Sequence 1: | NP_001027277.1 | Gene: | CadN / 35070 | FlyBaseID: | FBgn0015609 | Length: | 3101 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_003728.1 | Gene: | DCHS1 / 8642 | HGNCID: | 13681 | Length: | 3298 | Species: | Homo sapiens |
Alignment Length: | 3520 | Identity: | 780/3520 - (22%) |
---|---|---|---|
Similarity: | 1258/3520 - (35%) | Gaps: | 1028/3520 - (29%) |
- Green bases have known domain annotations that are detailed below.
Fly 56 GSP-------GDVEKSSLSHHSEMSLVLPHDTYPGFSIKKFKTHPVKINGSSHSGAAAYHMLDT- 112
Fly 113 -----------DYSKYFTVLEDGVV-------MTTADISPLVNRPVQLVVVEQT-----PNATNT 154
Fly 155 HN--LQL-----FVMHRNDML----RFSGSLLDASG--------EVRENQPAGTRVRGVPLMQAF 200
Fly 201 SGSILDEELATPKKVRYTIIDGNVDDA-FALQERKANKNIQISAKSLVINGDDESGVWLV-TNRP 263
Fly 264 LDREERAHYDLSVEASDVDGLD-RTVSKIQITVLDENDNRPIFKSLDYK------FAIAGQ---- 317
Fly 318 ---KSASMESNSSVTYQRFAIMGKVEATDADGDKIAYRLKSPSNVVIIVPQTGEIMLAGEPTSNE 379
Fly 380 LLIEVIAHDLRYPSLVSAKPAKVLLEFLAAEPVSFIMQHLEHDDINNHSHHREK----RRVTRAV 440
Fly 441 RP-TKRIEFTEADGD----------------TEGKSVFQLEKETDKETFKIRDDNPWVTVETNGA 488
Fly 489 VRVKKKWDYEELGPEKTIDFWVIITNMGHNAGIKYTDNQRVIILVKDVNDEPPYFINRPLPMQAV 553
Fly 554 VQLNAPPNTPVFTLQARDPD--TDHNIHYFIVRDRTGGRFEVDERSGVVRT------RGTDLFQL 610
Fly 611 DMEYVLYVKAEDQNGKVDDRRFQSTPEER--LSIVGGKRAPQ-FYMPSYEAEIPENQKKDSDIIS 672
Fly 673 IKAKSFADREIRYTLK-AQGQGAGTFNIGPTSGIVKLAKELDFEDLRQPHVYSLIVTATEDSG-- 734
Fly 735 -GFSTSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPL-------GTSILRVKAMDSDSGSNAE 791
Fly 792 IEYLV---SDDHFAVD-SNGIIVNNKQLDADNNNAYYEFIVTAKDKGEPPKSGVATVRVYTKNKN 852
Fly 853 DE--EPKFSQQVYTPNVDENAGPNTLVTTVVASDKDGDNVRFGFVGGGTSSGQFVIEDITGVIRL 915
Fly 916 HNKAISLDKDK---YELNVTAMDDGSCCVNGDQTIHTSTAVVVVFITDVNDNKPVFKDCSTYYPK 977
Fly 978 VEEGAPNGSPVIKVVATDEDKGVNGQVKYSIVQQPNQKGTKFTVDEETGEVSTNKVFDREGDDGK 1042
Fly 1043 FVSVTVKATDQGDPSLEGVCSFTVEITDVNDNPPLFDRQKYVE------NVKQDASIGTNILRVS 1101
Fly 1102 ASDEDADNNGAIVYSLTAPFNPNDLEYFEIQAESGWIVLKKPLDGCYPRDRYRLRVSASDKGTPA 1166
Fly 1167 SAADVDVELDVVD--RNNKPP--IWDKSIYGPIHIRENVTV------GTVVTSVKASSGIEGNPT 1221
Fly 1222 VFYRLMPGSTAQTNKFHTFYLQQRPDNGDTWADIKVNHPLDYESIKEYN-LTIRVENNGAQQLAS 1285
Fly 1286 EATVYIMLEDVNDEIPLFTEREQETVLEGEP-IGTKVTQVNAIDKDGTFPNNQVYYYIVDSPRNE 1349
Fly 1350 GK-EFFEINLQSGEIFTKTVFDREKKGAYALEVEARDGAPSARP-NSNGPNSVTKFIRIGIADKN 1412
Fly 1413 DNPPYFDKSLYEAEVDENEDIQHTVLTVTAKDHD--ESSRIRYEITSGNIGGAFAVKNMTGAIYV 1475
Fly 1476 AGALDYETRRRYELRLAASD--NLKENYTTVI-IHVKDVNDNPPVFERPTYRTQITEED------ 1531
Fly 1532 --------------------------------------------------------DRNLPKRVL 1540
Fly 1541 QVT---ATDGDKDR------------------PQNIVYFLTGQGIDPDNPANSK----------- 1573
Fly 1574 --FDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDINDNAPIFPQ 1636
Fly 1637 GVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSPIFEIEPDTGVIKT 1701
