Protein Alignment Sytalpha and SYT8

DIOPT Version :9

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_011518757.1
• Gene: SYT8 / 90019
• HGNCID: 19264
• Length: 539
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 114/415 - (27%)
• Similarity: 176/415 - (42%)
• Gaps: 82/415 - (19%)

  Fly   116 PAFWVPASVTSTAAIQQQVSNTTEESAPPTSPTGSLKSNTLSYCSTTSVPIARSDKHVVLAMHPS 180
            |..| ||  |.:...||    ..:...||.||:....:      .||::|....|    |.....
Human   136 PGGW-PA--TGSGGRQQ----GRKMGHPPVSPSAPAPA------GTTAIPGLIPD----LVAGTP 183

  Fly   181 RPRVSSMNAKLDHTKIDMTLY---------RSHSQPKTINPVSLNEVRGN--------------- 221
            .||.:.:...|....:.::..         |...:|:....|.|...||.
Human   184 WPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLES 248

  Fly   222 ----------LHVSLGYDPVGGLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHK 276
                      |.:||.:|.....:.|.|.:|.:|:|   .||.||||:|.:.....:..:|::|:
Human   249 SPGDAQQWGCLQLSLEFDFGSQEIRVGLRQAADLRP---GGTVDPYARVSVSTQAGHRHETKVHR 310

  Fly   277 RTLNPVFDEQFVFEVTAGVIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLDLSEQLKLWTPLSS 341
            .||.|||||...|.:....:...|:::.|::|..:|.|..:|..:|.|..:||...|:.|..|..
Human   311 GTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGP 375

  Fly   342 ASAQDMKVDLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKR 406
            .:|...: .:|::..||.|:||:.||.||:::||.||     ...::|||||.|: ...:|.|||
Human   376 PAATQPE-QVGELCFSLRYVPSSGRLTVVVLEARGLR-----PGLAEPYVKVQLM-LNQRKWKKR 433

  Fly   407 KTGVQRGTLNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIGNSPEVRTEEKIF 471
            ||..::||..|.:|||..|.|....::|..|...|....|...:|.:|:..:|
Human   434 KTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLG------------ 486

  Fly   472 FEEVFRAKNATAQWVPLQEPANNLA 496
                     |.|...|||..|:.||
Human   487 ---------ARASGQPLQHWADMLA 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	41/147 (28%)
		C2B_Synaptotagmin	352..488	CDD:175975	43/135 (32%)
SYT8	XP_011518757.1	C2	257..370	CDD:301316	37/115 (32%)
		C2	385..514	CDD:301316	49/145 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820