DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sytalpha and Syt2

DIOPT Version :9

Sequence 1:	NP_001188832.1	Gene:	Sytalpha / 35068	FlyBaseID:	FBgn0261089	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	XP_038946276.1	Gene:	Syt2 / 24805	RGDID:	3804	Length:	499	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	100/270 - (37%)
Similarity:	162/270 - (60%)	Gaps:	4/270 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 GNLHVSLGYDPVGGLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFD 284
            |.|..||.||.....|.|.:|:|..|......||:|||.||.||||||..::|::|::||||.|:
  Rat   221 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFN 285

  Fly   285 EQFVFEVTAGVIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLDLSEQLKLWTPLSSASAQDMKV 349
            |.|.|:|....:..:|:.:.:||||.:|:|..||..|:.:..:||.:.::.|..|.....::.:
  Rat   286 ETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPE- 349

  Fly   350 DLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGT 414
            .||||..||.|:|:|.:|.|.:::|:||:.: |....||||||:.|: ..||::||:||.|::.|
  Rat   350 KLGDICTSLRYVPTAGKLTVCILEAKNLKKM-DVGGLSDPYVKIHLM-QNGKRLKKKKTTVKKKT 412

  Fly   415 LNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIGNSPEVRTEEKIFFEEVFRAK 479
            |||.:||:.:|::..|.::...:..||:....||.:|.:|:..:| |....||.:.:.:.:...:
  Rat   413 LNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVG-SNATGTELRHWSDMLANPR 476

  Fly   480 NATAQWVPLQ 489
            ...|||..|:
  Rat   477 RPIAQWHSLK 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	49/120 (41%)
Sytalpha	NP_001188832.1	C2B_Synaptotagmin	352..488	CDD:175975	49/135 (36%)
Syt2	XP_038946276.1	Syt2_N	81..193	CDD:409249
		C2A_Synaptotagmin-1-5-6-9-10	219..341	CDD:176031	48/119 (40%)
		C2B_Synaptotagmin-1	351..486	CDD:176047	50/137 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820