DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sytalpha and mctp1

DIOPT Version :10

Sequence 1:NP_001188832.1 Gene:Sytalpha / 35068 FlyBaseID:FBgn0261089 Length:504 Species:Drosophila melanogaster
Sequence 2:XP_031755510.1 Gene:mctp1 / 548485 XenbaseID:XB-GENE-5812768 Length:919 Species:Xenopus tropicalis


Alignment Length:431 Identity:101/431 - (23%)
Similarity:165/431 - (38%) Gaps:119/431 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   121 PASVTST----AAIQ-------------QQV----SNTTEESAPPTSPTGSLKSNTLSYCSTTSV 164
            |.|:|.|    :|::             |||    .:...:|....|||.. |.:.||:..::|:
 Frog   106 PGSITGTPEPGSALRRLKDHLLPQNRGSQQVRDKDGDGQHKSGLSASPTAG-KGHRLSHQKSSSL 169

  Fly   165 PIARSDKHVVLAMHPSRPRVSSMNAKLDHTKIDMTLYRSHSQPKTINPVSLNEVRGNLHVSLGYD 229
            |  .:|     .:|..:| :|:.::.|             :|.|.......|...|.......:.
 Frog   170 P--GTD-----CLHQLQP-LSTKDSDL-------------AQSKPCGHTKNNNNVGTCTTDYSFP 213

  Fly   230 PVGGL-LNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQ---FVFE 290
            .:|.. |:|.|....||..|...||:|||.|.: :..|:.|....||| .||||:||:   |:..
 Frog   214 NLGMYQLDVTLKNGSNLAARDRGGTSDPYVKFK-IGGKEVFRSKTIHK-NLNPVWDEKVCLFIDS 276

  Fly   291 VTAGVIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLDLSEQLKLWTPLSSASAQDMKVDLGDIM 355
            :      |..:.:.::|:|...:...:|.:.|.|..::|:....:...|......|.|:....:.
 Frog   277 I------KEPLYVKVFDYDFGLQDDFMGSAFLDLTTVELNSSKDVALELRDPQHSDHKLGTIHLA 335

  Fly   356 VS------------LAYLPSAER----------------------------------LMVVLIKA 374
            ||            |:.|.|.|:                                  :.:.||:.
 Frog   336 VSLSIKDNVCIDSPLSILKSTEQNTIIKKNWKRSSKFQTQSLKLSDLHRRSQVSRGIVSITLIEG 400

  Fly   375 RNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGTLNPVYNEALAFDVAKETLKNCVLEF 439
            :.|:.: ||...||||||..|   |.:|.|.:   ....||||.:.|.:...:.:|  :..|:|.
 Frog   401 QELKAM-DANGLSDPYVKFRL---GHQKYKSK---TLPKTLNPQWREQIDMHIFEE--QGGVIEI 456

  Fly   440 TV------VHDGLLGSSEILGRTLIGNSPEVRTEEKIFFEE 474
            ||      ..|..:|...:...||   |.|...:.|:..||
 Frog   457 TVWDKDAGKRDDFIGRCHVDLSTL---SKEQTHKLKLKLEE 494

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SytalphaNP_001188832.1 C2A_Synaptotagmin-8 218..341 CDD:176033 34/126 (27%)
C2B_Synaptotagmin 352..488 CDD:175975 40/175 (23%)
mctp1XP_031755510.1 C2A_MCTP_PRT 219..339 CDD:176007 36/127 (28%)
C2B_MCTP_PRT 392..507 CDD:176022 34/115 (30%)
C2C_MCTP_PRT 546..664 CDD:176023
PRT_C <807..>864 CDD:337028
Blue background indicates that the domain is not in the aligned region.

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