Protein Alignment Sytalpha and Syt6

DIOPT Version :10

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_038958948.1
• Gene: Syt6 / 60565
• RGDID: 62012
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 149/479 - (31%)
• Similarity: 233/479 - (48%)
• Gaps: 83/479 - (17%)

  Fly    17 EEDISLAQIGVYASVSFLVVSAVGAALYTTCSKRY-RLNWFEQNLLESANEKDEDQQREALVAGA 80
            |:..|.|..|...|:..:||...|.||.......: :|.|......|:::....:...|.|
  Rat    46 EQSPSAADSGTSVSLLAVVVIVCGVALVAVFFFLFWKLCWMPWRNKEASSPSSANPASEIL---- 106

  Fly    81 VGYNVDNVNEVPRGKYSSGNAGNLSPTSLKSEDNDPAFWVPASVTSTAAIQQQVSNTTEESAPPT 145
                           .|..:.||::.   |.:|.....::.|:|        ::|:|:.:.  |.
  Rat   107 ---------------QSPSSRGNMAD---KLKDPSALGFLEAAV--------KISHTSPDI--PA 143

  Fly   146 SPTGSLKSNTLSYCS---TTSVPIARSDKHVVLAMH-PSRPRVSSMNAKLDHTKIDMTLYRSHSQ 206
            ....|:|.:.:.:..   .|:.| |.|.:|.....| |.:..|||::            |.:...
  Rat   144 EVQMSVKEHIMRHTKLQRQTTEP-ASSTRHTSFKRHLPRQMHVSSVD------------YGNELP 195

  Fly   207 PKTI-NPVSLNEVR----------------------GNLHVSLGYDPVGGLLNVRLLEAQNLQPR 248
            |... .|.|:..::                      |.::.||.||.....|.||:|:|.:|..:
  Rat   196 PAAAEQPTSIGRIKPELYKQKSVDGDEAKSEAAKSCGKINFSLRYDYESETLIVRILKAFDLPAK 260

  Fly   249 QFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQFVFEVTAGVIDKRTVEILLYDFDAYSR 313
            .|.|::|||.|:.||||:|...|||:|::||||.|||.|.|.|....:..|.:.:.::|||.:||
  Rat   261 DFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSR 325

  Fly   314 HVCIGGSKLHLANL----DLSEQLKLWTPLSSASAQDMKVDLGDIMVSLAYLPSAERLMVVLIKA 374
            |..||  ::.|.||    |||.:..:|..:..|:::  .||||:||.||.|||:|.||.:.:||.
  Rat   326 HDMIG--EVILDNLFEASDLSRETSIWKDIQYATSE--SVDLGEIMFSLCYLPTAGRLTLTVIKC 386

  Fly   375 RNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGTLNPVYNEALAFDVAKETLKNCVLEF 439
            |||:.: |....|||||||:|| ..|:::||:||.:::.|||||||||:.||:..|.:....|..
  Rat   387 RNLKAM-DITGYSDPYVKVSLL-CDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLI 449

  Fly   440 TVVHDGLLGSSEILGRTLIGNSPE 463
            :|:....:|.:||:|...:|.|.|
  Rat   450 SVMDYDRVGHNEIIGVCRVGISAE 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	52/148 (35%)
		C2B_Synaptotagmin	352..488	CDD:175975	52/112 (46%)
Syt6	XP_038958948.1	C2A_Synaptotagmin-1-5-6-9-10	231..355	CDD:176031	52/125 (42%)
		C2B_Synaptotagmin-3-5-6-9-10	364..497	CDD:176048	52/112 (46%)