:...|.       |..| 
 Frog   307 ILDGDETAVFNIFTEKSTQDGVITVRKRLDYE---SKRLYTLKVEAMNTHVDP-------HFYYL 361

  Fly   469 ------SWVVVKLRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRS 527
                  ..|.:.:.|: |..|.|.|......::||.::|||:....|.|.| ...|.|.:.:.|.
 Frog   362 GPFKDTCTVKISVEDV-DEPPVFSRPSYMFKVHEDIELGTIIGTVMARDPD-AISSPVRFSLDRH 424

  Fly   528 TNRKRQFAI-SDRGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFA 591
            |:..|.|.| |..|::...:|||||....|::.::|.:..:|.:...||:.:::.|:|||||.||
 Frog   425 TDLDRIFHIYSGNGSIYTAKPLDREISQWHNLTVIATEINNPKQATRATVFILILDINDNAPEFA 489

  Fly   592 QDYKPTLPENV-SGKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENG 655
            ..|...:.||. :|:.|..::|.|.|:  ...|..|.|   .|||  :...|.|:     |||:.
 Frog   490 MFYDTFVCENARAGQLIQTISAVDKDE--PPGGQKFFF---SLAS--VNPNFTVQ-----DNEDN 542

  Fly   656 VA-IISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTI---------------------- 697
            .| |::....|:|....:|.:|:.|.||..|..:.|.|||:.:                      
 Frog   543 TARILTRRNGFNRHEINTYLLPVVISDNDYPIQSSTGTLTIKVCTCDSQGNMQSCNAEALLLPAG 607

  Fly   698 ---------------------------------------GDVNDNKMQPGSKSVLVYNYQG---- 719
                                                   .|:.||        ::.||.:|    
 Frog   608 LSTGALIAILLCIIILLLIVVLFAALKRQRKKEPLVLSKEDIRDN--------IVSYNDEGGGEE 664

  Fly   720 QSQDTPIGRVYVNDPDDWDVPDKKYYWEVQEHQRFKLDTDTGILTMRAGTRRGRYQLRFKVYDR- 783
            .:|...||.  :.:|...|  |||        ||..:..::.:|..|.........:|..:..| 
 Frog   665 DTQAFDIGT--LRNPGSID--DKK--------QRRDIIPESLLLPRRTAAVPDNTDVRDFINQRL 717

  Fly   784 -EHGQE------DIPANLSVTVRDITAEAVQQAGSMRLSHITDEDFVRTWNPVKNQVEPSKLERF 841
             ||..:      |..|..:....|..||::....|.......:.|:::.|.|           ||
 Frog   718 KEHDSDPTAPPYDSLATYAYEGNDSIAESLSSLDSSTTDGDQNYDYLKEWGP-----------RF 771

  Fly   842 RNKLAELL---YTDRDN 855
             |||||:.   .:|:|:
 Frog   772 -NKLAEMYGSGESDKDS 787

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CadN2NP_609855.3 Cadherin_repeat 41..132 CDD:206637
Cadherin_repeat 140..248 CDD:206637 22/85 (26%)
Cadherin_repeat 256..359 CDD:206637 40/106 (38%)
CA 388..483 CDD:214520 19/114 (17%)
Cadherin_repeat 489..586 CDD:206637 29/97 (30%)
Cadherin_repeat 594..703 CDD:206637 34/171 (20%)
EGF_CA 977..1010 CDD:238011
LamG 1013..1198 CDD:238058
EGF_2 1233..1259 CDD:400365
LamG 1265..1426 CDD:238058
EGF_CA 1497..1535 CDD:238011
CADH_Y-type_LIR 1662..1719 CDD:460041
cdh10XP_002935630.3 CA 79..157 CDD:214520 24/87 (28%)
Cadherin_repeat 163..264 CDD:206637 41/107 (38%)
Cadherin_repeat 272..379 CDD:206637 22/132 (17%)
Cadherin_repeat 387..484 CDD:206637 29/97 (30%)
Cadherin 492..586 CDD:394985 33/105 (31%)
CADH_Y-type_LIR 720..779 CDD:460041 17/70 (24%)
Blue background indicates that the domain is not in the aligned region.

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