Protein Alignment Sytalpha and Mctp

DIOPT Version :10

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001261078.1
• Gene: Mctp / 37165
• FlyBaseID: FBgn0034389
• Length: 982
• Species: Drosophila melanogaster
• Alignment Length: 523
• Identity: 109/523 - (20%)
• Similarity: 189/523 - (36%)
• Gaps: 129/523 - (24%)

  Fly    24 QIGVYASVSFLVVSAVGAALYTTCSKRYRLNWFEQNLLESAN------EKDEDQQREALVAGAVG 82
            ||..:.|.|......:|..|..:.|:   ||..:.:|.||.:      :....||...:.:|.|.
  Fly    35 QISPHGSPSLQQSQRLGKHLSKSASE---LNGHDCHLSESPHISPKRAKSAVAQQLAGVSSGGVA 96

  Fly    83 YNVDNVNEV-----------PRGKYSSGNAGNLSPTSLKSEDNDPAFWVPASVTSTAAIQQQVSN 136
            ..|..:.:.           .|.| |....|..||:....|..|
  Fly    97 SGVGVLQKTHGFFNNLRHRWSRAK-SKDRLGRKSPSDFLEESTD--------------------- 139

  Fly   137 TTEESAPPTSPTGSLKSNTLSYCSTT--SVPIARSDKHVVLAMHPSRPRVSSMNAKLDHTKIDMT 199
                .|...|..||..:::..:.|||  ..|:||..:.........:....||..::|....:.:
  Fly   140 ----YAADYSSEGSSVTHSPRHRSTTIGGSPLAREFRATAKMAQVIQRFGGSMEGRIDEHPENGS 200

  Fly   200 LYRSHSQPKT---INPVSLNEVRGNLHVSLGYDPVGGLLNVRLLEAQNLQPRQFSGTADPYAKV- 260
            ...|..:..|   :..:..||:|......| ...|...|.|.|....:|.....:|.:|||.|.
  Fly   201 AGCSPPELSTQQQLEALQANELRRKREAQL-RQFVFFQLRVHLKSGSDLVAMDKNGLSDPYVKFK 264

  Fly   261 ---RLLPDKKNFWQTRIHKRTLNPVFDEQFVFEVTAGVIDKRTVEILLYDFDAYSRHVCIGGSKL 322
               |||...:.     || |.||||:||.|:..:....   :.:.:.::|:|...:...:|.:||
  Fly   265 VGGRLLHKSRT-----IH-RDLNPVWDEVFIVPIEDPF---QPIIVKVFDYDWGLQDDFMGSAKL 320

  Fly   323 HLANLDLSEQLKLWTPLSSASAQDMKVDLGDIMVSLAYLP------------------SAERL-- 367
            .|..|:|.:...:...|..:|..... .||:|:::|...|                  |::||
  Fly   321 DLTQLELGKAEDIHLQLCDSSGNGGS-GLGEILINLTLWPRSQEDKEMHFQRNSKLAESSKRLKS 384

  Fly   368 -------MVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGTLN---PVYNEA 422
                   .::|:||::|.:.:|....:|.:.|..|   |.:|.|.:.:..:|....   .:::|.
  Fly   385 QIWSSVVTILLVKAKDLPLAEDGSKLNDTHFKFRL---GNEKYKSKSSWTERWLEQFDLHLFDED 446

  Fly   423 LAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIGNSPEVRTEEKIFFEEVFRAKNATAQWVP 487
            ...::|                 |...:.:.|:.:|..|             ||:.:|....|.|
  Fly   447 QNLEIA-----------------LWNRNTLYGKAIIDLS-------------VFQRENTHGIWKP 481

  Fly   488 LQE 490
            |::
  Fly   482 LED 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	34/126 (27%)
		C2B_Synaptotagmin	352..488	CDD:175975	29/165 (18%)
Mctp	NP_001261078.1	C2A_MCTP_PRT	237..357	CDD:176007	36/129 (28%)
		C2B_MCTP_PRT	390..497	CDD:176022	24/128 (19%)
		C2C_MCTP_PRT	537..658	CDD:176023
		PRT_C	<789..900	CDD:337028