Protein Alignment CadN2 and cdh17

DIOPT Version :10

• Sequence 1: NP_609855.3
• Gene: CadN2 / 35071
• FlyBaseID: FBgn0262018
• Length: 1799
• Species: Drosophila melanogaster
• Sequence 2: NP_001135580.1
• Gene: cdh17 / 100216129
• XenbaseID: XB-GENE-868449
• Length: 830
• Species: Xenopus tropicalis
• Alignment Length: 744
• Identity: 188/744 - (25%)
• Similarity: 297/744 - (39%)
• Gaps: 165/744 - (22%)

  Fly    22 VRIGIADKNDSPPYFDRFLYETEIDENADLQSTVLTVNAKDHNE--------STNIRYQITGGNI 78
            :.|.:.|.||:.|.|::..|:.|:.|........:.|.|.|.::        |.:|..||...|
 Frog   111 ITIIVEDINDNRPVFNQSEYKGEVREKYRPGRPFVRVYATDADDPSTPNAQLSYSILQQIPDSN- 174

  Fly    79 GNAFAVQNTTGVIYV---ASPLDYETRPRYELRLEATRNRKNNYTTVVINVRDVNDN-----PPV 135
            ...|.:.|.||.|.|   .|.| ......|.|.::.:.:.:::::..|:....:.:|     ||:
 Frog   175 PKYFQINNITGDISVTWNGSQL-LTVGKDYNLIVQVSDSAEHHFSNTVMVKITIKENIWVAPPPI 238

  Fly   136 FDRQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQGIDPDNPANSKFDINRTTGD 200
                    .|.|......|.:|.||...|.:.      :|.|..:...|..|    |.|: ..||
 Frog   239 --------TINENSTEPHPMKITQVRWNDDEA------LYELHQRDRYPRFP----FSID-AIGD 284

  Fly   201 IFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADIQVNLKDINDNAPQFPQGIYFGNVTENG 265
            |:|.:||||::   |.|:.|...|:...|........|:||::|||||.|..|..|....|.||.
 Frog   285 IYVSEPLDREE---RSQYIFYAIAKSRNGLFASSPLTIEVNVEDINDNPPVCPALITIFEVQENE 346

  Fly   266 TAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAP---IFEIEPETGLIKTAVCCLDRE 327
            ..||:|....|.|.|:.. |.|..|:|    .::|:....|   :|.:...||.::.....|:.|
 Frog   347 GIGSTVGEFQASDADEEG-SFNTLLVY----RILEQIPTIPFNNVFSLNEFTGQLQLQRSTLNVE 406

  Fly   328 RTPDYSIQVVAMDGG---GLKGTGTASIRVKDLNDMPPQFTKDEW--VTEVDETNGTYIPETPIL 387
            ...:|.::|...|.|   .||...|..:.|.|:||..|.|.|.|:  ||..::|.    .:|.::
 Frog   407 EVDEYILKVEVSDSGRPTSLKTICTIQVNVIDINDNIPIFEKSEYGNVTIKEDTQ----LQTVVM 467

  Fly   388 TVTVQDEDETNTFQYKVVPNSGFGADKFAMVRNGD-------------GTGSLKIIQPLDYE--- 436
            .:...|:|:.||....::..          ::.||             ..|.:||.:|||:|
 Frog   468 EIQATDDDQPNTGSSLIIYE----------IKEGDPHKMFIIETERETNRGYVKIAKPLDFETMQ 522

  Fly   437 -----------DPL-------QSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVP 483
                       :||       .||..||.:.|.|.                          |..|
 Frog   523 EHRLVIHATNPEPLVAGVAYNDSSITRFTVFVMDV--------------------------DEKP 561

  Fly   484 KFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDR--GAVSIQR 546
            .|:....:..:.||..|||.:....|.|.:  |.| :.:.:...|   |.:...|.  |.:..:.
 Frog   562 YFNETLYQKQVKEDVPVGTKIATITAIDPE--GDS-IRFSLQGDT---RNWLRIDEYTGEMFTKA 620

  Fly   547 PLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQDY-------KPTLPENVSG 604
            .|||||:..:.:.::|.:..:|..:|:....:.::|||||.|..|:.|       ..|.||:|
 Frog   621 LLDRETESHYRVTVIASEKTNPRMSASVLFNLFLEDVNDNPPRLAKSYFGTYFCHPVTKPESV-- 683

  Fly   605 KKILEVAAKDPD-DRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENGVAIISSLRPFDRE 668
              ::|  |.||| .||.    ||.|.|.|...|.:....         |.....:..:...|:
 Frog   684 --VIE--ATDPDAQRLT----PFKFSLTPDEKDWVIVRL---------NRTHAKLTMAHSQFE-- 729

  Fly   669 AQKSYAIPIEIKDNGAPAMTGTSTLTVTI 697
             .|:|.|.:.|.|.|.|.:.....:.|:|
 Frog   730 -MKNYDITVIINDQGIPPLESEVHIPVSI 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CadN2	NP_609855.3	Cadherin_repeat	41..132	CDD:206637	22/101 (22%)
		Cadherin_repeat	140..248	CDD:206637	32/107 (30%)
		Cadherin_repeat	256..359	CDD:206637	30/108 (28%)
		CA	388..483	CDD:214520	22/128 (17%)
		Cadherin_repeat	489..586	CDD:206637	24/98 (24%)
		Cadherin_repeat	594..703	CDD:206637	29/112 (26%)
		EGF_CA	977..1010	CDD:238011
		LamG	1013..1198	CDD:238058
		EGF_2	1233..1259	CDD:400365
		LamG	1265..1426	CDD:238058
		EGF_CA	1497..1535	CDD:238011
		CADH_Y-type_LIR	1662..1719	CDD:460041
cdh17	NP_001135580.1	CA	59..123	CDD:214520	4/11 (36%)
		Cadherin_repeat	129..228	CDD:206637	22/100 (22%)
		Cadherin_repeat	238..329	CDD:206637	32/112 (29%)
		Cadherin_repeat	340..442	CDD:206637	30/106 (28%)
		Cadherin_repeat	453..559	CDD:206637	25/145 (17%)
		Cadherin_repeat	568..660	CDD:206637	24/97 (25%)