Protein Alignment Sytalpha and Syt11

DIOPT Version :9

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_061274.2
• Gene: Syt11 / 229521
• MGIID: 1859547
• Length: 430
• Species: Mus musculus
• Alignment Length: 481
• Identity: 131/481 - (27%)
• Similarity: 216/481 - (44%)
• Gaps: 72/481 - (14%)

  Fly    19 DISLAQIGVYASVSFLVVSAVGAALYTTC----SKRYRLNWFE-QNLLESANEKDEDQQREALVA 78
            |:|....|:..:...:|..:|...::|.|    .|:::...:: .::|:..:...|....:..:
Mouse    12 DVSPVAAGLIGASVLVVCVSVTVFVWTCCHQQAEKKHKTPPYKFIHMLKGISIYPETLSNKKKI- 75

  Fly    79 GAVGYNVDNVNEVPRGKYSSGNAGNLSPTSLKSEDNDPAFWVPASVTSTAAIQQQVSNTTEESAP 143
                ..|....:.||.:...||....:.:.|.|.|.||....|||......|::....  |..:|
Mouse    76 ----IKVRRDKDGPRRESGRGNLLINAESGLLSHDKDPRGPSPASCMDQLPIKRDYGE--ELRSP 134

  Fly   144 PTSPT-GSLKSNTLSYCSTTSVPIARSDKHVVLAMHPSRPRVSSMNAKLDHTKIDMTLYRSHSQP 207
            .||.| |..|                       |..||.|....|...|       |....::.|
Mouse   135 MTSLTPGESK-----------------------ATSPSSPEEDVMLGSL-------TFSVDYNFP 169

  Fly   208 KTINPVSLNEVRGNLHVSLGYDPVGGLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQT 272
            |....|::.|..|.        ||              ...|..| :|||.|:.:||||::..:|
Mouse   170 KKALVVTIQEAHGL--------PV--------------MDDQTQG-SDPYIKMTILPDKRHRVKT 211

  Fly   273 RIHKRTLNPVFDEQFVF-EVTAGVIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLDLSE-QLKL 335
            |:.::||:|||||.|.| .:....:....:..|:..||.:||...||...:.||.:|.|. :::|
Mouse   212 RVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQL 276

  Fly   336 WTPLSSASAQDMKVDLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGG 400
            ...:...:.|.. :..|::.|||:|.|.|:|:.||::|||:|..:|....|.:|||||.:. .|.
Mouse   277 TRDIIKRNIQKC-ISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVY-YGR 339

  Fly   401 KKIKKRKTGVQRGTLNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIGNSPEVR 465
            |:|.|:||.|::.|||||:||:..:|:..:.|.:..:||.|:.......:|::||.::| :..|.
Mouse   340 KRIAKKKTHVKKCTLNPVFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILG-AHSVT 403

  Fly   466 TEEKIFFEEVFRA-KNATAQWVPLQE 490
            |.....:.||..: :...|:|..|.|
Mouse   404 TSGAEHWREVCESPRKPIAKWHSLSE 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	36/124 (29%)
		C2B_Synaptotagmin	352..488	CDD:175975	50/136 (37%)
Syt11	NP_061274.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	79..120		12/40 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..152		9/42 (21%)
		C2A_Synaptotagmin-4-11	157..282	CDD:176034	42/154 (27%)
		C2B_Synaptotagmin-4	291..428	CDD:176049	50/138 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925064at2759
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820