Fly 1702 AVCCLDRERTPDYSIQVVAMDG---GGLKGTGTASIRVKDINDMPPQFTKDEWFTEVDETDGT-A 1762
Fly 1763 LPEMPILTVTVHDED--ETNKFQYKVIDN--SGYGADKFTMVRNNDGTGSLKIVQ-PLDYEDQLQ 1822
Fly 1823 SNGFRFR---IQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPHFERANVEVSVFEDTKVGTEL 1884
Fly 1885 EKFKATDPDQGGKSKVSYSIDRSSDRQRQFAIN-QNGSVTIQ--RSLDREVVPRHQVKILAIDDG 1946
Fly 1947 SPPKTATATLTVIVQDINDNAPKFLK-DYRPVLPEHVPPRKVVE--ILATDDDDRSKSNGPPFQF 2008
Fly 2009 RLDPSADDIIRASFKVEQDQKGANGDGMAVISSLRSFDREQQKEYMIPIVIKDHGSPAMTGTSTL 2073
Fly 2074 TVIIGDVNDNK---MQPG----SKDIFVYNYQGQSPDTPIGRVYVYDLDD----WDLPDKKFYWE 2127
Fly 2128 AMEHPR--FKLDEDSGMVTMRAGTRE----GRYHLRFKVYDRKHTQTDIPANVTVTVREIPHEAV 2186
Fly 2187 VNSGSVRLSGISDEDFIRVWNYRTQSMSRSKMDRFRDKLADLLNTERENVDIFSVQLKRKHPPLT 2251
Fly 2252 DVRFSAHGSPYYKPVRLNGIVLMHREEIEKDVGINITMVGIDECLYENQMCEGSCTNSLEISPLP 2316
Fly 2317 YMVNANKTALVGVRVDTIADCTCGARNFTKPESCRTTPCHNGGRCVDT--RFGPHCSCPVGYTGP 2379
Fly 2380 RCQQTTRSFRGNGWAWYPPLEMCDESHLSLEFITRKPDGLIIYNGPI---VPPERDETLISDFIA 2441
Fly 2442 LELERGYPRLLIDFGSGTLELRVKTKKTLDDGEWHRIDLFWDTESIRMVVDFCKSAEIAEMEDGT 2506
Fly 2507 PP--------------EFDDM-------SCQARGQIPPFNEY---------LNVNAPLQVGGLYR 2541
Fly 2542 EQFDQ------SLYFWHYMPTAKGFDGCIRNLVHN---SKLYD---------LAHPGLSRNSVAG 2588
Fly 2589 CPQTEEVCAQTETTARCWEHGNCVGSLSEARCHCRPGWTGPACNIPTIPTTFKAQSYVKYALSFE 2653
Fly 2654 PDRFSTQV------------------------QLRFRTREEYGELFRVSDQHNREYGILEIKDGH 2694
Fly 2695 LHFRYNLNSLRTEEKDLWLNA--------------IVVNDGQWHVV---------------KVNR 2730
Fly 2731 YGSAATLELDGG----------EGRRYNETFEFVGHQWLLVDKQEGVYAGGKAEYT---GVRTFE 2782
Fly 2783 VYADYQKSCLDDIRLE----GKHLPLPPAMNGTQWGQATMARNLEKGCPSNKPCSNVICPDPFEC 2843
Fly 2844 VDLWNVYECTCGEGRIMSPDSKGCMDRNECLDMPCMNGATCINLEPRLRYRCICPDGFWGENCEL 2908
Fly 2909 VQEGQTLKLSMGALAAILVCLLIILILVLVF-VVYNRRREAHIKYPGP--------DDDVR---- 2960
Fly 2961 -------------ENIINYDDEGGGEDDMTAFDITPLQIPIGGPMPP---------ELAP----- 2998
Fly 2999 --MKMPIMYPVMTLMPGQEPNVGMFIEEHKKRADG------DPNAP-------------PFDDLR 3042
Fly 3043 NYAYEGGGST----------------------------AGSLSSLASGTDDEQQEY--DYLGAWG 3077
Fly 3078 PRFDKLANMY 3087 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
CadN | NP_001027277.1 | Cadherin_repeat | 178..301 | CDD:206637 | 37/133 (28%) |
Cadherin_repeat | 337..396 | CDD:206637 | 12/58 (21%) | ||
E_set | 449..541 | CDD:298831 | 19/107 (18%) | ||
Cadherin_repeat | 549..>625 | CDD:206637 | 23/83 (28%) | ||
Cadherin_repeat | 655..752 | CDD:206637 | 26/100 (26%) | ||
Cadherin_repeat | 765..853 | CDD:206637 | 26/98 (27%) | ||
Cadherin_repeat | 862..964 | CDD:206637 | 30/104 (29%) | ||
Cadherin_repeat | 973..1074 | CDD:206637 | 34/100 (34%) | ||
Cadherin_repeat | 1083..1166 | CDD:206637 | 26/88 (30%) | ||
Cadherin_repeat | <1219..1298 | CDD:206637 | 18/79 (23%) | ||
Cadherin_repeat | 1310..1414 | CDD:206637 | 29/106 (27%) | ||
