Protein Alignment Sytalpha and syt11b

DIOPT Version :10

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001156003.1
• Gene: syt11b / 794707
• ZFINID: ZDB-GENE-090601-7
• Length: 456
• Species: Danio rerio
• Alignment Length: 539
• Identity: 131/539 - (24%)
• Similarity: 224/539 - (41%)
• Gaps: 164/539 - (30%)

  Fly    22 LAQIGVYASVSFLVVSAVGAA-----------LYTTCSKRYRLNWFEQNLLESANE--------- 66
            :.:||....:|.::...:||.           |:|.|.|.|....::.:.::|.:.
Zfish     4 MTEIGAAYDMSPVLAGFIGAGVLVVAVFALIYLWTCCQKHYNRTNYKLHGIQSEHSDPLTDPPYK 68

  Fly    67 -------------------------KDEDQQREALVAGAVGYNVDNVNEVPRGKYSSGNAGNLSP 106
                                     ::...|....|.|:.|..|..||     ..|:..:|.|..
Zfish    69 FIHMLKGMSIYPDALTNSKRIIRVAREARAQTSDRVQGSKGRPVVLVN-----MDSAAESGLLGE 128

  Fly   107 TSLKSEDND----------PAFWVPASVTSTAAIQQQVSNTTEESAPPTSPTGSLKSNTLSYCST 161
            ..::.|::.          |.......:.|::|...|.|:||                    .|:
Zfish   129 KQMRLEESGHEVSRLERELPVRADYCCLDSSSASSSQTSSTT--------------------VSS 173

  Fly   162 TSVPIARSDKHVVLAMHPSRPRVSSMNAKLDHTKIDMTLYRSHSQPKTINPVSLNEVRGNLHVSL 226
            |:.|...:|:       ||                                      ||:|.:::
Zfish   174 TATPFTPADE-------PS--------------------------------------RGDLSIAI 193

  Fly   227 GYDPVGGLLNVRLLEAQNLQPRQ-FSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQFVF- 289
            .|:.....|.|.:|||:.|...: .:|:||||.|:.:||:||:..:||:.::||.|.|||.|.|
Zfish   194 DYNFPKKALVVTILEARGLPAVEGQTGSADPYVKMTILPEKKHRVKTRVLRKTLEPAFDETFTFY 258

  Fly   290 EVTAGVIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLD-------LSEQLKLWTPLSSASAQDM 347
            .|....:...|:..|:..||.:||...||.:.:.||.:|       :::|:         :.::|
Zfish   259 GVPYSSLSDLTLHFLVLSFDRFSRDDVIGEAMVPLAGVDPSTGRVHITQQI---------TKRNM 314

  Fly   348 K-VDLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQ 411
            : |..|:::|||:|.|.:.||.||::||::|..:|....|::||||:.:. .|.|:|.|:||.|:
Zfish   315 QCVSHGELLVSLSYQPVSHRLSVVVLKAKHLPKLDITGLSANPYVKLNVF-YGHKRIAKKKTHVK 378

  Fly   412 RGTLNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIG-NSPEVRTEEKIFFEEV 475
            :.|||||:||:..:||..|.|.:..:||.|:.......::.|||.::| :||
Zfish   379 KCTLNPVFNESFIYDVPAELLPDISIEFLVMDFDRTTKNQALGRLVLGADSP------------- 430

  Fly   476 FRAKNATAQWVPLQEPANN 494
              ..:..|.|   ||...|
Zfish   431 --CPSGAAHW---QEVCQN 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	43/131 (33%)
		C2B_Synaptotagmin	352..488	CDD:175975	48/136 (35%)
syt11b	NP_001156003.1	C2	186..309	CDD:472691	42/122 (34%)
		C2B_Synaptotagmin-4	320..456	CDD:176049	51/144 (35%)