Protein Alignment Sytalpha and SYT15

DIOPT Version :9

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_024303996.1
• Gene: SYT15 / 83849
• HGNCID: 17167
• Length: 474
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 113/412 - (27%)
• Similarity: 180/412 - (43%)
• Gaps: 55/412 - (13%)

  Fly   119 WVPASVTSTAAIQQQVSNTTEESAPPTSPTGS-----LKSNTLSYCSTTSVPIARSDKH------ 172
            ||||.....||.:....:......|..||.|:     .:..:.:..:.|.....|...|
Human    64 WVPAPAVHCAAPRAAAGHQQHHGPPLCSPDGAPRRFKRRPGSPAPAAQTGETSLREQPHGGPPAV 128

  Fly   173 --VV---------LAMH-------PSRPRVSSMNAKLDHTK------------IDMTLYR-SHSQ 206
              ||         :.:|       |..|..:|  ..|.||.            |:..||: ...:
Human   129 PFVVPPTLQGRDWVPLHSGEWADAPWDPCPAS--ELLPHTSSGGLGDACMVGAINPELYKFPEDK 191

  Fly   207 PKTINPVSLNEVRGNLHVSLGYDPVGGLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQ 271
            .:|..|   :...|.|..|:.|:.....|.|.|::||:||..  |.|..|..|:.||||::.|.|
Human   192 SETDFP---DGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAP--SETCSPLVKLYLLPDERRFLQ 251

  Fly   272 TRIHKRTLNPVFDEQFVFEVTAGVIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLDLSEQLK-- 334
            ::..::|.||.|||.|:|:|::..|.:|.::..:|..|...:|..:|.....|.|..|....:
Human   252 SKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRV 316

  Fly   335 LWTPLSSASAQDMKVDLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPG 399
            :|..|.:.|.:... :.||:...|:|.....||.||:::|:.||:.:| |.....:|||:|:. .
Human   317 IWRDLEAESLEPPS-EFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQED-RGIVSVFVKVSLMN-H 378

  Fly   400 GKKIKKRKTGVQRGTLNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIGNSPEV 464
            .|.:|.:||....|::||||||..:|......|....|..|||.:.....|:.|||.::|.....
Human   379 NKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYT 443

  Fly   465 RTEEKIFFEEVF-RAKNATAQW 485
            |..|...::|:. :.|....:|
Human   444 RGRELEHWDEMLSKPKELVKRW 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	41/124 (33%)
		C2B_Synaptotagmin	352..488	CDD:175975	44/135 (33%)
SYT15	XP_024303996.1	C2A_Synaptotagmin-15-17	202..322	CDD:176036	40/121 (33%)
		C2B_Synaptotagmin-15	332..469	CDD:176054	44/136 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820