Cadherin_repeat | 1423..1514 | CDD:206637 | 31/95 (33%) | ||
Cadherin_repeat | 1522..1630 | CDD:206637 | 31/203 (15%) | ||
Cadherin_repeat | 1638..1741 | CDD:206637 | 33/105 (31%) | ||
Cadherin_repeat | 1762..1861 | CDD:206637 | 19/106 (18%) | ||
Cadherin_repeat | 1871..1966 | CDD:206637 | 28/97 (29%) | ||
Cadherin_repeat | 1974..2083 | CDD:206637 | 32/110 (29%) | ||
EGF | 2350..2380 | CDD:278437 | 7/31 (23%) | ||
LamG | 2385..2570 | CDD:238058 | 33/223 (15%) | ||
EGF_2 | <2605..2631 | CDD:285248 | 4/25 (16%) | ||
Laminin_G_2 | 2665..2800 | CDD:280389 | 32/180 (18%) | ||
EGF_CA | 2869..2907 | CDD:238011 | 4/37 (11%) | ||
Cadherin_C | 2952..3088 | CDD:279398 | 41/226 (18%) | ||
DCHS1 | NP_003728.1 | Cadherin_repeat | 49..139 | CDD:206637 | |
Cadherin_repeat | 150..251 | CDD:206637 | 14/70 (20%) | ||
Cadherin_repeat | 260..358 | CDD:206637 | 16/97 (16%) | ||
Cadherin_repeat | 374..468 | CDD:206637 | 29/98 (30%) | ||
Cadherin_repeat | 482..574 | CDD:206637 | 23/124 (19%) | ||
Cadherin_repeat | 583..681 | CDD:206637 | 20/123 (16%) | ||
Cadherin_repeat | 689..781 | CDD:206637 | 28/103 (27%) | ||
Cadherin_repeat | 794..890 | CDD:206637 | 26/100 (26%) | ||
Cadherin_repeat | 900..991 | CDD:206637 | 24/91 (26%) | ||
Cadherin_repeat | 1004..1101 | CDD:206637 | 30/104 (29%) | ||
Cadherin_repeat | 1114..1207 | CDD:206637 | 33/95 (35%) | ||
Cadherin_repeat | 1224..1312 | CDD:206637 | 28/92 (30%) | ||
Cadherin_repeat | 1336..1432 | CDD:206637 | 26/107 (24%) | ||
Cadherin_repeat | 1445..1542 | CDD:206637 | 29/104 (28%) | ||
Cadherin_repeat | 1551..1644 | CDD:206637 | 30/93 (32%) | ||
Cadherin_repeat | 1653..1747 | CDD:206637 | 8/93 (9%) | ||
Cadherin_repeat | 1757..1851 | CDD:206637 | 22/99 (22%) | ||
Cadherin_repeat | 1860..1956 | CDD:206637 | 34/105 (32%) | ||
Cadherin_repeat | 1983..2056 | CDD:206637 | 16/92 (17%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2065..2094 | 9/28 (32%) | |||
Cadherin_repeat | 2074..2167 | CDD:206637 | 28/97 (29%) | ||
Cadherin_repeat | 2175..2273 | CDD:206637 | 32/111 (29%) | ||
Cadherin_repeat | 2282..2372 | CDD:206637 | 24/133 (18%) | ||
Cadherin_repeat | 2381..2478 | CDD:206637 | 26/169 (15%) | ||
Cadherin_repeat | 2486..2598 | CDD:206637 | 21/142 (15%) | ||
Cadherin_repeat | 2606..2702 | CDD:206637 | 23/126 (18%) | ||
Cadherin_repeat | 2712..2808 | CDD:206637 | 18/101 (18%) | ||
Cadherin_repeat | 2818..2923 | CDD:206637 | 26/146 (18%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2986..3040 | 8/64 (13%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 3062..3082 | 5/24 (21%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 3233..3298 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100175 | |
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |