Protein Alignment Sytalpha and Syt2

DIOPT Version :10

• Sequence 1: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_033333.2
• Gene: Syt2 / 20980
• MGIID: 99666
• Length: 422
• Species: Mus musculus
• Alignment Length: 270
• Identity: 100/270 - (37%)
• Similarity: 162/270 - (60%)
• Gaps: 4/270 - (1%)

  Fly   220 GNLHVSLGYDPVGGLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFD 284
            |.|..||.||.....|.|.:|:|..|......||:|||.||.||||||..::|::|::||||.|:
Mouse   144 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFN 208

  Fly   285 EQFVFEVTAGVIDKRTVEILLYDFDAYSRHVCIGGSKLHLANLDLSEQLKLWTPLSSASAQDMKV 349
            |.|.|:|....:..:|:.:.:||||.:|:|..||..|:.:..:||.:.::.|..|.....::.:
Mouse   209 ETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPE- 272

  Fly   350 DLGDIMVSLAYLPSAERLMVVLIKARNLRIVDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGT 414
            .||||..||.|:|:|.:|.|.:::|:||:.: |....||||||:.|: ..||::||:||.|::.|
Mouse   273 KLGDICTSLRYVPTAGKLTVCILEAKNLKKM-DVGGLSDPYVKIHLM-QNGKRLKKKKTTVKKKT 335

  Fly   415 LNPVYNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEILGRTLIGNSPEVRTEEKIFFEEVFRAK 479
            |||.:||:.:|::..|.::...:..||:....||.:|.:|:..:| |....||.:.:.:.:...:
Mouse   336 LNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVG-SNATGTELRHWSDMLANPR 399

  Fly   480 NATAQWVPLQ 489
            ...|||..|:
Mouse   400 RPIAQWHSLK 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	49/120 (41%)
		C2B_Synaptotagmin	352..488	CDD:175975	49/135 (36%)
Syt2	NP_033333.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		Syt2_N	4..116	CDD:409249
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..141
		Phospholipid binding. /evidence=ECO:0000305	136..382		93/241 (39%)
		C2A_Synaptotagmin-1-5-6-9-10	142..264	CDD:176031	48/119 (40%)
		C2B_Synaptotagmin-1	274..409	CDD:176047	50/137 (36%)