Protein Alignment Sytalpha and Syt12

DIOPT Version :9

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001259513.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 466
• Identity: 123/466 - (26%)
• Similarity: 193/466 - (41%)
• Gaps: 85/466 - (18%)

  Fly    90 EVPRGKYS---------SGN----AGNLSPTSLKSED-NDPAFWVPASVTSTAAIQQQVS----- 135
            |.|.|..|         :||    ..:||...||..: .:|...:...|.....:|:.:|
  Fly   315 ETPNGPISTDTPSTIHHNGNPFVERESLSSRLLKIHNTTNPFTGLSQRVKGPHLLQKTISEDYLF 379

  Fly   136 -----NTTEESAPPTSP-----------TGSLKSNTLSYCSTTSVPIA---RSDKHVVLAMHP-S 180
                 |....:...|.|           |.|...:.|...||.|:.:.   |:...|.|..|. |
  Fly   380 RKLGVNCPMANGNGTGPGSGHVNGNGNGTWSFGRSLLRQDSTLSLGMGLGRRNSSQVSLDSHAGS 444

  Fly   181 RPRVSSMNA-------KLDHTKIDMTLYRSH-SQPKTINPVSLNEVRGNLHVSLGYDPV-----G 232
            .|  .||:.       ..|....|.||:... .||.|       ::.|.|.|.|.||.:     |
  Fly   445 VP--GSMDGINLERAISCDSVTSDSTLFLDQLDQPYT-------QITGYLCVGLNYDQMSISNEG 500

  Fly   233 GLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQFVFEVTAGVID 297
            ..|.|.:|||:.|.......:.|.:.::.|:||.....||::.|.||.|.::|.|.|     .:.
  Fly   501 MELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNESFDF-----WLH 560

  Fly   298 KRTVEILLYDFDAYSR---HVCIGGSKLHLANLDLSEQLKLWTPLSSASAQDMKVDLGDIMVSLA 359
            ||.....|: |..|..   |..||.:::.:.  ::...:..|.|||  .::......|::|.||:
  Fly   561 KRQARHSLW-FHLYHNGPAHTLIGEAEMEIG--EMPRPITTWIPLS--DSRKCNARWGELMFSLS 620

  Fly   360 YLPSAERLMVVLIKARNLRI------VDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGTLNPV 418
            |||:||||.:|::|||||::      .:.|......:|||.|:....|.:||| |.::|...:|:
  Fly   621 YLPTAERLTIVVVKARNLKLDGEQPAPESAETVHSVFVKVYLMDKDRKVLKKR-TSLKRKDRSPI 684

  Fly   419 YNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEI-LGRTLIGNSPEVRTEEKIFFEEVFRAKNAT 482
            :||::.|.|...:|....|..||.  |:..|... ||. ::..|..|....:.:.:.:...:...
  Fly   685 FNESMIFSVPPPSLTTTQLRVTVF--GVTTSGVTPLGH-IVAGSCAVGKGLRHWHQMLSSLRKPV 746

  Fly   483 AQWVPLQEPAN 493
            |.|..|:...|
  Fly   747 AMWHVLRRAVN 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	37/130 (28%)
		C2B_Synaptotagmin	352..488	CDD:175975	45/142 (32%)
Syt12	NP_001259513.1	C2	503..602	CDD:278593	28/106 (26%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	45/144 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468153
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10024
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850