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Protein Alignment CadN and Pcdhgb2

DIOPT Version :9

Sequence 1:	NP_001027277.1	Gene:	CadN / 35070	FlyBaseID:	FBgn0015609	Length:	3101	Species:	Drosophila melanogaster
Sequence 2:	NP_291053.1	Gene:	Pcdhgb2 / 93700	MGIID:	1935170	Length:	928	Species:	Mus musculus

Alignment Length:	767	Identity:	194/767 - (25%)
Similarity:	335/767 - (43%)	Gaps:	146/767 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   624 NGKVDDRRFQSTPEE--RLSIVGGKRAPQFYMPSYEAEIPENQKKDSDIISIKAKSFADREIRYT 686
            :|.:.|:...|.|||  :.||||                  |..:|   :.:..::...|::|.:
Mouse    25 HGALADQIRYSIPEELAKNSIVG------------------NLARD---LGLSVQNLPTRKLRVS 68

  Fly   687 LKAQGQGAGTFNIGPTSGIVKLAKELDFEDL--RQPH-VYSLIVTATEDSGGFSTSVDLTIRVTD 748
            .:..     .|.:.|.||.:.:...:|.|.:  :||. |....:.|.:....|..:|.|    .|
Mouse    69 AEKD-----YFTVNPESGDLLVGDRIDREQVCGKQPQCVLEFDIVAEKPLNIFHVAVIL----QD 124

  Fly   749 VNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGSNA-EIEYLVSDDHFAVDSNGI---- 808
            ||||||.|:..:... |:.|....|.:.....|:|.|:|||: :..||..:::|.|.....
Mouse   125 VNDNAPLFKQSEVDL-NIGESTRPGKAFPLDPALDLDAGSNSLQKYYLTDNEYFEVTEKETPDGR 188

  Fly   809 ----IVNNKQLDADNNNAYYEFIVTAKDKGEPPKSGVATVRVYTKNKNDEEPKFSQQVYTPNVDE 869
                ::..:.||.:.:| :::.::||.|.|:||:||...:|:...:.||..|.|||.|::..:.|
Mouse   189 KYPELILKRFLDREEHN-FHQLVLTAVDGGDPPRSGTTQIRIQVTDINDNPPMFSQDVFSVTLRE 252

  Fly   870 NAGPNTLVTTVVASDKD-GDNVRFGFVGGGTSSGQFVIEDITGVIRLHNKAISL-DKD------- 925
            :..|...|..|.|:|:| |.|...      |.:...|.|.:..:..|..:...: .||
Mouse   253 DVPPGFSVLQVTATDQDEGVNAEI------TYAFHNVDEQVERIFNLDKRTGEITTKDNLDFETA 311

  Fly   926 -KYELNVTAMDDGSCCVNGDQTIHTSTAVVVVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVI 989
             .|.|||.|.|.      ||...|.|   :.|.|.|.||..|.....|.:.| :.|.:|.|:.:.
Mouse   312 KSYTLNVEAKDP------GDLASHCS---IQVKILDENDCVPEVIVTSVFTP-LPEDSPLGTVIA 366

  Fly   990 KVVATDEDKGVNGQVKYSIVQQPNQKGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQG 1054
            .:...|.|.|.||.|...::  .|:.....:..:...::.|::..|||....  .:||:.|.|:|
Mouse   367 LIKTRDRDSGENGDVYCHVL--GNEGFVLKSSSKNYYKLVTDRTLDREAIPE--YNVTIVAADRG 427

  Fly  1055 DPSLEGVCSFTVEITDVNDNPPLFDRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSLTA 1119
            .|.|......|:.|:|||||.|:|.:..|:.:|.::...||:|.:|||||.|..:||.|.||:.|
Mouse   428 KPPLSSNVIITLHISDVNDNAPVFHQASYLVHVAENNPPGTSIAQVSASDPDLGSNGLISYSIIA 492

  Fly  1120 PFNPNDLE------YFEIQAESGWIVLKKPLDGCYPRDRYRLRVSASDKGTPASAADVDVELDVV 1178
                :|||      :..:..:||.:..::..|....|. ::|.:.|.|.|:|..:|:|.:.:.|.
Mouse   493 ----SDLEPRALSSFVSVNQDSGVVFAQRAFDHEQLRS-FQLTLQARDHGSPTLSANVSMRVLVG 552

  Fly  1179 DRNNKPPIWDKSIYGPIH---------IRENVTVGTVVTSVKASSGIEGNPTVFYRLMPGSTAQT 1234
            |||:..|   :.:|..:.         :......|.:||.|.|.....|:
Mouse   553 DRNDNAP---RVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGH--------------- 599

  Fly  1235 NKFHTFYLQQRPDN-----GDTWADIKVNHPL-DYESIKEYNLTIRVENNGAQQLASEATVYIML 1293
            |.:.::::.|..|.     |....:::....| |.:|.:: .|.:.|.:.|...|::.||:::
Mouse   600 NAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSARQ-RLLVAVRDGGQPPLSATATLHL-- 661

  Fly  1294 EDVNDEIPLFTEREQETV--LEGEPIGTKVTQVNAIDKDGTFPNNQVYYYIV 1343
                    :|.:..||.:  |..:|:.:.             |.:::.:|:|
Mouse   662 --------IFADSLQEVLPDLSDDPLPSD-------------PQSELQFYLV 692

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.