Protein Alignment Sytalpha and Tc2n

DIOPT Version :9

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001076445.1
• Gene: Tc2n / 74413
• MGIID: 1921663
• Length: 489
• Species: Mus musculus
• Alignment Length: 500
• Identity: 92/500 - (18%)
• Similarity: 155/500 - (31%)
• Gaps: 220/500 - (44%)

  Fly   148 TGSLKSNTLSYCSTTSVPIARSDKHVVLAMHPSRPRVSS----MNAKL--DHTKIDMTLYR---S 203
            :.|...||:.....|||.:              :|:|..    :.:||  |..::...:.|   |
Mouse    32 SASSSQNTIGIPPLTSVLV--------------KPQVGCNEDYLLSKLPCDGKEVQFVVPRFKLS 82

  Fly   204 HSQPKTIN-PVSLNEVRGNLHVSLG------------------YDPVGGLLNVRLLEAQNLQPRQ 249
            :.||:|.. |..|:|:.|:...|.|                  |:|.             ...:.
Mouse    83 YIQPRTQGIPSHLDELEGSARASFGDQKTELCSSFYHGPSYDVYNPC-------------YMYQH 134

  Fly   250 FSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQFVFEVTAGVIDKRTVEILLYDFDAYSRH 314
            ||    |....|.||          |..|.          ::...|.|.||.::
Mouse   135 FS----PDLSRRFLP----------HCETK----------QLYGSVCDLRTSKL----------- 164

  Fly   315 VCIGGSKLHLANLDLSEQLKLW---------TPLSSASAQDM---------------KVDLGDIM 355
              .|.|.|..:.|||:...:.:         .|.||:|.::.               :.|||.:.
Mouse   165 --PGSSGLSKSMLDLTTSSQRFIQRHDSFSSVPSSSSSRKNSQGSNRSLDTITLSGDERDLGRLN 227

  Fly   356 VSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVK--VTLLGP---------GGKKIKKRKTG 409
            |.|.|..|||::.:.:::.|::.......::....:|  :||..|         |...|:..:|.
Mouse   228 VKLFYNSSAEQIWITVLQCRDISWPSSYGDTPTISIKGILTLSKPVHFKSSAKEGSNAIEFMETF 292

  Fly   410 VQRGTLNPVYNEALAFDV-----AKETLKNCVL----------EFTV------------------ 441
            |....|..:....|||.:     .|:|:..|.|          |:::
Mouse   293 VFAIKLQNLQAVRLAFKIQTQTPKKKTIGECSLSLRTLSTQEMEYSLEIIAPSKISVCQAELELG 357

  Fly   442 --------------------------------VHDGLLGSSEIL-----------------GRTL 457
                                            |..|:..|.|::                 |.|:
Mouse   358 TCFQAVNSRIQLQILEAQYLPSSSTPLTLSFFVKVGMFSSGELIYKKKTRLLKASSGRVKWGETM 422

  Fly   458 IGNSPEVRTEEKIFF------EEVFRAKNATAQ-WVPLQEPANNL 495
            |  .|.::||::|.|      ....|.|:...| |:  .|.:||:
Mouse   423 I--FPLIQTEKEIVFLIKLYSRSSVRRKHFVGQLWI--SEDSNNI 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	24/149 (16%)
		C2B_Synaptotagmin	352..488	CDD:175975	41/235 (17%)
Tc2n	NP_001076445.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..214		4/24 (17%)
		C2A_Tac2-N	239..341	CDD:176066	18/101 (18%)
		C2B_Tac2-N	352..486	CDD:176074	19/115 (17%)
		Nuclear localization signal	446..448		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900