Protein Alignment Sytalpha and Syt7

DIOPT Version :10

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_726557.3
• Gene: Syt7 / 43783
• FlyBaseID: FBgn0039900
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 477
• Identity: 138/477 - (28%)
• Similarity: 218/477 - (45%)
• Gaps: 89/477 - (18%)

  Fly    22 LAQIGVYASVSFLVVSAVGAALYTTCSKRYRLNWFEQNLLESANEKDEDQQREALVAGAVGYNVD 86
            ||.:|:..:::..:   .|..|:.. .||.:|.:.|.|         ||::..:....|....||
  Fly    10 LAILGLIITIALFL---AGGYLWWR-HKRSQLQFIEPN---------EDEESSSYSLRAAQDIVD 61

  Fly    87 NVNEVPRGKYSSGNAGNLSPTSLKSEDNDPAFWVPASVTSTAAIQQQVSNTTEESAPPTSPT--G 149
                       |||    .||..:         ||.:...|..:|..::..........:|.  |
  Fly    62 -----------SGN----PPTKPQ---------VPVAHAITTPLQNNINRKLNGFLSLRTPLIGG 102

  Fly   150 SLKSNTLSYCSTTSVPIARSDKHVVLAMHPSRPR-VSSMNAKLDHT-------KIDMT-LYRSHS 205
            |..|.|                         :|: :||:....|.|       .|.|| :|...:
  Fly   103 SGASQT-------------------------KPQIISSVGNPGDGTTKDSANKSISMTDMYLDST 142

  Fly   206 QPKTINPVSLNEVRGNLHVSLGYDPVGGLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFW 270
            .|        :|..|.:|.||.||.....|.:::|:.:.|..:..|||:|||.:|.||||||:..
  Fly   143 DP--------SENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHRL 199

  Fly   271 QTRIHKRTLNPVFDEQFVFE-VTAGVIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLDLSEQLK 334
            :|:|.:|||||.::|.|.|| .....:..|.:.:.::|:|.:||...||...|.|..:|.:.:..
  Fly   200 ETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVDFAGKQS 264

  Fly   335 LWTPLSSASAQDMKVDLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPG 399
            .|..|...:    |...|:::.||.|.||...|.:.|||||||: ..|....|||||||.|.. |
  Fly   265 FWKALKPPA----KDKCGELLSSLCYHPSNSILTLTLIKARNLK-AKDINGKSDPYVKVWLQF-G 323

  Fly   400 GKKIKKRKTGVQRGTLNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLI-GNSPE 463
            .|:::||||.:...|||||:||:.:|:|..|.::.|.|:..|:....:|.:|::||.|: |.:..
  Fly   324 DKRVEKRKTPIFTCTLNPVFNESFSFNVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGS 388

  Fly   464 VRTEEKIFFEEVFRAKNATAQW 485
            ..:|.|.:.:.:.:.:....||
  Fly   389 GASETKHWQDMISKPRQTVVQW 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	45/123 (37%)
		C2B_Synaptotagmin	352..488	CDD:175975	52/135 (39%)
Syt7	NP_726557.3	C2A_Synaptotagmin-7	147..271	CDD:176032	45/123 (37%)
		C2B_Synaptotagmin-7	277..414	CDD:176050	52/136 (38%)