DRSC/TRiP Functional Genomics Resources

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Protein Alignment CadN and vn

DIOPT Version :9

Sequence 1:NP_001027277.1 Gene:CadN / 35070 FlyBaseID:FBgn0015609 Length:3101 Species:Drosophila melanogaster
Sequence 2:NP_523942.2 Gene:vn / 38657 FlyBaseID:FBgn0003984 Length:623 Species:Drosophila melanogaster


Alignment Length:604 Identity:97/604 - (16%)
Similarity:188/604 - (31%) Gaps:221/604 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   315 AGQKSASMESNSSVTYQRFAIMGKVEATDADGDKIAYRLKSPSNV------VIIVPQTGEIMLAG 373
            :|...:|.||.||        ..:..:.:.|.:.::..|...||.      |.:.|.|  :..||
  Fly    78 SGSSESSAESGSS--------SSRSSSNNIDNNILSRLLSLNSNSLSSRSNVKLKPAT--VFDAG 132

  Fly   374 E--PTSNELLIEVIAHDLRYP------------SLVSAKPAKVLLEFLAAEPVSFIM-QHLEHDD 423
            .  |...|..:..:....:..            :|::::...:|...:.:|..|..| :|::...
  Fly   133 SSTPAQQEQHVAAVPEQQQQQQQQQQSMQKVPNTLINSQIYNLLYNGMPSEAASSKMRRHIQPSQ 197

  Fly   424 INNHSHHREKRRVTRAVRPTKRIEFTEADGDTEGKSVFQLEKETDKETFKIRDDNPWVTVETNGA 488
            :.:....|.:.....:.||..|....|:....|.    .||..:.::..:.|.|..    .|||:
  Fly   198 LPHQPESRAQLPSNYSSRPAVRSYLIESYEMPES----MLEDRSPEQAARSRRDGS----NTNGS 254

  Fly   489 VRVKKKWDYEELGPEK------------------------------------------------- 504
            .:.::....::|..:|                                                 
  Fly   255 RQQQRTGHRQQLQQDKRDHRRQRQDQQKEQRQQQQQRQHKSGNKHQQQQQQRRKHQRKHQRYNRY 319

  Fly   505 --------------TIDFWVIITNMGHNAGIKYTDNQRVIILVKDVNDEPPYFINRPLPMQAVVQ 555
                          |: |..:..:|..:..:.::...:|..:.|..:|         |.:..:|:
  Fly   320 CSARDPAQLAFAAPTV-FQGVFKSMSADRRVNFSATMKVEKVYKQQHD---------LQLPTLVR 374

  Fly   556 LNAPPNTPVFTLQARDPDTDHNIHYFIVRDRTGGRFEVDERSGVVRTRGTDLFQL-DMEYVLYVK 619
            |.       |.|.....:.|      |.|:|...|       |::|: |.||.|. |:.|:::| 
  Fly   375 LQ-------FALSNSSGECD------IYRERLMPR-------GMLRS-GNDLQQASDISYMMFV- 417

  Fly   620 AEDQNGKVDDRRFQSTPEERLSIVG-GKRAPQFYMPSYEAEIPENQKKDSDIISIKAKSFADREI 683
                         |.|.....:|:| ..|.....:.:.|..:.||..:::::..|.:|       
  Fly   418 -------------QQTNPGNFTILGQPMRVTHLVVEAVETAVSENYTQNAEVTKIFSK------- 462

  Fly   684 RYTLKAQGQGAGTFNIGPTSGIVKLAKELD---------------FED----LRQPHVYSLIVTA 729
                             |:..|:|..|:|.               |:|    .|:.::|..    
  Fly   463 -----------------PSKAIIKHGKKLRIVCEVSGQPPPKVTWFKDEKSINRKRNIYQF---- 506

  Fly   730 TEDSGGFSTSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGSNAEIEY 794
                .......:|.:|..:.:.:|.::|                   .|.|...|.:.:...|..
  Fly   507 ----KHHKRRSELIVRSFNSSSDAGRYE-------------------CRAKNKASKAIAKRRIMI 548

  Fly   795 LVSDDHFAVD--SNGIIVN 811
            ..|..||..|  ::||..|
  Fly   549 KASPVHFPTDRSASGIPCN 567

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CadNNP_001027277.1 Cadherin_repeat 178..301 CDD:206637
Cadherin_repeat 337..396 CDD:206637 12/78 (15%)
E_set 449..541 CDD:298831 17/154 (11%)
Cadherin_repeat 549..>625 CDD:206637 18/76 (24%)
Cadherin_repeat 655..752 CDD:206637 16/115 (14%)
Cadherin_repeat 765..853 CDD:206637 11/49 (22%)
Cadherin_repeat 862..964 CDD:206637
Cadherin_repeat 973..1074 CDD:206637
Cadherin_repeat 1083..1166 CDD:206637
Cadherin_repeat <1219..1298 CDD:206637
Cadherin_repeat 1310..1414 CDD:206637
Cadherin_repeat 1423..1514 CDD:206637
Cadherin_repeat 1522..1630 CDD:206637
Cadherin_repeat 1638..1741 CDD:206637
Cadherin_repeat 1762..1861 CDD:206637
Cadherin_repeat 1871..1966 CDD:206637
Cadherin_repeat 1974..2083 CDD:206637
EGF 2350..2380 CDD:278437
LamG 2385..2570 CDD:238058
EGF_2 <2605..2631 CDD:285248
Laminin_G_2 2665..2800 CDD:280389
EGF_CA 2869..2907 CDD:238011
Cadherin_C 2952..3088 CDD:279398
vnNP_523942.2 IGc2 471..538 CDD:197706 12/93 (13%)
EGF 566..598 CDD:278437 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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