Protein Alignment Sytalpha and Doc2g

DIOPT Version :10

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_068563.2
• Gene: Doc2g / 60425
• MGIID: 1926250
• Length: 387
• Species: Mus musculus
• Alignment Length: 380
• Identity: 93/380 - (24%)
• Similarity: 163/380 - (42%)
• Gaps: 78/380 - (20%)

  Fly   121 PASVTSTAAIQQQVSNTTEESAPPTSPTGSLKSNTLSYCSTTSVPIARS-DKHVVLA-MHPSRPR 183
            |||.....::|:.::  .:.|..|..|. .|.||...:......|:.|: |:..:|| ..||.|:
Mouse     6 PASGRQRVSMQEHMA--IDVSPGPIRPI-RLISNYFPHFYPFLEPVLRAPDRQAMLAPAIPSAPQ 67

  Fly   184 VSSMNAKLDHTKIDMTLYRSHSQPKTINPVSLNEVRGNLHVSLGYDPVGGLLNVRLLEAQNLQPR 248
            :.. |.:.:....|.|                  ..|.|..:|.:|.....|:.....|:.|:|
Mouse    68 LQP-NPEPEGDSDDST------------------ALGTLEFTLLFDEDNSALHCTAHRAKGLKP- 112

  Fly   249 QFSGTADPYAKVRLLP--DKKNFWQTRIHKRTLNPVFDEQFVFE-VTAGVIDKRTVEILLYDFD- 309
            ..:|:.|.|.|..|||  .|.:..:||..:.|..||::|...:. .|.....::|:.:.:.:..
Mouse   113 PAAGSVDTYVKANLLPGASKASQLRTRTVRGTREPVWEETLTYHGFTCQDAGRKTLRLCVCEDSR 177

  Fly   310 ------------------------AYSRHVCIGGSKL--HLANLDLSEQLKLWTPLSSASAQDMK 348
                                    |.|..:|:...||  ...:||.:..:.|:      ..::|:
Mouse   178 LRRRRRGPPLGELRVPLRKLVPNRARSFDICLEKRKLTKRPKSLDTARGMSLY------EEEEME 236

  Fly   349 VDL-----GDIMVSLAYLPSAER--LMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKR 406
            .::     |.|::||.|  |:||  |:|.:::..:|..: ||...|||:|::.|....||| .|.
Mouse   237 AEVFGEERGRILLSLCY--SSERGGLLVGVLRCVHLAPM-DANGYSDPFVRLFLHPSSGKK-SKY 297

  Fly   407 KTGVQRGTLNPVYNEALAF-----DVAKETLKNCVLEFTV-VHDGLLGSSEILGR 455
            ||.|:|.||||.:||...:     ::|::.|...|.::.: ..|..:|..::.||
Mouse   298 KTSVRRKTLNPEFNEEFFYAGHREELAQKALLVSVWDYDLGTADDFIGGVQLSGR 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	32/152 (21%)
		C2B_Synaptotagmin	352..488	CDD:175975	39/112 (35%)
Doc2g	NP_068563.2	C2A_Rabphilin_Doc2	84..209	CDD:176000	26/125 (21%)
		C2	246..378	CDD:472691	38/111 (34%)