| Sequence 1: | NP_001027277.1 | Gene: | CadN / 35070 | FlyBaseID: | FBgn0015609 | Length: | 3101 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004924.1 | Gene: | CDH15 / 1013 | HGNCID: | 1754 | Length: | 814 | Species: | Homo sapiens |
| Alignment Length: | 1631 | Identity: | 283/1631 - (17%) |
|---|---|---|---|
| Similarity: | 417/1631 - (25%) | Gaps: | 956/1631 - (58%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1515 PPVFERPTYRTQITEEDDRNLPKRVLQVTATDGDKDRPQNIVYFLTGQGIDPDNPANSKFDINRT 1579
Fly 1580 TGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDINDNAPIFPQGVYFGNVT 1644
Fly 1645 ENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSP-IFEIEPDTGVIKTAVCCLDR 1708
Fly 1709 ERTPDY--SIQVVAMDGGGLKGTGTASIRVKDINDMPPQFTKDEWFTE-------VD----ETDG 1760
Fly 1761 TALPEMP--ILTVTVHDEDETNKFQYKVIDNSGYGADKFTMVRNNDGTGSLKIVQPLDYEDQLQS 1823
Fly 1824 NGFRFRIQVN------------DKGEDNDNDKYHVAYSWVVVKLRDINDNKPHFERANVEVSVFE 1876
Fly 1877 DTKVGTELEKFKATDPDQGGKSKVSYS----------IDRSSDRQRQFAINQNGSVTIQRSLDRE 1931
Fly 1932 VVPRHQVKILAIDDGSPPKTATATLTVIVQDINDNAPKFLKDYRPVLPEHVPPRKVVEILATDDD 1996
Fly 1997 DRSKSNGPPFQFRLDPSADDIIRASFKVEQDQKGANGDGMAVISSLRSFDREQQKEYMIPIVIKD 2061
Fly 2062 HGSPAMTGTSTLTVIIGDVNDNKMQPGSKDIFVYNYQGQSPDTPIGRVYVYDLDDWDLPDKKFYW 2126
Fly 2127 EAMEHPRFKLDEDSGMVTMRAGTREGRYHLRFKVYDRKHTQTDIPANVTVTVREIPHEAVVNSGS 2191
Fly 2192 VRLSGISDEDFIRVWNYRTQSMSRSKMDRFRDKLADLLNTERENVDIFSVQLKRKHPPLTDVRFS 2256
Fly 2257 AHGSPYYKPVRLNGIVLMHREEIEKDVGINITMVGIDECLYENQMCEGSCTNSLEISP-LPYMVN 2320
Fly 2321 ANKTALVGVRVDTIADCTCGARNFTKPESCRTTPCHNGGRCVDTRFGPHCSCPVGYTGPRCQQTT 2385
Fly 2386 RSFRGNGWAWYPPLEMCDESHLSLEFITRKPDGLIIYNGPIVPPERDETLISDFIALELERGYPR 2450
Fly 2451 LLIDFGSGTLELRVKTKKTLDDGEWHRIDLFWDTESIRMVVDFCKSAEIAEMEDGTPPEFDDMSC 2515
Fly 2516 QARGQIPPFNEYLNVNAPLQVGGLYREQFDQSLYFWHYMPTAKGFDGCIRNLVHNSKLYDLAHPG 2580
Fly 2581 LSRNSVAGCPQTEEVCAQTETTARCWEHGNCVGSLSEARCHCRPGWTGPACNIPTIPTTFKAQSY 2645
Fly 2646 VKYALSFEPDRFSTQVQLRFRTREEYGELFRVSDQHNREYGILEIKDGHLHFRYNLNSLRTEEKD 2710
Fly 2711 LWLNAIVVNDGQWHVVKVNRYGSAATLELDGGEGRRYNETFEFVGHQWLLVDKQEGVYAGGKAEY 2775
Fly 2776 TGVRTFEVYADYQKSCLDDIRLEGKHLPLPPAMNGTQWGQATMARNLEKGCPSNKPCSNVICPDP 2840
Fly 2841 FECVDLWNVYECTCGEGRIMSPDSKGCMDRNECLDMPCMNGATCINLEPRLRYRCICPDGFWGEN 2905
Fly 2906 CELVQEGQTLKLSMGALAAILVCLLIILILVLVFVV----YNRRREAHIKYPGPDDDVRENIINY 2966
Fly 2967 DDEGGGEDDMTAFDI------TPLQIPIGGPMPPEL---APM-----KMPIMYPVMTLMPGQEPN 3017
Fly 3018 VGMFIEEHKKRADGDPNAPPFDDLRNYAYEGGGSTAGSLSSLASGTDDEQQEYDYLGAWGPRFDK 3082
Fly 3083 LANMYG 3088 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CadN | NP_001027277.1 | Cadherin_repeat | 178..301 | CDD:206637 | |
| Cadherin_repeat | 337..396 | CDD:206637 | |||
| E_set | 449..541 | CDD:298831 | |||
| Cadherin_repeat | 549..>625 | CDD:206637 | |||
| Cadherin_repeat | 655..752 | CDD:206637 | |||
| Cadherin_repeat | 765..853 | CDD:206637 | |||
| Cadherin_repeat | 862..964 | CDD:206637 | |||
| Cadherin_repeat | 973..1074 | CDD:206637 | |||
| Cadherin_repeat | 1083..1166 | CDD:206637 | |||
| Cadherin_repeat | <1219..1298 | CDD:206637 | |||
| Cadherin_repeat | 1310..1414 | CDD:206637 | |||
| Cadherin_repeat | 1423..1514 | CDD:206637 | |||
| Cadherin_repeat | 1522..1630 | CDD:206637 | 28/107 (26%) | ||
| Cadherin_repeat | 1638..1741 | CDD:206637 | 41/105 (39%) | ||
| Cadherin_repeat | 1762..1861 | CDD:206637 | 22/112 (20%) | ||
| Cadherin_repeat | 1871..1966 | CDD:206637 | 29/104 (28%) | ||
| Cadherin_repeat | 1974..2083 | CDD:206637 | 4/108 (4%) | ||
| EGF | 2350..2380 | CDD:278437 | 0/29 (0%) | ||
| LamG | 2385..2570 | CDD:238058 | 22/184 (12%) | ||
| EGF_2 | <2605..2631 | CDD:285248 | 5/25 (20%) | ||
| Laminin_G_2 | 2665..2800 | CDD:280389 | 7/134 (5%) | ||
| EGF_CA | 2869..2907 | CDD:238011 | 0/37 (0%) | ||
| Cadherin_C | 2952..3088 | CDD:279398 | 65/149 (44%) | ||
| CDH15 | NP_004924.1 | Cadherin_repeat | 52..148 | CDD:206637 | 28/112 (25%) |
| Cadherin_repeat | 157..256 | CDD:206637 | 42/105 (40%) | ||
| Cadherin_repeat | 271..371 | CDD:206637 | 24/127 (19%) | ||
| Cadherin_repeat | 379..479 | CDD:206637 | 29/106 (27%) | ||
| E_set | 487..580 | CDD:298831 | 43/517 (8%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 636..663 | 13/27 (48%) | |||
| Cadherin_C | 640..781 | CDD:279398 | 65/150 (43%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 676..703 | 10/29 (34%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 130 | 1.000 | Domainoid score | I5199 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S8035 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.860 | |||||