DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sytalpha and Pla2g4e

DIOPT Version :9

Sequence 1:	NP_001188832.1	Gene:	Sytalpha / 35068	FlyBaseID:	FBgn0261089	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	XP_017447688.1	Gene:	Pla2g4e / 296091	RGDID:	1310595	Length:	900	Species:	Rattus norvegicus

Alignment Length:	177	Identity:	39/177 - (22%)
Similarity:	76/177 - (42%)	Gaps:	22/177 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   234 LLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQFVFEVTAGVIDK 298
            ||.||::..:|::........|.:..:.|....:...:||......:|.::|.|.|::...|  |
  Rat   107 LLTVRIISMKNVRQADILSQTDCFVTLWLPTASQKKLRTRTISNCPHPEWNESFTFQIQTRV--K 169

  Fly   299 RTVEILLYDFDAYSRHVCIGGSKLHLANLDLSEQLKLWTPLSSASAQDMKVD-LGDIMVSLAYLP 362
            ..:|..:.|.|..::...:......|:.|.|..:..:..||:....::::|: |.:..||
  Rat   170 NVLEFSICDEDTLTQSDHLLTVLYDLSKLCLRNKTHVKFPLNPEGMEELEVEFLLEENVS----- 229

  Fly   363 SAERLMV--VLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRK 407
            |:|.|:.  ||: :|.:..::....|..|           :|.||.|
  Rat   230 SSETLITNGVLV-SRQVSCLEVHAESRRP-----------RKRKKNK 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	23/106 (22%)
Sytalpha	NP_001188832.1	C2B_Synaptotagmin	352..488	CDD:175975	14/58 (24%)
Pla2g4e	XP_017447688.1	C2_cPLA2	107..215	CDD:176001	23/109 (21%)
		cPLA2_C2	247..354	CDD:408472	6/29 (21%)
		Patatin_and_cPLA2	353..895	CDD:416256
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900