Protein Alignment CadN and Cdh19

DIOPT Version :10

• Sequence 1: NP_001027277.1
• Gene: CadN / 35070
• FlyBaseID: FBgn0015609
• Length: 3101
• Species: Drosophila melanogaster
• Sequence 2: NP_001009448.1
• Gene: Cdh19 / 360835
• RGDID: 1307169
• Length: 770
• Species: Rattus norvegicus
• Alignment Length: 592
• Identity: 163/592 - (27%)
• Similarity: 282/592 - (47%)
• Gaps: 65/592 - (10%)

  Fly  1527 ITEEDDRNLPKRVLQVTATDGDKDRPQN-IVYFLTGQGIDPDNPANSKFDINRTTGEIFVLKPLD 1590
            :.||.|     .:..|.....|.|...| ..|.|.|.|       :..|.|:..||:||.::.||
  Rat    52 VPEEMD-----TIQHVGRLRSDLDNGNNSFQYKLLGTG-------DGSFSIDEKTGDIFAMQKLD 104

  Fly  1591 RDQPNGRPQWRFTVFAQ---DEGGEGLVGYADVQVNLKDINDNAPIFPQGVYFGNVTENGTAGMV 1652
            |::     |..:.:.||   ...|:.:...::..:.:.|:|||.|.|....|...|.|....|..
  Rat   105 REK-----QSLYILRAQVIDTTIGKAVEPESEFVIRVSDVNDNEPRFLDEPYEAIVPEMSPEGTF 164

  Fly  1653 VMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSPIFEIEPDTGVIKTAVCCLDRERTPDYSIQ 1717
            |:.:||.|.|||..|.:||::|::|:       |.|.|.:||.||||:.: ..:|||....|.:.
  Rat   165 VIKVTANDADDPTSGYHARILYNLEQ-------GQPYFSVEPTTGVIRIS-SKMDRELQDTYCVI 221

  Fly  1718 VVAMD----GGGLKGTGTASIRVKDINDMPPQFTKDEWFTEVDET--DGTALPEMPILTVTVHDE 1776
            :.|.|    .|.|.||.|.||::.||||..|.|.:..:...:.|:  .||.:.:     :..:|:
  Rat   222 IQAKDMLGQPGALSGTTTISIKLSDINDNKPIFKESFYRFTISESAPSGTTIGK-----IMAYDD 281

  Fly  1777 D--ETNKFQYKVIDNSGYGADKFTMVRNNDGTGSLKIVQPLDYEDQLQSNGFRFRIQVNDKGEDN 1839
            |  |..:..|.:.|:.....|  .::.|....|.:.:.:.:|:|.|   |.:..|::|.:...|.
  Rat   282 DIGENAEMDYSIEDDESQIFD--IVIDNETQEGIVILKKKVDFEHQ---NHYGIRVKVKNCHVDE 341

  Fly  1840 DNDKYHVAYSWVVVKLR-DINDNKPHFERANVEVSVFEDTKVGTELEKFKATDPDQGGKSKVSYS 1903
            :....||..|...:|:: :..|..|.|........:.|....||.:....|.|||: .:|.:.||
  Rat   342 ELAPAHVNASTTYIKVQVEDEDEPPTFLLPYYIFEIPEGKPYGTMVGTVSAVDPDR-RQSPMRYS 405

  Fly  1904 IDRSSDRQRQFAINQNGSVTIQRSLDREVVPRHQVKILAIDDGSPPKTATATLTVIVQDINDNAP 1968
            :..|    :.|.||.||::.....|||||...:.:.:.|.:..:..:.::|.:.|.|.:|||:||
  Rat   406 LIGS----KMFDINGNGTIVTTNLLDREVSAWYNLSVTATETYNVQQISSAHVYVQVLNINDHAP 466

  Fly  1969 KFLKDYRPVLPEHVPPRKVVEILATDDDDRSKSNGPPFQFRLDPSADDIIRASFKVEQDQKGANG 2033
            :|.:.|...:.|:....::::.::..|.|.|..:   ..|..:.|.:|...:||.:..:|
  Rat   467 EFSQLYETYVCENAESGEIIQTISAIDRDESIED---HHFYFNHSVEDTNNSSFILTDNQ----- 523

  Fly  2034 DGMAVISSLRS-FDREQQKEYMIPIVIKDHGSPAMTGTSTLTVIIGDVNDNKMQP--GSKD-IFV 2094
            |..|||.|.|: |..:::..:.:.|:|.|:|.|.:|.|:|||:.:.|..|::...  .||: :|:
  Rat   524 DNTAVILSNRAGFSLKEETVFYMIILIADNGIPPLTSTNTLTIQVCDCGDSRSTETCTSKELLFI 588

  Fly  2095 YNYQGQS 2101
            ..::.::
  Rat   589 MGFKAEA 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CadN	NP_001027277.1	Cadherin_repeat	178..301	CDD:206637
		CA_like	449..541	CDD:481204
		Cadherin_repeat	549..>625	CDD:206637
		Cadherin_repeat	655..752	CDD:206637
		Cadherin_repeat	765..853	CDD:206637
		Cadherin_repeat	862..964	CDD:206637
		Cadherin_repeat	973..1074	CDD:206637
		Cadherin_repeat	1083..1166	CDD:206637
		Cadherin_repeat	<1219..1298	CDD:206637
		Cadherin_repeat	1310..1414	CDD:206637
		Cadherin_repeat	1423..1514	CDD:206637
		Cadherin_repeat	1522..1630	CDD:206637	26/106 (25%)
		Cadherin_repeat	1638..1741	CDD:206637	40/106 (38%)
		CA	1770..1863	CDD:214520	20/95 (21%)
		Cadherin_repeat	1871..1966	CDD:206637	27/94 (29%)
		Cadherin_repeat	1974..2083	CDD:206637	29/109 (27%)
		EGF	2350..2380	CDD:394967
		LamG	2385..2570	CDD:238058
		EGF_2	2605..2631	CDD:400365
		LamG	2637..2797	CDD:238058
		EGF_CA	2869..2907	CDD:238011
		CADH_Y-type_LIR	3029..3088	CDD:460041
Cdh19	NP_001009448.1	Cadherin_repeat	49..142	CDD:206637	26/106 (25%)
		Cadherin_repeat	150..250	CDD:206637	41/107 (38%)
		Cadherin_repeat	259..364	CDD:206637	22/114 (19%)
		Cadherin_repeat	373..464	CDD:206637	27/95 (28%)
		Cadherin_repeat	472..570	CDD:206637	28/105 (27%)
		CADH_Y-type_LIR	704..763	CDD:460041