Protein Alignment CadN and Cdh18

DIOPT Version :10

• Sequence 1: NP_001027277.1
• Gene: CadN / 35070
• FlyBaseID: FBgn0015609
• Length: 3101
• Species: Drosophila melanogaster
• Sequence 2: NP_001101126.2
• Gene: Cdh18 / 310174
• RGDID: 1305430
• Length: 790
• Species: Rattus norvegicus
• Alignment Length: 590
• Identity: 179/590 - (30%)
• Similarity: 283/590 - (47%)
• Gaps: 109/590 - (18%)

  Fly  1521 PTYRTQITEEDDRNLPKRVLQVTATDGDKDRPQNIVYFLTGQGIDPDNPANSKFDINRTTGEIFV 1585
            |.|..::....|:.           ||      ::.|.|||:|      |.:.|.|:.|||:|..
  Rat    71 PQYVGKLHSNSDKG-----------DG------SVKYILTGEG------AGTIFIIDDTTGDIHS 112

  Fly  1586 LKPLDRDQPNGRPQWRFTVFAQ---DEGGEGLVGYADVQVNLKDINDNAPIFPQGVYFGNVTENG 1647
            .|.|||:|     :..:.:.||   ....:.|...::..:.::|||||||.|..|.|...|.|..
  Rat   113 TKSLDREQ-----KTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMS 172

  Fly  1648 TAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSPIFEIEPDTGVIKTAVCCLDRERTP 1712
            ..|..|:.:||.|.|||..|::||:||||.:       |.|.|.::|.||||:||:..:|||...
  Rat   173 DMGTSVLQVTATDADDPTYGNSARVVYSILQ-------GQPYFSVDPKTGVIRTALHNMDREARE 230

  Fly  1713 DYSIQVVAMD----GGGLKGTGTASIRVKDINDMPPQFTKDEWFTEVDETD--GTALPEMPILTV 1771
            .||:.:.|.|    .|||.|:.|.:|.:.|:||.||:|.:..:...|.|:.  |:|:.:     :
  Rat   231 HYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGK-----I 290

  Fly  1772 TVHDEDETNKFQYKVIDNSGYGADKFTMVRNNDG-------------TGSLKIVQPLDYEDQ--- 1820
            ..:|.|            :|..||....:.|.||             .|.|.:.:||:||.:
  Rat   291 KANDAD------------TGSNADMTYSITNGDGIGVFSISTDKDTREGILSLKKPLNYEKKKSY 343

  Fly  1821 -LQSNG------FRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPHFERANVEVSVFEDT 1878
             |...|      |||    :..|...|       .:.:.:.:.|: |..|.|...:..:.|:|:.
  Rat   344 TLNIEGANTHLDFRF----SHLGPFKD-------ATMLKIIVGDV-DEPPLFSMPSYVMEVYENA 396

  Fly  1879 KVGTELEKFKATDPDQGGKSKVSYSIDRSSDRQRQFAINQN-GSVTIQRSLDREVVPRHQVKILA 1942
            |:||.:....|.||| ...|.|.|.|:.|::.:|.|.|:.| |::...:.||||..|.:.:.:.|
  Rat   397 KIGTIVGTVLAQDPD-SANSLVRYFINHSTEEERFFNIDANTGTIKTSKVLDREETPWYNITVTA 460

  Fly  1943 IDDGSPPKTATATLTVIVQDINDNAPKFLKDYRPVLPEHVPPRKVVE-ILATDDDDRSKSNGPPF 2006
            .::.:|...:..::.:.|.|:|||.|:..::|..|:.|:..|.:|:. |.|||.||  .:|||.|
  Rat   461 SENDNPDLLSHVSVGIRVLDVNDNPPELAREYDIVVCENSKPGQVIHTITATDKDD--FANGPRF 523

  Fly  2007 QFRLDPSADDIIRASFKVEQDQKGANGDGMA-VISSLRSFDREQQKEYMIPIVIKDHGSPAMTGT 2070
            .|.||....  :..:|.::.     |.|..| :::..|.|.|..|..|.:||:|.|.|.|:::.:
  Rat   524 NFFLDERLP--MNPNFTLKD-----NEDNTASILTRRRRFSRTMQDVYYLPIMISDGGIPSLSSS 581

  Fly  2071 STLTV 2075
            ||||:
  Rat   582 STLTI 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CadN	NP_001027277.1	Cadherin_repeat	178..301	CDD:206637
		CA_like	449..541	CDD:481204
		Cadherin_repeat	549..>625	CDD:206637
		Cadherin_repeat	655..752	CDD:206637
		Cadherin_repeat	765..853	CDD:206637
		Cadherin_repeat	862..964	CDD:206637
		Cadherin_repeat	973..1074	CDD:206637
		Cadherin_repeat	1083..1166	CDD:206637
		Cadherin_repeat	<1219..1298	CDD:206637
		Cadherin_repeat	1310..1414	CDD:206637
		Cadherin_repeat	1423..1514	CDD:206637
		Cadherin_repeat	1522..1630	CDD:206637	27/110 (25%)
		Cadherin_repeat	1638..1741	CDD:206637	42/106 (40%)
		CA	1770..1863	CDD:214520	23/115 (20%)
		Cadherin_repeat	1871..1966	CDD:206637	29/95 (31%)
		Cadherin_repeat	1974..2083	CDD:206637	37/104 (36%)
		EGF	2350..2380	CDD:394967
		LamG	2385..2570	CDD:238058
		EGF_2	2605..2631	CDD:400365
		LamG	2637..2797	CDD:238058
		EGF_CA	2869..2907	CDD:238011
		CADH_Y-type_LIR	3029..3088	CDD:460041
Cdh18	NP_001101126.2	CA	79..157	CDD:214520	28/105 (27%)
		Cadherin_repeat	163..264	CDD:206637	43/107 (40%)
		Cadherin_repeat	272..379	CDD:206637	26/135 (19%)
		Cadherin_repeat	387..484	CDD:206637	29/97 (30%)
		Cadherin_repeat	491..589	CDD:206637	37/105 (35%)
		CADH_Y-type_LIR	723..782	CDD:460041