Protein Alignment Sytalpha and syt2a

DIOPT Version :10

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_696277.2
• Gene: syt2a / 567877
• ZFINID: ZDB-GENE-060503-315
• Length: 430
• Species: Danio rerio
• Alignment Length: 413
• Identity: 128/413 - (30%)
• Similarity: 212/413 - (51%)
• Gaps: 45/413 - (10%)

  Fly   122 ASVTSTAAIQQQVSNTTEESAPPTSPT--GSLKSNTLSYCSTTSVP----IARSDKHVVLAM--- 177
            :::|...|:.....|:||...|.:...  |.:|:..|:......:|    ||.:...|||.:
Zfish    22 SALTMAPAVSTPADNSTEHQGPVSKNDVFGDIKNKFLNEMDKLPLPPWAIIAIAIVAVVLILTCC 86

  Fly   178 -----------------HPSRPRVSSMNAK--------LDHTKIDMTL-YRSHSQPKTINPVSLN 216
                             ...:..:...|.|        .|...|||.: .....:||.      .
Zfish    87 FCIVKKTCLKKKKGKKGKKGKGDMGMKNMKGGEKQEEDDDEEDIDMGITEEKEEEPKE------K 145

  Fly   217 EVRGNLHVSLGYDPVGGLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNP 281
            |..|.|..||.||.....|.|.:|:|.:|......||:|||.||.:|||||..:.|::||:||||
Zfish   146 EKLGKLQFSLDYDFSASQLTVGILQAADLLSMDSGGTSDPYVKVFILPDKKKKYDTKVHKKTLNP 210

  Fly   282 VFDEQFVFEVTAGVIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLDLSEQLKLWTPLSSASAQD 346
            ||:|.|.|::....:..:|:.:.:||||.:|:|..||..|:.:..|||::.::.|..|.||..::
Zfish   211 VFNETFHFKIPFTEMGGKTLVMSVYDFDRFSKHDVIGEVKIPMNTLDLAQPIEQWRDLDSAEKEE 275

  Fly   347 MKVDLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQ 411
            .: .||||.:||.|:|:|.:|.:.:::|:||:.: |....||||||:.|| ..||::||:||.|:
Zfish   276 PE-KLGDICISLRYVPTAGKLTICILEAKNLKKM-DVGGLSDPYVKIHLL-QNGKRLKKKKTTVK 337

  Fly   412 RGTLNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIGNSPEVRTEEKIFFEEVF 476
            :.||||.|||:.:|::.::.::......||:....:|.::.:|:..:|:..: .||.:.:.:.:.
Zfish   338 KNTLNPYYNESFSFEIPQDQMQKIQAVITVLDYDKIGKNDAIGKIWVGSKAQ-GTELRHWSDMLA 401

  Fly   477 RAKNATAQWVPLQEPANNLATSA 499
            ..:...|||.||:......||.|
Zfish   402 NPRRPIAQWHPLKPEEEVDATLA 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	50/122 (41%)
		C2B_Synaptotagmin	352..488	CDD:175975	46/135 (34%)
syt2a	XP_696277.2	Syt2_N	5..>94	CDD:409249	15/71 (21%)
		C2A_Synaptotagmin-1-5-6-9-10	148..270	CDD:176031	50/121 (41%)
		C2B_Synaptotagmin-1	279..414	CDD:176047	48/137 (35%)