Protein Alignment Sytalpha and Syt7

DIOPT Version :10

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_030106854.1
• Gene: Syt7 / 54525
• MGIID: 1859545
• Length: 719
• Species: Mus musculus
• Alignment Length: 541
• Identity: 144/541 - (26%)
• Similarity: 248/541 - (45%)
• Gaps: 84/541 - (15%)

  Fly     1 MTTHSLSAGEMDIVIREEDISLAQIGVYASVSFLVVSAVGAALYTTCSKRYRLNWFEQNLLESAN 65
            |....|:||:::: ...||.:|:......|:.    |:.|.   ..| :|.|....:|:|.:..:
Mouse   210 MVQSHLAAGKLNL-SNFEDSTLSTATTLESIP----SSAGE---PKC-QRPRTLMRQQSLQQPLS 265

  Fly    66 EKDEDQ------------QREALVAGAVGYNVDNVNEVPRGKYSSG-NAGNLSPTSLKSEDNDPA 117
            :..:.:            |.:|..|.|.|   .|.....||:...| :||:....:.....::|.
Mouse   266 QNQQGRQPSQPTTSQSLGQLQAHAASAPG---SNPRAYGRGQARQGTSAGSKYRAAGGRSRSNPG 327

  Fly   118 FW----------------------VPASVTSTAAIQQQVSNTTEESAPPTS-----------PTG 149
            .|                      |..|:....:.|...:|..:...|.|.           |.|
Mouse   328 SWDHVVGQIRNRGLDMKSFLEGRMVVLSLVLGLSEQDDFANIPDLQNPGTQQNQNAQGDKRLPAG 392

  Fly   150 SLKSNTLSYCSTTSVPIARSDKHVVLAMHPSRPRVSSMNAKLDHTKIDMTLYRSHSQPKTINPVS 214
            ....||......|  |...||:..     .:|..||.:   ::....:|.:....|:....:...
Mouse   393 GKAVNTAPVPGQT--PHDESDRRT-----ETRSSVSDL---VNSLTSEMLMLSPGSEEDEAHEGC 447

  Fly   215 LNEVRGNLHVSLGYDPVGGLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTL 279
            ..|..|.:..|:||:.....|.|::::||.|..:.||||:||:.|:.||||||:..:|::.::.|
Mouse   448 SRENLGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNL 512

  Fly   280 NPVFDEQFVFEVTAGVIDKRTVEILLY----DFDAYSRHVCIGGSKLHLANLDLSEQLKLWTPLS 340
            ||.::|.|:||   |...::.|:.:||    |:|.:||:..||...:.|..:||::....|..|.
Mouse   513 NPHWNETFLFE---GFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLK 574

  Fly   341 SASAQDMKVDLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKK 405
            ..|  |.....|::::||.|.|||..::|.:||||||:.: |...:|||||||.|:.. .|:::|
Mouse   575 PCS--DGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAM-DIGGTSDPYVKVWLMYK-DKRVEK 635

  Fly   406 RKTGVQRGTLNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIG--NSPEVRTEE 468
            :||..::..|||::||:.|||:..|.|:...:..||:....|..::::|:..:.  :.|   .|.
Mouse   636 KKTVTKKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGP---GEV 697

  Fly   469 KIFFEEVFRAKNATAQWVPLQ 489
            |.:.:.:.|.:...|||..|:
Mouse   698 KHWKDMIARPRQPVAQWHQLK 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	45/126 (36%)
		C2B_Synaptotagmin	352..488	CDD:175975	48/137 (35%)
Syt7	XP_030106854.1	C2A_Synaptotagmin-7	451..575	CDD:176032	45/126 (36%)
		C2B_Synaptotagmin-7	583..718	CDD:176050	48/139 (35%)